(a.) Restraining within due limits of propriety; not forward, bold, boastful, or presumptious; rather retiring than pushing one's self forward; not obstructive; as, a modest youth; a modest man.
(a.) Observing the proprieties of the sex; not unwomanly in act or bearing; free from undue familiarity, indecency, or lewdness; decent in speech and demeanor; -- said of a woman.
(a.) Evincing modestly in the actor, author, or speaker; not showing presumption; not excessive or extreme; moderate; as, a modest request; modest joy.
Example Sentences:
(1) Incubation with IFN alpha or IFN gamma for 24 h resulted in only modest cytokinetic alterations, and they did not modify the effects of FUra.
(2) The active agents modestly improved treadmill exercise duration time until 1 mm ST segment depression (3%), and only propranolol and diltiazem had significant effects.
(3) Brown's model, which goes far further than those from any other senior Labour figure, and the modest new income tax powers for Holyrood devised when he was prime minister, edge the party much closer to the quasi-federal plans championed by the Liberal Democrats.
(4) The standard varies from modest to lavish – choose carefully and you could be staying in an antique-filled room with your host's paintings on the walls, and breakfasting on the veranda of a tropical garden.
(5) Bupropion, in contrast, had a modest effect only in CD-1 mice.
(6) These data support a modest role for alpha 1-adrenergic coronary vasoconstriction during exercise but fail to document an additional role for postsynaptic alpha 2-adrenergic coronary vasoconstriction during exercise.
(7) Alterations in mean systolic blood pressure appeared to be modest, consisting of a 10 percent decrease from the control level, related to sedation, and a 10 percent rise from baseline during the procedure, associated with a concomitant mild tachycardia.
(8) The patient made modest improvement with high-dose intravenous steroids.
(9) Modest reductions in renal function as measured by clearances of inulin and p-aminohippurate occurred acutely only in the patients with renal impairment.
(10) Although the debate in the US has led to some piecemeal reforms – including the USA Freedom Act and modest policy changes – many of the most intrusive government surveillance programs remain largely intact.
(11) Ultimately, both Geffen and Browne turned out to be correct: establishing the pattern for Zevon's career, the albums sold modestly but the critics loved them.
(12) Simultaneous metabolic studies of human normal fibrinogen and asialofibrinogen in rabbits revealed only a modest decrease in the half-life of the asialoprotein compared to the intact protein, with no preferential uptake of the asialo-derivative by the liver.
(13) Levels of involvement in the program were modest, with only 16% of those screened having over 10 clinical contacts and 24% still involved after 3 months.
(14) Testosterone and estrogen administration at low or modest doses to individuals with the capacity to produce GH causes GH production and IGF-I levels to increase.
(15) The more modest effect of (n-3) fatty acid supplementation in decreasing LTB4 generation was not due to blockade of the cyclooxygenase pathway.
(16) The effect of volume expansion on sodium, calcium and magnesium remaining in the proximal tubule was relatively modest and not affected by furosemide.
(17) On the other side of the Atlantic, a more modest, quieter challenger plans to take on the US electric car giant.
(18) In conclusion, a zipper technique has been outlined that allows effective continuing drainage of the septic abdomen, permits early diagnosis of organ damage, is rapid and cost effective, minimizes ventilator dependency and gastrointestinal complications, is well tolerated by the patients, and has produced a modest 65 per cent survival rate in the first 34 critically ill patients in whom it was used.
(19) In order to improve the modest oral activity of PGE2 as an inhibitor of gastric acid secretion, analogs were prepared and tested orally in histamine-challenged rats.
(20) Specific binding of insulin did not differ between control and modestly insulinopenic diabetics but was increased significantly in the severely insulinopenic diabetics.
Negligible
Definition:
(a.) That may neglicted, disregarded, or left out of consideration.
Example Sentences:
(1) Since all human cadaveric tissue is fixed whilst on the skeleton, we may assume that shrinkage of the muscles in such specimens is negligible.
(2) In group C there was a negligible increase of LVSWI despite a marked rise in PCWP.
(3) From this, it was suggested that a negligible amount of oestradiol was released from these compounds and that the oestradiol moiety was useful as a carrier for the nitrogen mustard moiety.
(4) However, the phosphorylation of a 73 kDa double band, which is negligible in the absence of added NaC1, is stimulated by this salt.
(5) Although T cells exposed to antigen in B-depleted LN of mu sm and irradiated mice gave negligible T proliferative responses in vitro, low but significant levels of primed T helper function were detected in a sensitive T helper assay in vivo.
(6) Factors of negligible importance prognostically were: complete sterilization at mammary and axillary level after radiotherapy, persistence of florid cancer tissue at mammary level and histiocytosis of the axillary lymph nodes.
(7) In addition, the trends in the three sets of data for the catalytic subunit indicate that ionic bonds are involved in binding PALA to the active site, and that non-productive binding by L-Asp is negligible under these experimental conditions.
(8) We feel that the above technique is simple and definitive with negligible complications.
(9) Activity peaked during the period corresponding to evening twilight and was negligible during the morning twilight period; in contrast, death feigning peaked during the morning twilight period.
(10) The adverse effects were negligible--one patient had light urticarial rash and pruritus.
(11) In contrast, corticosterone, testosterone, progesterone and oestradiol showed negligible ability to displace [3H]1 alpha,25-(OH)2D3 from its receptor.
(12) Despite its negligible amount, the DIssE RNA in virions appears to serve as the template for the synthesis of DIssE RNA in infected cells.
(13) Facial pain is a very constant phenomenon which does not- or only to a negligible degree--change over an agelong course.
(14) An abrupt decrease of the liver glycogen was found as well as a negligible rise of the blood sugar.
(15) In conclusion, respiratory morbidity is not negligible.
(16) The influence of sample preparation for electrophoresis was found to be negligible.
(17) "This age group feeds Radio 4's core audience and it would in my judgment be negligent not to [look at this]," Liddiment added.
(18) As far as the cardiovascular systems of the fetus and neonate are concerned the effects in the dosage used are negligible.
(19) Desaturation by 4 M MgCl2 indicated that the amount of endogenously bound hormone was negligible in our membrane preparations.
(20) With monoclonal antibody AA1, immunostaining was entirely specific for mast cell granules, and there was negligible background staining in a range of tissues including lung, tonsil, colon, gastric mucosa, skin, and pituitary.