(a.) Restraining within due limits of propriety; not forward, bold, boastful, or presumptious; rather retiring than pushing one's self forward; not obstructive; as, a modest youth; a modest man.
(a.) Observing the proprieties of the sex; not unwomanly in act or bearing; free from undue familiarity, indecency, or lewdness; decent in speech and demeanor; -- said of a woman.
(a.) Evincing modestly in the actor, author, or speaker; not showing presumption; not excessive or extreme; moderate; as, a modest request; modest joy.
Example Sentences:
(1) Incubation with IFN alpha or IFN gamma for 24 h resulted in only modest cytokinetic alterations, and they did not modify the effects of FUra.
(2) The active agents modestly improved treadmill exercise duration time until 1 mm ST segment depression (3%), and only propranolol and diltiazem had significant effects.
(3) Brown's model, which goes far further than those from any other senior Labour figure, and the modest new income tax powers for Holyrood devised when he was prime minister, edge the party much closer to the quasi-federal plans championed by the Liberal Democrats.
(4) The standard varies from modest to lavish – choose carefully and you could be staying in an antique-filled room with your host's paintings on the walls, and breakfasting on the veranda of a tropical garden.
(5) Bupropion, in contrast, had a modest effect only in CD-1 mice.
(6) These data support a modest role for alpha 1-adrenergic coronary vasoconstriction during exercise but fail to document an additional role for postsynaptic alpha 2-adrenergic coronary vasoconstriction during exercise.
(7) Alterations in mean systolic blood pressure appeared to be modest, consisting of a 10 percent decrease from the control level, related to sedation, and a 10 percent rise from baseline during the procedure, associated with a concomitant mild tachycardia.
(8) The patient made modest improvement with high-dose intravenous steroids.
(9) Modest reductions in renal function as measured by clearances of inulin and p-aminohippurate occurred acutely only in the patients with renal impairment.
(10) Although the debate in the US has led to some piecemeal reforms – including the USA Freedom Act and modest policy changes – many of the most intrusive government surveillance programs remain largely intact.
(11) Ultimately, both Geffen and Browne turned out to be correct: establishing the pattern for Zevon's career, the albums sold modestly but the critics loved them.
(12) Simultaneous metabolic studies of human normal fibrinogen and asialofibrinogen in rabbits revealed only a modest decrease in the half-life of the asialoprotein compared to the intact protein, with no preferential uptake of the asialo-derivative by the liver.
(13) Levels of involvement in the program were modest, with only 16% of those screened having over 10 clinical contacts and 24% still involved after 3 months.
(14) Testosterone and estrogen administration at low or modest doses to individuals with the capacity to produce GH causes GH production and IGF-I levels to increase.
(15) The more modest effect of (n-3) fatty acid supplementation in decreasing LTB4 generation was not due to blockade of the cyclooxygenase pathway.
(16) The effect of volume expansion on sodium, calcium and magnesium remaining in the proximal tubule was relatively modest and not affected by furosemide.
(17) On the other side of the Atlantic, a more modest, quieter challenger plans to take on the US electric car giant.
(18) In conclusion, a zipper technique has been outlined that allows effective continuing drainage of the septic abdomen, permits early diagnosis of organ damage, is rapid and cost effective, minimizes ventilator dependency and gastrointestinal complications, is well tolerated by the patients, and has produced a modest 65 per cent survival rate in the first 34 critically ill patients in whom it was used.
(19) In order to improve the modest oral activity of PGE2 as an inhibitor of gastric acid secretion, analogs were prepared and tested orally in histamine-challenged rats.
(20) Specific binding of insulin did not differ between control and modestly insulinopenic diabetics but was increased significantly in the severely insulinopenic diabetics.
Optimism
Definition:
(n.) The opinion or doctrine that everything in nature, being the work of God, is ordered for the best, or that the ordering of things in the universe is such as to produce the highest good.
(n.) A disposition to take the most hopeful view; -- opposed to pessimism.
Example Sentences:
(1) The optimal size for stimulation was between 5 degrees and 12 degrees (visual angle).
(2) In addition, intravenous injection of complexes into rabbits showed optimal myocardial images with agents of intermediate lipophilicity.
(3) More research and a national policy to provide optimal nutrition for all pregnant women, including the adolescent, are needed.
(4) A beta-adrenergic receptor cDNA cloned into a eukaryotic expression vector reliably induces high levels of beta-adrenergic receptor expression in 2-12% of COS cell colonies transfected with this plasmid after experimental conditions are optimized.
(5) Enhanced sensitivity to ITDs should translate to better-defined azimuthal receptive fields, and therefore may be a step toward achieving an optimal representation of azimuth within the auditory pathway.
(6) T cell costimulation by molecules on the antigen presenting cell (APC) is required for optimal T cell proliferation.
(7) This optimization resulted in products which are now studied in-vivo.
(8) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(9) In general, optimal DAGAT activity in vitro was observed when long-chain unsaturated acyl-CoAs and diacylglycerols (DAGs) containing long acyl chains were used as substrates for in vitro TAG synthesis (although 1,2-didecanoin was also very effective).
(10) In conclusion, autoimmune thyroiditis in an animal model can be prevented by reducing thyroidal iodine or its metabolism and optimal effects require intervention at the embryonic stage.
(11) Research must continue to determine the optimal regimen that suppresses testosterone activity with the least amount of toxicity.
(12) We present the analysis both formally and in geometric terms and show how it leads to a general algorithm for the optimization of NMR excitation schemes.
(13) The effect of exclusion versus inclusion of the fiducial timing point optimizing routine in the signal averaging program was examined in 21 patients.
(14) The nurse is in an optimal position to plan and deliver a program and determine its effectiveness.
(15) elution patterns of the adducts formed by DBF metabolites with DNA and obtained in vivo at the optimal exposure time of 42-48 h were qualitatively very similar to the patterns obtained in vitro, but their amplitude was quantitatively reduced.
(16) Incubation of the blocked filters with radiolabeled DNA under optimal binding conditions and subsequent autoradiography reveals high-affinity DNA-protein interactions.
(17) A technique is therefore described using 3-D images and reconstruction of high-resolution films, which allows rapid examination of the menisci in optimal planes.
(18) The data of first 1000 first-born, non-malformed, mature (greater than or equal to 2500 g) offspring of participants in the Hungarian "Optimal" Family Planning Programme were evaluated.
(19) Molecular mass of the native enzyme is 560,000 and optimal reaction temperature is 70 degrees C. Km value for ribulose 1,5-bisphosphate is 0.27 mM.
(20) Optimal yields of 7-ketolithocholic acid and 7-ketodeoxycholic acid were obtained after 78 h of incubation.