(v. t.) To change somewhat the form or qualities of; to alter somewhat; as, to modify a contrivance adapted to some mechanical purpose; to modify the terms of a contract.
(v. t.) To limit or reduce in extent or degree; to moderate; to qualify; to lower.
Example Sentences:
(1) In addition, this pretreatment protocol did not modify the recipient immune response against B-lymphocyte alloantigens which developed in unsuccessful transplants.
(2) Experience of pain is modified by intern and extern influences, and it can appear very multiformly in the chronicity.
(3) The absorption of ingested Pb is modified by its chemical and physical form, by interaction with dietary minerals and lipids and by the nutritional status of the individual.
(4) Incubation with IFN alpha or IFN gamma for 24 h resulted in only modest cytokinetic alterations, and they did not modify the effects of FUra.
(5) These authors, therefore, conclude that this modified surgical approach is a viable alternative to the previously described procedures for resistant metatarsus adductus.
(6) In the clinical trials in which there was complete substitution of fat-modified ruminant foods for conventional ruminant products the fall in serum cholesterol was approximately 10%.
(7) Examination of the SON in such animals revealed that the oxytocinergic system is already modified by day 12 of dioestrus; during suckling-induced lactation, the anatomical changes are identical to those seen during a normal post-partum lactation.
(8) This modified endocrine activity in brook trout may reflect adjustment to adverse external ionic conditions.
(9) The secretion of GH as measured by increased plasma level, in response to oral administration of 500 mg L-dopa or 30 min-infusion of arginine, was not modified by prior intravenous administration of 200 micrograms GH-releasing hormone (GHRH).
(10) Thus, our results indicate that calbindin-D28k is a useful marker for the projection system from the matrix compartment and that its expression is modified in patients with progressive supranuclear palsy and striatal degeneration.
(11) Both systems indicated that the Kupffer cell modified endotoxin by enriching the lipid content of the molecule and shortening the length of the O-antigen.
(12) To become president of Afghanistan , Ashraf Ghani Ahmadzai changed his wardrobe and modified his name, gave up coffee, embraced a man he once denounced as a “known killer” and even toyed with anger management classes to tame a notorious temper.
(13) Pretreatment of cells with maitotoxin did not modify 125I-omega-conotoxin and [3H]PN 200-110 binding to PC12 membranes.
(14) The quantity of social ties, the quality of relationships as modified by type of intimate, and the baseline level of symptoms measured five years earlier were significant predictors of psychosomatic symptoms among this sample of women.
(15) Ultraviolet difference spectrophotometry indicates that the inactivated enzyme retains its capacity for binding the nucleotide substrates whereas the spectral perturbation characteristic of 3-phosphoglycerate binding is abolished in the modified enzyme.
(16) Lipoprotein electrophoresis on agarose gel has been modified to allow estimation of the absolute quantity of each fraction.
(17) A modified method of two-dimensional gel electrophoresis has been developed for detecting acidic eukaryotic ribosomal proteins.
(18) It is clear that before general release of a new living feline infectious enteritis vaccine, there must be satisfactory evidence that concurrent infection will not affect the safety of the modified antigen.In cats infected with feline infectious enteritis there appears to be a short period, coinciding with the onset of leucopaenia, during which they are highly infectious.
(19) The effect of modifying the periodate-susceptible methionine residues in chicken ovotransferrin was small but significant.
(20) The ability of adenosine to modify the effects of noradrenaline on action potential characteristics was also investigated.
Shuffle
Definition:
(v. t.) To shove one way and the other; to push from one to another; as, to shuffle money from hand to hand.
(v. t.) To mix by pushing or shoving; to confuse; to throw into disorder; especially, to change the relative positions of, as of the cards in a pack.
(v. t.) To remove or introduce by artificial confusion.
(v. i.) To change the relative position of cards in a pack; as, to shuffle and cut.
(v. i.) To change one's position; to shift ground; to evade questions; to resort to equivocation; to prevaricate.
(v. i.) To use arts or expedients; to make shift.
(v. i.) To move in a slovenly, dragging manner; to drag or scrape the feet in walking or dancing.
(n.) The act of shuffling; a mixing confusedly; a slovenly, dragging motion.
(n.) A trick; an artifice; an evasion.
Example Sentences:
(1) When randomly shuffled herpes virus sequences were examined each algorithm detected many such patterns but the scoring algorithm found fewer than the selection algorithm.
(2) The kinetics of appearance of the slowly-dissociating form, and its dependence upon ionic strength, are fully consistent with the shuffling model.
(3) By shuffling constant region domains between IgG3 and IgG4, we showed that sequence variation in the CH3 domain is responsible for WMac-derived RF differentiation of IgG3 and IgG4.
(4) The new channel, which has been developed under the code name Project Shuffle, will allow viewers who missed the first live broadcast of Channel 4's most popular shows the opportunity to catch up with them over the next seven nights.
(5) The data thus obtained are compatible with those produced in previous exon-shuffling experiments, but permit a much more precise definition of recognized epitope(s).
(6) The job shuffle follows a major restructure of ITN last November, as part of a move to bring the company back to profitability, which included ITN Productions bringing together the multimedia production arms of ITN On, ITN Factual and ITN Consulting.
(7) Gene segment duplication and exon shuffling may have contributed to the evolution of this cell type-specific transcriptional regulatory gene.
(8) Sometimes, it is because a senior minister will not accept the sideways shuffle that is envisaged for them, and sometimes it is simply because the prime minister loses his nerve.
(9) Thirty-six percent of the cases displayed at least 1 of the following "parkinsonian symptoms": bradykinesia, tremor, rigidity, loss of postural reflexes and a shuffling gait.
(10) That rock-star treatment then gets paid off with stale one-liners from the previous decade that sound like they were organized by shuffling notecards.
(11) By shuffling nucleotides in a given sequence or by substituting selected nucleotides to alter various positions in both periodic and aperiodic sequences, we have found that an excess or deficiency of a given nucleotide at one of the three positions in a triplet reading frame can simulate the periodic characteristic.
(12) Her stooped figure shuffles slowly in, manoeuvring a giant shopping trolley around the door.
(13) Analysis of protein sequences shows that many proteins in multicellular organisms have evolved by a process of exon shuffling, deletion and duplication.
(14) Leaders who are particularly nervy end up rearranging the Whitehall furniture to try to keep everyone happy – removing energy from trade and industry, or science from education, to create new fiefdoms; or adding such responsibilities back in to try to convince ministers disgruntled at not being shuffled up that they are instead being promoted through the expansion of their empire.
(15) These divergences involve entire peptide subsegments and are concentrated in the same domains as are encoded by alternatively spliced exons, suggesting that exon shuffling may have contributed to the evolution of troponin T.
(16) We have chosen to carry out the exon shuffling experiments between these two different types of class I genes, because they are structurally similar and did not evolve to carry out identical functions.
(17) This review also discusses site-directed mutagenesis and exon shuffling studies and the effect of these changes on the function of Ia genes.
(18) Comparison of the sequences of the 5' ends of the lck and c-src genes suggests that divergence of these two genes involved exon shuffling and that a homolog of the neuronal c-src(+) exon is not present in lck.
(19) The ball is in Cameron's court – or in someone else's court when his Conservative-led coalition shuffles off into history.
(20) Here, we report the first direct evidence for exon shuffling.