(n.) The act of modulating, or the state of being modulated; as, the modulation of the voice.
(n.) Sound modulated; melody.
(n.) A change of key, whether transient, or until the music becomes established in the new key; a shifting of the tonality of a piece, so that the harmonies all center upon a new keynote or tonic; the art of transition out of the original key into one nearly related, and so on, it may be, by successive changes, into a key quite remote. There are also sudden and unprepared modulations.
Example Sentences:
(1) The variation in thickness of the LLFL may modulate the species causing damage to the cells below it.
(2) These included bringing in the A* grade, reducing the number of modules from six to four, and a greater attempt to assess the whole course at the end.
(3) The vascular endothelium is capable of regulating tissue perfusion by the release of endothelium-derived relaxing factor to modulate vasomotor tone of the resistance vasculature.
(4) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
(5) Gel filtration of the 40,000 rpm supernatant fraction of a homogenate of rat cerebral cortex on a Sepharose 6B column yielded two fractions: fraction II with the "Ca(2+) plus Mg(2+)-dependent" phosphodiesterase activity and fraction III containing its modulator.
(6) This modulation results from repetitive, alternating bursts of excitatory and inhibitory postsynaptic potentials, which are caused at least in part by synaptic feedback to the command neurons from identified classes of neurons in the feeding network.
(7) Modulation of the voltage-gated K+ conductance in T-lymphocytes by substance P was examined.
(8) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(9) This study examines the role of sex hormones in modulating the expression of autoimmunity in NZB x NZW F1 mice.
(10) More needs to be known about the direct and indirect modulation of cytokine production by cyclosporin A in connective tissues, in order to understand its potential value in clinical disorders.
(11) We suggest that neuronal PACAP may serve to modulate motor activity and secretion in the lower esophageal sphincter region.
(12) Furthermore, modulation of the assay by prostaglandin E2 (PGE2) was used to increase its sensitivity.
(13) Masking experiments are demonstrated for electrical frequency-modulated tone bursts from 1,000 to 10,000 cps and from 10,000 to 1,000 cps with superimposed clicks.
(14) From these results, BM-Eo are naive and seem to be a good indicator for eosinophilotaxis and its modulation.
(15) Administration of modulators in combinations of threes resulted in still further reduction of tumor incidences to 22.2% (SS + MC + AA), 19.2% (SS + MC + RA), 16% (MC + AA + RA) and 23.1% (AA + RA + SS).
(16) These findings suggest that activation of protein kinase C may act as a feedback inhibitor to modulate ligand-mediated increases in [Ca2+]i.
(17) These studies demonstrate that vWF interaction with GP Ib may be modulated by botrocetin binding to a discontinuous site located within residues 539-643.
(18) This contrasts sharply with the reduction in both the frequency and surface area of sensory neuron active zones that accompanies long-term habituation, and suggests that modulation of active zone number and size may be an anatomical correlate that lies in the long-term domain.
(19) Thus, it appears that the modulation of the phosphorylation of these cytosolic proteins represents an essential step in the regulation of T lymphocyte activation.
(20) Energy conformational calculations on these compounds were also carried out using the empirical energy program called MOLMEC, in order to better understand how the 4-R substituents modulate receptor binding affinities and efficacies.
Transition
Definition:
(n.) Passage from one place or state to another; charge; as, the transition of the weather from hot to cold.
(n.) A direct or indirect passing from one key to another; a modulation.
(n.) A passing from one subject to another.
(n.) Change from one form to another.
Example Sentences:
(1) Clinical signs of disease developed as early as 15 days after transition to the experimental diets and included impaired vision, decreased response to external stimuli, and abnormal gait.
(2) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
(3) The high transition enthalpy for kerasin is ascribed to a lesser accommodation of gauche conformers in the hydrocarbon chains just below the transition temperature.
(4) Local embolism, vertebral distal-stump embolism, the dynamics of hemorrhagic infarction and embolus-in-transit are briefly described.
(5) Each profile is described by a simple sequence of band transitions (BT-sequence).
(6) These two types of transfer functions are appropriate to explain the transition to anaerobic metabolism (anaerobic threshold), with a hyperbolic transfer characteristic representing a graded transition; and a sigmoid transfer characteristic representing an abrupt transition.
(7) In addition to the phase diagrams reported here for these two binary mixtures, a brief theoretical discussion is given of other possible phase diagrams that may be appropriate to other lipid mixtures with particular consideration given to the problem of crystalline phases of different structures and the possible occurrence of second-order phase transitions in these mixtures.
(8) Biotin-avidin immunoperoxidase analysis for hCG was performed on all paraffin blocks containing carcinoma-in-situ, grade I, grade II, and grade III transitional cell carcinoma.
(9) The growth of transitional epithelial cells with different growth media and growth supports was examined.
(10) Subthreshold concentrations of the drug to induce complete blockade (5 x 10(-8)M) allowed to observe a greater depression of bioelectric cell characteristics in primary than in transitional fibres.
(11) The B cell epitopes included regions of transition between the more hydropathic (including the N-terminal end of the F1 and F2 protein) and hydrophilic sequences.
(12) There was no correlation between disturbed gastric clearance, impaired gall bladder contraction, and prolonged colonic transit time in the patients with cardiovascular autonomic neuropathy nor was there a correlation between any disturbed motor function and age or duration of diabetes.
(13) In addition, transitional macrophages with both positive granules and positive RER, nuclear envelope, negative Golgi apparatus (as in exudate- resident macrophages in vivo), and mature macrophages with peroxidatic activity only in the RER and nuclear envelope (as in resident macrophages in vivo) were found.
(14) Interphase death thus involves a discrete, abrupt transition from the normal state and is not merely the consequence of progressive and degenerative changes.
(15) Sialosyl-Tn antigen expression also was observed in intestinal metaplasia of the stomach and in transitional mucosa adjacent to the colorectal carcinoma, which are considered to be cancer-related lesions.
(16) Refolding was observed by injection of denatured protein into columns having isocratic concentrations in the transition and native base-line zones.
(17) The mutant ribosomes prepared from the transition-phase cells have much lower activity (below 60%) for poly(U)-directed polyphenylalanine synthesis than those in exponentially growing or resting stationary-phase cells.
(18) Aside from typical nuclear spheroids, irregularly shaped nuclei were frequently seen, associated with increased nuclear folds, transitional stages between nuclear folds and nuclear spheroids were also present.
(19) The surface film transition is especially noted in the pressure-area curve of the surfactant and approximates in two dimensions the broad thermotropic phase transition of the bulk phase surfactant.
(20) Stool weights, defecation frequencies, and transit times in this group are much closer to those of westernized whites than to rural blacks.