(n.) One of the very small invisible particles of which all matter is supposed to consist.
(n.) The smallest part of any substance which possesses the characteristic properties and qualities of that substance, and which can exist alone in a free state.
(n.) A group of atoms so united and combined by chemical affinity that they form a complete, integrated whole, being the smallest portion of any particular compound that can exist in a free state; as, a molecule of water consists of two atoms of hydrogen and one of oxygen. Cf. Atom.
Example Sentences:
(1) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(2) Glucocorticoids have numerous effects some of which are permissive; steroids are thus important not only for what they do, but also for what they permit or enable other hormones and signal molecules to do.
(3) The results demonstrated that K2PtCl4 was bound to a greater degree than CDDP in this system with 3-5 and 1-2 platinum atoms respectively, bound per transferrin molecule.
(4) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
(5) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(6) However, the presence of these two molecules was restored if testosterone was supplemented immediately after orchiectomy.
(7) In the second approach, attachment sites of DTPA groups were directed away from the active region of the molecule by having fragment E1,2 bound in complex, with its active sites protected during the derivatization.
(8) PMNs could be primed for PMA-triggered oxidative burst by muramyl peptide molecules (MDP) and two of its adjuvant active nonpyrogenic derivatives.
(9) These same molecules may be equally responsible for the pathologic characteristics of the immune response seen, for example, in inflammatory bowel diseases.
(10) A cDNA library prepared from human placenta has been screened for sequences coding for factor XIIIa, the enzymatically active subunit of the factor XIII complex that stabilizes blood clots through crosslinking of fibrin molecules.
(11) T cell costimulation by molecules on the antigen presenting cell (APC) is required for optimal T cell proliferation.
(12) The lipid A moiety was shown to be responsible for this novel biological activity of the LPS molecule.
(13) Both systems indicated that the Kupffer cell modified endotoxin by enriching the lipid content of the molecule and shortening the length of the O-antigen.
(14) Photoreactions induced in that proper sensitizer molecules absorb UV-light or visible light.
(15) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(16) Flow cytofluorometric analysis of the strain distribution of the molecules defined by the mAb revealed that two of the antibodies (I-22 and III-5) were directed against nonpolymorphic determinants of Thy-1, whereas V-8 mAb reacted only with Thy-1.2+ lymphocytes.
(17) At a fixed concentration of nucleotide the effectiveness of elution was proportional to the charge on the eluting molecule.
(18) The relative rates of reduction of several spin-labeled molecules that partition differently across the hy-drophobic-interface of inner membranes from rat liver mitochondria were investigated.
(19) The seve polypeptide chains investigated had generalyy similar properties; all contained two residues per molecule of tryptophan and N-acetylserine was the common N-terminal amino acid residue.
(20) Much information has accumulated on the isolation and characterization of a heterogeneous group of molecules that inhibit one or more of the bioactivities of interleukin 1.
Up
Definition:
(adv.) Aloft; on high; in a direction contrary to that of gravity; toward or in a higher place or position; above; -- the opposite of down.
(adv.) From a lower to a higher position, literally or figuratively; as, from a recumbent or sitting position; from the mouth, toward the source, of a river; from a dependent or inferior condition; from concealment; from younger age; from a quiet state, or the like; -- used with verbs of motion expressed or implied.
(adv.) In a higher place or position, literally or figuratively; in the state of having arisen; in an upright, or nearly upright, position; standing; mounted on a horse; in a condition of elevation, prominence, advance, proficiency, excitement, insurrection, or the like; -- used with verbs of rest, situation, condition, and the like; as, to be up on a hill; the lid of the box was up; prices are up.
(adv.) To or in a position of equal advance or equality; not short of, back of, less advanced than, away from, or the like; -- usually followed by to or with; as, to be up to the chin in water; to come up with one's companions; to come up with the enemy; to live up to engagements.
(adv.) To or in a state of completion; completely; wholly; quite; as, in the phrases to eat up; to drink up; to burn up; to sum up; etc.; to shut up the eyes or the mouth; to sew up a rent.
(adv.) Aside, so as not to be in use; as, to lay up riches; put up your weapons.
(prep.) From a lower to a higher place on, upon, or along; at a higher situation upon; at the top of.
(prep.) From the coast towards the interior of, as a country; from the mouth towards the source of, as a stream; as, to journey up the country; to sail up the Hudson.
(prep.) Upon.
(n.) The state of being up or above; a state of elevation, prosperity, or the like; -- rarely occurring except in the phrase ups and downs.
(a.) Inclining up; tending or going up; upward; as, an up look; an up grade; the up train.