(1) For this purpose the molecular models of Monod-Wyman-Changeux (MWC) and of Koshland-Nemethy-Filmer (KNF) are tested by showing how the different plots, direct, reciprocal, Scatchard and Hill, vary as do the parameters considered in these models.
(2) The first Jacques Monod Conference was held in Roscoff, Brittany on 1-5 June 1987 and dealt with the topic of 'Selection of Lymphocyte Repertoires' (organizers F. W. Alt, Columbia University, New York.
(3) It is shown in the present study that the discrepancy can be explained equally as well if Monod's model for the feed relation is retained and if, in addition, growth of bacteria on the chemostat walls is allowed for in the model equations.
(4) The observed distribution of the three assembly free energies among the ten species was found to be incompatible with the two-state mechanism of allosteric control (J. Monod, J. Wyman and J. P. Changeaux, J. Mol.
(5) This relation could be described by the Monod equation.
(6) Circular dichroism spectra of the complex and the kinetic data support a model for this cooperative binding that is formally equivalent to the "allosteric" one proposed for oligomeric proteins by Monod et al.
(7) The heterotropic interactions between the allosteric inhibitor and activator binding centers are consistent with the predictions of the Monod-Wyman-Changeux model which involves two conformational states of the enzyme (of which one is catalytically inactive) differing in their affinity for the ligands.
(8) The curve differs from the classic chemostat curve described with the Monod equation, thus indicating changes in metabolism at different growth rates.
(9) The dual-substrate model was used to analyze the data because the theoretical assumptions of the Monod equation were not met.
(10) The kinetic characteristics of the enzyme were consistent with the K type allosteric model of Monod et al.
(11) However, for the compounds tested, the variance left by analyses using one value for each parameter of Monod kinetics was less than double the unexplained variance left by individual analyses of the data from each treatment.
(12) Extension of the theory to provide quantitative expressions for multivalent enzymes has made possible the numerical simulation of thermodynamic non-ideality effects on systems conforming with the Monod and Koshland models of allostery.
(13) Electric and magnetic fields around air-gap, diplode, monode and circuplode applicators were mapped by the author.
(14) The rate of substrate uptake is modeled with a Monod-type relationship.
(15) The exchange of hypothesis II for hypothesis I more strongly favors views of cooperative oxygen binding involving both types of subunits, as required if the allosteric model of Monod, Wyman, and Changeux [(1965) J. Mol.
(16) The salt bridges are found to be partially coupled to the ligation state in the deoxy quaternary structure; it is shown that a Monod-Wyman-Changeux-type model, in which the salt bridges are coupled only to quaternary structural change, is inconsistent with the data for delta H1.
(17) The concerted model of Monod, Wyman and Changeux and the sequential model of Koshland, Némethy and Filmer were formulated to account for positively cooperative binding.
(18) The cooperativity of enzyme-substrate interactions is investigated in the concerted allosteric model of Monod, Wyman and Changeux.
(19) Rhodotorula mucilaginosa was grown in p-hydroxybenzoate-limited chemostats over the dilution rate (D) range 0.01 to 0.17 h-1 and growth was adequately described by the Monod theory when maintenance energy requirements were considered.
(20) If parameters of the equation are estimated from the results obtained at low concentrations, then at high concentrations of nutrient, the specific growth rate is significantly higher than that predicted by Monod's equation.
Monody
Definition:
(n.) A species of poem of a mournful character, in which a single mourner expresses lamentation; a song for one voice.
Example Sentences:
(1) S. serratum stands clearly apart and the couple S. rugicauda and S. hookeri form an opposite extreme; S. monodi and S. teissieri offer some affinities.
(2) The reaction showed no dependence on magnesium or sodium ions, did not occur with other monodi-, and tri-phosphates as substrates, and was inhibited by p-chlormercuribenzoate (PCMB) and sodium fluoride, but not by ouabain.
(3) The electrophoretic analysis of lactate NAD oxydoreductase in interspecific hybrids between three species of genus Sphaeroma (S. monodi, S. rugicauda and S. hookeri hookeri) leads, for each category of hybrids, to a distribution between the two parental enzymatic patterns and, consequently, shows the absence of an isozyme appropriate to these hybrids.