(a.) Uttered in one unvarying tone; continued with dull uniformity; characterized by monotony; without change or variety; wearisome.
Example Sentences:
(1) Increasing concentrations of cholesterol monotonically increase the dipole potential of egg phosphatidylcholine monolayers, from 415 mV with no cholesterol to 493 mV with equimolar cholesterol.
(2) "Weak" subjects tended to fall asleep more rapidly during monotonous stimulation, whereas the reverse was true of "strong" subjects.
(3) Although their increases were monotonic in a given heart, their sensitivities to catecholamines were considerably variable among hearts.
(4) For an "FM specialized" cell, the response pattern to each of the parameters was either monotonic or bell-shaped.
(5) The extent of Ca2+ uptake was monotonically increased as the pH increased from 6 to 9.
(6) Serum apolipoprotein A-I concentrations were unaltered, apolipoprotein A-II underwent a transient increase, and apolipoprotein B increased monotonically during parenteral nutrition.
(7) Critical features of the model include a non-monotonic relationship between recovery time during rhythmic stimulation and the state of membrane properties, and a steeply sloped recovery of membrane properties over certain ranges of recovery times.
(8) As subcritical crack velocities under cyclic loading were found to be many orders of magnitude faster than those measured under equivalent monotonic loads and to occur at typically 45% lower stress-intensity levels, cyclic fatigue in pyrolytic carbon-coated graphite is reasoned to be a vital consideration in the design and life-prediction procedures of prosthetic devices manufactured from this material.
(9) Pulsed-field electrophoresis experiments resulting in the establishment of an electrophoretic karyotype for yeast, where the mobility of the DNA fragments is a monotonic function of molecular size for the entire size range that is resolved (200-2200 kilobase pairs), has been compared to the theoretical mobility curves generated by the computer model.
(10) Input-output functions at inhibitory frequencies were nonmonotonic, while they were always monotonic at best frequencies near CF.
(11) Other consequences of increasing gNa+max were a decrease in the minimum sustainable rhythmic firing frequency (mRFF), a monotonic increase in firing frequency at any given suprathreshold stimulus intensity, an increase in the current value at which intense depolarizing stimuli block rhythmogenesis, an increase in the maximal sustainable firing frequency using intense currents (MRFF), and the consequent expansion of the dynamic range for stimulus encoding.
(12) The voltage dependences of the ON and OFF charges measured with these pulses were clearly different: QON had a maximum at or slightly above the contraction threshold, while QOFF increased monotonically in the voltage range examined.
(13) FNA smears from a lymph node in a patient with a previous histological diagnosis of lymphomatoid papulosis of the gingiva showed a monotonous pattern of large immunoblastic cells with some binucleated variants consistent with a diagnosis of high grade immunoblastic lymphoma, which was confirmed histologically.
(14) It is a monotonous, unreactive and anteriorly predominant activity of less than 50 microV and of 8 to 13 Hz.
(15) Several temporal principles that govern multisensory integration were revealed: (1) maximal levels of response enhancement were generated by overlapping the peak discharge periods evoked by each modality; (2) the magnitude of this enhancement decayed monotonically to zero as the peak discharge periods became progressively more temporally disparate; (3) with further increases in temporal disparity, the same stimulus combinations that previously produced enhancement could often produce depression; and (4) these kinds of interactions could frequently be predicted from the discharge trains initiated by each stimulus alone.
(16) Monotonic decreases in ambulation after tetrabenazine were not significantly affected in the rubidium-treated animals though the decreases were sometimes preceded by slight increases and recovery from the decrement tended to be more rapid.
(17) To estimate mechanical characteristics of such membranes, it is necessary to carry out the noncontact pressure test and membranous contact test, in addition to the usual monotonic tensile test, by using a rectangular specimen cut from the membranes.
(18) In cell-attached recordings the high-frequency component declined monotonically with increasing light intensity, suggesting that less than one-half of the channels are open in darkness.
(19) The strength of this genetic control, however, systematically diminished throughout the course of practice obeying a monotonic trend over trials.
(20) The open time had a monotonic mole fraction relationship in mixtures of Li+ and K+.
Tedious
Definition:
(a.) Involving tedium; tiresome from continuance, prolixity, slowness, or the like; wearisome.
Example Sentences:
(1) Parties are a tedious chore, while sponsorships are pretty tiresome too: can you remember the key messaging about that motor oil you agreed to plug to the nearest reporter?
(2) Skin deepithelialization is an integral part of many reconstructive procedures, but it can be a tedious and time-consuming ordeal when using conventional techniques.
(3) The method provides an antibody reagent that is an attractive alternative to other more tedious means of producing oligospecific antibodies, including monoclonal antibodies, for screening of expression libraries.
(4) Richard Kemp, London SE8 I know I'm being tedious, but what are "American" novels?
(5) Almond lamb curry: Atul Kochhar This dish derives its main flavour from a spice blend called vadagam, which can be a little tedious to make.
(6) Its reliability and convenience represent an improvement over existing methods based on the tedious and time-consuming enzymatic radioisotopic determination of the carnitine formed or on the coupled decarboxylation of [1-14C]alpha-ketoglutarate, a method that cannot be used in crude extracts.
(7) Breathe deeply.” With the worryingly rapid rise of diagnoses in autism across the world over the past couple of decades comes another tedious phenomenon: the casual use of the word “autistic” to describe behaviour by people who, frankly, don’t know a lot about autism.
(8) One of the advantages of OK-432 therapy over lymphokine-activated killer cell therapy, therefore, is that the former does not require the tedious and time-consuming in vitro procedures which are essential for the latter.
(9) Fashion people don't mind being dismissed as "weird" – hell, "weird" is precisely what they're going for, because they're trying to show that they're different from you, you tedious River Island-shopping pleb.
(10) The workup for polyuria and polydipsia, especially in those cases with normal or near normal blood work, can be tedious, time consuming, confusing, and not without significant patient morbidity.
(11) The manual radiographic method is accurate both in normals and in patients with airways disease but is very tedious to use.
(12) These methods have several undesirable features; some are tedious and time-consuming, some remove antibody along with nonspecific inhibitors, and different techniques are usually required to remove the nonspecific inhibitors for different viruses.
(13) Austen Lynch Garstang, Lancashire • The government’s plan to turn all schools into academies suggests it has reached the same conclusion as Macbeth: “I am in blood stepped so far that, should I wade no more, returning were as tedious as go over.” Steve Loveman Sheffield • Join the debate – email guardian.letters@theguardian.com
(14) This avoids the tedious dissection involved in looking for small distal branches with their variable location.
(15) Today's techniques can produce ordered arrays of DNA fragments and overlapping sets of DNA clones covering extensive genomic regions, but they are relatively slow and tedious.
(16) Many of the spontaneous and in some cases leaderless Arab spring movements of 2011 were unsuited to taking on the tedious roles of political parties and constitutional lawyers.
(17) The technique was further simplified by using commercially available antibiotic-containing disks, thereby alleviating the tedious and time-consuming procedure of preparing the disks.
(18) A major obstacle in the application of quantitative microelectrophoresis has been tedious manipulations and calculations.
(19) The advantages of the titrimetric method include simplicity, rapidity, convenience, sensitivity, reproducibility and specificity, whereas the gravimetric method is tedious and time-consuming.
(20) Recording the required information may be tedious, but it can be carried out using either a paper-based system or its computerized equivalent.