(1) This receptor and a growing family of related cytokine receptors share homologous extracellular features, including a well-conserved WSXWS motif.
(2) We have generated a series of mutants in the two copies of this motif present in human immunodeficiency virus type 1.
(3) An additional 14 leader peptides in this collection (all of those that contain an arginine at -10) conform to this motif.
(4) In addition, region III has some structural features similar to a conserved motif found in complement receptor 1, the human C3b receptor.
(5) A new alternative splice site was incidently found 81 nucleotide downstream of motif II in both normal and truncated 4.1 mRNA.
(6) The same RNA-protein motif is used, through iron-dependent degradation of transferrin receptor mRNA, to decrease synthesis of the receptor and cellular iron uptake.
(7) Comparison of the human and mouse repeats revealed a highly conserved Glu-Asp core in each unit, implicating the functional significance of this motif.
(8) The three-dimensional solution structure of a zinc finger nucleic acid binding motif has been determined by nuclear magnetic resonance (NMR) spectroscopy.
(9) Sequence comparison programs suggested the presence of domains related to the RNA recognition motif found in other RNA-binding proteins, and deletion analysis revealed that the carboxyl-terminal 195 amino acids of the recombinant PTB was sufficient for specific binding to pre-mRNAs.
(10) Since similar loop conformations form similar "words", the structural sequence facilitates the search for common structural motifs in a family of loops.
(11) A new repetitive DNA region was identified in the non-transcribed spacer of human rDNA, namely a long (4.6 kb) sequence motif (Xbal element) was present in two copies.
(12) X-ray analysis of these crystals will permit direct visualization of the specific structural motifs and chemical features that underlie phospholipase neurotoxicity.
(13) Information about the three-dimensional structure or function of a newly determined protein sequence can be obtained if the protein is found to contain a characterized motif or pattern of residues.
(14) For PPD-specific TCCs, a possible biased usage of V beta 8, as well as possible preferential usage of a CDR3 motif, were found.
(15) This phenomenon was observed by using wheat-germ RNA polymerase II and a series of double-stranded template polymers containing palindromic repeating motifs of 6-16 bp, with regulatory alternating purine and pyrimidine bases such as d[ATA(CG)nC].d[TAT(GC)nG], with n = 1, 3 or 6 referred to as d(GC), d(GC)3 or d(GC)6, respectively.
(16) A sequence between residues 302 and 320 homologous to a metal-binding "finger" motif is therefore not required for origin-specific binding.
(17) In this report, we examined the functional significance of these six motifs for the UL9 protein through the introduction of site-specific mutations resulting in single amino acid substitutions of the most highly conserved residues within each motif.
(18) These sequences have a number of similar motifs at, or immediately following, the end of the coding regions, motifs that may be involved in their S mRNA transcription termination processes.
(19) The TV campaign, created by ad agency Leo Burnett, uses imagery and motifs more closely associated with Christmas than summer.
(20) Interestingly, the helical motif prefers to assemble parallel to the wall, whereas the beta-barrel, predominantly assembles with its principal axis perpendicular to the wall.
Motive
Definition:
(n.) That which moves; a mover.
(n.) That which incites to action; anything prompting or exciting to choise, or moving the will; cause; reason; inducement; object.
(n.) The theme or subject; a leading phrase or passage which is reproduced and varied through the course of a comor a movement; a short figure, or melodic germ, out of which a whole movement is develpoed. See also Leading motive, under Leading.
(n.) That which produces conception, invention, or creation in the mind of the artist in undertaking his subject; the guiding or controlling idea manifested in a work of art, or any part of one.
(a.) Causing motion; having power to move, or tending to move; as, a motive argument; motive power.
(v. t.) To prompt or incite by a motive or motives; to move.
Example Sentences:
(1) The authors empirically studied the self-medication hypothesis of drug abuse by examining drug effects and motivation for drug use in 494 hospitalized drug abusers.
(2) As important providers of health care education, nurses need to be fully informed of the research findings relevant to effective interventions designed to motivate health-related behavior change.
(3) These findings raise questions regarding the efficacy of medical school curriculum in motivating career choices in primary care.
(4) If there is a will to use primary Care centres for effective preventive action in the population as a whole, motivation of the professionals involved and organisational changes will be necessary so as not to perpetuate the law of inverse care.
(5) He stressed the importance of the motivation to the mother for breast feeding and the independence between levels of instruction and frequency of breast feeding.
(6) The charges against Harrison were filed just after two white men were accused of fatally shooting three black people in Tulsa in what prosecutors said were racially motivated attacks.
(7) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(8) Gwendolen Morgan, the lawyer at Bindmans dealing with the case, said: "We have grave concerns about the decision to use this draconian power to detain our client for nine hours on Sunday – for what appear to be highly questionable motives, which we will be asking the high court to consider.
(9) The decision to an orthodontic treatment was led by esthetic and functional motives.
(10) That motivation is echoed by Nicola Saunders, 25, an Edinburgh University graduate who has just been called to the bar to practise as a barrister and is tutoring Moses, an ex-convict, in maths.
(11) Three motives are found for evaluating the quality of human life: allocation of scarce medical resources, facilitating clinical decision making, and assisting patients towards autonomous decision making.
(12) The hypothesis that metabolic rate, as well as foraging and recruiting activities, depend on the motivational state of the foraging bee determined by the reward at the food source is discussed.
(13) The results may be due to stronger social reinstatement tendencies in females than in males: Higher levels of social motivation facilitate behavioral performance when the task is easy (straight runway) and inhibit it when the task is difficult (V-shaped runway).
(14) The ATPase inhibitor dicyclohexylcarbodiimide, which collapsed the chemical and electrical components of the proton motive force, caused rapid cell swelling in the presence of glucose (and high intracellular ATP levels).
(15) The precondition for cooperation is intensive medical advice covering the following three aspects: 1. education, 2. motivation to put the acquired knowledge into practice, 3. practicability of the advice given.
(16) This, along with evidence that kinesin is associated with the endoplasmic reticulum, has led to the suggestion that kinesin provides the motive force for the formation and maintenance of elongated tubulovesicular structures in cells.
(17) Scores on the "dependent smoking" subscale of the smoking motivation questionnaire correlated significantly with overall withdrawal severity, craving, and increased irritability.
(18) Other factors that may have important effects on recovery include the localization, nature, extension and degree of brain damage, the patient's sex and age, the duration of coma, the patient's original cognitive capacity, his personality and motivation as well as the duration and intensity of rehabilitation and the time before starting rehabilitation.
(19) So when did audiences become so deferential to a release strategy blatantly motivated by naked financial gain?
(20) The major findings were that the test group improved their running time and had better sport motivation than did the control group, and there were differences between boys and girls and an influence of sexual maturation on running time in girls.