(1) This receptor and a growing family of related cytokine receptors share homologous extracellular features, including a well-conserved WSXWS motif.
(2) We have generated a series of mutants in the two copies of this motif present in human immunodeficiency virus type 1.
(3) An additional 14 leader peptides in this collection (all of those that contain an arginine at -10) conform to this motif.
(4) In addition, region III has some structural features similar to a conserved motif found in complement receptor 1, the human C3b receptor.
(5) A new alternative splice site was incidently found 81 nucleotide downstream of motif II in both normal and truncated 4.1 mRNA.
(6) The same RNA-protein motif is used, through iron-dependent degradation of transferrin receptor mRNA, to decrease synthesis of the receptor and cellular iron uptake.
(7) Comparison of the human and mouse repeats revealed a highly conserved Glu-Asp core in each unit, implicating the functional significance of this motif.
(8) The three-dimensional solution structure of a zinc finger nucleic acid binding motif has been determined by nuclear magnetic resonance (NMR) spectroscopy.
(9) Sequence comparison programs suggested the presence of domains related to the RNA recognition motif found in other RNA-binding proteins, and deletion analysis revealed that the carboxyl-terminal 195 amino acids of the recombinant PTB was sufficient for specific binding to pre-mRNAs.
(10) Since similar loop conformations form similar "words", the structural sequence facilitates the search for common structural motifs in a family of loops.
(11) A new repetitive DNA region was identified in the non-transcribed spacer of human rDNA, namely a long (4.6 kb) sequence motif (Xbal element) was present in two copies.
(12) X-ray analysis of these crystals will permit direct visualization of the specific structural motifs and chemical features that underlie phospholipase neurotoxicity.
(13) Information about the three-dimensional structure or function of a newly determined protein sequence can be obtained if the protein is found to contain a characterized motif or pattern of residues.
(14) For PPD-specific TCCs, a possible biased usage of V beta 8, as well as possible preferential usage of a CDR3 motif, were found.
(15) This phenomenon was observed by using wheat-germ RNA polymerase II and a series of double-stranded template polymers containing palindromic repeating motifs of 6-16 bp, with regulatory alternating purine and pyrimidine bases such as d[ATA(CG)nC].d[TAT(GC)nG], with n = 1, 3 or 6 referred to as d(GC), d(GC)3 or d(GC)6, respectively.
(16) A sequence between residues 302 and 320 homologous to a metal-binding "finger" motif is therefore not required for origin-specific binding.
(17) In this report, we examined the functional significance of these six motifs for the UL9 protein through the introduction of site-specific mutations resulting in single amino acid substitutions of the most highly conserved residues within each motif.
(18) These sequences have a number of similar motifs at, or immediately following, the end of the coding regions, motifs that may be involved in their S mRNA transcription termination processes.
(19) The TV campaign, created by ad agency Leo Burnett, uses imagery and motifs more closely associated with Christmas than summer.
(20) Interestingly, the helical motif prefers to assemble parallel to the wall, whereas the beta-barrel, predominantly assembles with its principal axis perpendicular to the wall.
Passage
Definition:
(v. i.) The act of passing; transit from one place to another; movement from point to point; a going by, over, across, or through; as, the passage of a man or a carriage; the passage of a ship or a bird; the passage of light; the passage of fluids through the pores or channels of the body.
(v. i.) Transit by means of conveyance; journey, as by water, carriage, car, or the like; travel; right, liberty, or means, of passing; conveyance.
(v. i.) Price paid for the liberty to pass; fare; as, to pay one's passage.
(v. i.) Removal from life; decease; departure; death.
(v. i.) Way; road; path; channel or course through or by which one passes; way of exit or entrance; way of access or transit. Hence, a common avenue to various apartments in a building; a hall; a corridor.
(v. i.) A continuous course, process, or progress; a connected or continuous series; as, the passage of time.
(v. i.) A separate part of a course, process, or series; an occurrence; an incident; an act or deed.
(v. i.) A particular portion constituting a part of something continuous; esp., a portion of a book, speech, or musical composition; a paragraph; a clause.
(v. i.) Reception; currency.
(v. i.) A pass or en encounter; as, a passage at arms.
(v. i.) A movement or an evacuation of the bowels.
(v. i.) In parliamentary proceedings: (a) The course of a proposition (bill, resolution, etc.) through the several stages of consideration and action; as, during its passage through Congress the bill was amended in both Houses. (b) The advancement of a bill or other proposition from one stage to another by an affirmative vote; esp., the final affirmative action of the body upon a proposition; hence, adoption; enactment; as, the passage of the bill to its third reading was delayed.
Example Sentences:
(1) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(2) Exposure to nanomolar concentrations of saralasin, an Ang II agonist, attenuated the passage of the fluorophores across the monolayers by 50-75%.
(3) Cultured cells from fourth to ninth passage showed positive labelling for S 100 protein, carbonic anydrase (CAA), glutamine synthetase (GS), alpha cristallin (alpha C) and polyclonal glial fibrillary acidic protein (GFAP) antibody, but were negative for both monoclonal GFAP antibody and also for Muller cells in the retina.
(4) In the case of the latter, it show either a more or less typical appearance of radicolography only or, more rarely, a picture which combines opacification of the epidural space with the subarachnoid passage of the contrast medium.
(5) After approximately 20 in vitro passages, Chinese hamster kidney (CHK) cell cultures transformed upon exposure to different strains of SV 40 can show a diploid modal chromosome number of 22 with chromosome counts exclusively or essentially in the diploid range (20-25).
(6) In late-passage and cloned HUT102 cells, an increase in HTLV production was concordant with a decrease in constitutive interferon production and the loss of mature T lymphocyte antigens.
(7) A reduction of salmonellae during the passage of the pump and pressure conduit-pipe, combining east- and west-side of Kiel fjord, could be seen.
(8) The resulting cell lines have a stable phenotype and retain the changes which result from transformation even after extended passaging.
(9) Abe’s longstanding efforts toward those goals, which include the successful passage of a state secrets act and efforts to expand the scope of Japan’s military activities have already damaged relations with China.
(10) It is inferred that in this experimental model (1) high-density lipoproteins are probably excreted in the glomerular filtrate, (2) alterations in the composition of the excreted lipoproteins may occur during their passage through the nephron.
(11) We report that kainic acid lesions of the posterior corpus striatum, which preferentially spare fibers of passage while destroying striatopallidal neurons, produce a stimulus-sensitive movement pattern in rats that has a highly specific sensory trigger.
(12) The cells have been maintained through 23 serial passages, and the modal number of chromosomes was calculated to be 55.
(13) The rate of passage of digesta was significantly reduced in both pair-fed control (50 per cent) and infected (74 per cent) groups.
(14) Unlike cells grown on plastic, RME cells grown on type I collagen were readily subculturable and serial subculture resulted in the cells undergoing 15-20 population doublings (5-6 passages) before exhibiting any loss of growth potential.
(15) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
(16) In addition, SPT16 is identical to CDC68, a gene previously shown to be required for passage through the cell cycle control point START.
(17) Selective catheterisation enabled opacification under pressure in more than 80 p. cent of cases, with perfect visualisation of the entire tubes and significant peritoneal passage.
(18) The effects of Urocalun and jumping exercise upon the passage of calculi were studied.
(19) The alterations in the glycosaminoglycans and collagen induced by hypoxia may cause changes in the passage of macromolecules through the aortic wall.
(20) Despite the lack of expression of the endogenous CYP17 gene in transfectants from late-passage cells, induced luciferase activity was higher in late-passage transfectants than early-passage transfectants for both the -2544 and -488 constructs.