(1) This receptor and a growing family of related cytokine receptors share homologous extracellular features, including a well-conserved WSXWS motif.
(2) We have generated a series of mutants in the two copies of this motif present in human immunodeficiency virus type 1.
(3) An additional 14 leader peptides in this collection (all of those that contain an arginine at -10) conform to this motif.
(4) In addition, region III has some structural features similar to a conserved motif found in complement receptor 1, the human C3b receptor.
(5) A new alternative splice site was incidently found 81 nucleotide downstream of motif II in both normal and truncated 4.1 mRNA.
(6) The same RNA-protein motif is used, through iron-dependent degradation of transferrin receptor mRNA, to decrease synthesis of the receptor and cellular iron uptake.
(7) Comparison of the human and mouse repeats revealed a highly conserved Glu-Asp core in each unit, implicating the functional significance of this motif.
(8) The three-dimensional solution structure of a zinc finger nucleic acid binding motif has been determined by nuclear magnetic resonance (NMR) spectroscopy.
(9) Sequence comparison programs suggested the presence of domains related to the RNA recognition motif found in other RNA-binding proteins, and deletion analysis revealed that the carboxyl-terminal 195 amino acids of the recombinant PTB was sufficient for specific binding to pre-mRNAs.
(10) Since similar loop conformations form similar "words", the structural sequence facilitates the search for common structural motifs in a family of loops.
(11) A new repetitive DNA region was identified in the non-transcribed spacer of human rDNA, namely a long (4.6 kb) sequence motif (Xbal element) was present in two copies.
(12) X-ray analysis of these crystals will permit direct visualization of the specific structural motifs and chemical features that underlie phospholipase neurotoxicity.
(13) Information about the three-dimensional structure or function of a newly determined protein sequence can be obtained if the protein is found to contain a characterized motif or pattern of residues.
(14) For PPD-specific TCCs, a possible biased usage of V beta 8, as well as possible preferential usage of a CDR3 motif, were found.
(15) This phenomenon was observed by using wheat-germ RNA polymerase II and a series of double-stranded template polymers containing palindromic repeating motifs of 6-16 bp, with regulatory alternating purine and pyrimidine bases such as d[ATA(CG)nC].d[TAT(GC)nG], with n = 1, 3 or 6 referred to as d(GC), d(GC)3 or d(GC)6, respectively.
(16) A sequence between residues 302 and 320 homologous to a metal-binding "finger" motif is therefore not required for origin-specific binding.
(17) In this report, we examined the functional significance of these six motifs for the UL9 protein through the introduction of site-specific mutations resulting in single amino acid substitutions of the most highly conserved residues within each motif.
(18) These sequences have a number of similar motifs at, or immediately following, the end of the coding regions, motifs that may be involved in their S mRNA transcription termination processes.
(19) The TV campaign, created by ad agency Leo Burnett, uses imagery and motifs more closely associated with Christmas than summer.
(20) Interestingly, the helical motif prefers to assemble parallel to the wall, whereas the beta-barrel, predominantly assembles with its principal axis perpendicular to the wall.
Pattern
Definition:
(n.) Anything proposed for imitation; an archetype; an exemplar; that which is to be, or is worthy to be, copied or imitated; as, a pattern of a machine.
(n.) A part showing the figure or quality of the whole; a specimen; a sample; an example; an instance.
(n.) Stuff sufficient for a garment; as, a dress pattern.
(n.) Figure or style of decoration; design; as, wall paper of a beautiful pattern.
(n.) Something made after a model; a copy.
(n.) Anything cut or formed to serve as a guide to cutting or forming objects; as, a dressmaker's pattern.
(n.) A full-sized model around which a mold of sand is made, to receive the melted metal. It is usually made of wood and in several parts, so as to be removed from the mold without injuring it.
(v. t.) To make or design (anything) by, from, or after, something that serves as a pattern; to copy; to model; to imitate.
(v. t.) To serve as an example for; also, to parallel.
Example Sentences:
(1) The patterns observed were: clusters of granules related to the cell membrane; positive staining localized to portions of the cell membrane, and, less commonly, the whole cell circumference.
(2) This paper discusses the typical echocardiographic patterns of a variety of important conditions concerning the mitral valve, the left ventricle, the interatrial and interventricular septum as well as the influence of respiration on the performance of echocardiograms.
(3) A change in the pattern of care of children with IDDM, led to a pronounced decrease in hospital use by this patient group.
(4) These eight large plasmids had indistinguishable EcoRI restriction patterns.
(5) Participants (n=165) entering a week-long outpatient education program completed a protocol measuring self-care patterns, glycosylated hemoglobin levels, and emotional well-being.
(6) The pattern of the stressor that causes a change in the pitch can be often identified only tentatively, if there is no additional information.
(7) The nuclear origin of the Ha antigen was confirmed by the speckled nuclear immunofluorescence staining pattern given by purified antibody to Ha obtained from a specific immune precipitate.
(8) The subcellular distribution of sialyltransferase and its product of action, sialic acid, was investigated in the undifferentiated cells of the rat intestinal crypts and compared with the pattern observed in the differentiated cells present in the surface epithelium.
(9) The histological pattern of tumor was identified in 28 cases.
(10) We evaluated the circadian pattern of gastric acidity by prolonged intraluminal pHmetry in 15 "responder" and 10 "nonresponder" duodenal ulcer patients after nocturnal administration of placebo, ranitidine, and famotidine.
(11) In the presence of insulin, a qualitatively similar pattern of increasing responses to albumin is observed; the enhancement of each response by insulin is, however, only slightly potentiated by higher albumin concentrations.
(12) It was the purpose of the present study to describe the normal pattern of the growth sites of the nasal septum according to age and sex by histological and microradiographical examination of human autopsy material.
(13) Together these observations suggest that cytotactin is an endogenous cell surface modulatory protein and provide a possible mechanism whereby cytotactin may contribute to pattern formation during development, regeneration, tumorigenesis, and wound healing.
(14) The significance of the differences in these two patterns of actin is discussed in terms of differences in the accommodative ability and static lens shape in these two animals.
(15) Chromatographic maps of DNA adducts demonstrated unique patterns of DNA adducts for each of the regions.
(16) A triphasic pattern was evident for the neck moments including a small phase which represented a seating of the headform on the nodding blocks of the uppermost ATD neck segment, and two larger phases of opposite polarity which represented the motion of the head relative to the trunk during the first 350 ms after impact.
(17) In the upper limb and facial forms of familial amyloidotic polyneuropathy first recorded in Swiss and Finns respectively, the differences in their patterns of neurological disease and ocular lesions could be the result of their amyloids deriving from proteins other than prealbumin.
(18) A murine keratinocyte cell line that is resistant to the growth-inhibitory effects of transforming growth factor beta 1 (TGF beta 1) was examined for differential gene expression patterns that may be related to the mechanism of the loss of TGF beta 1 responsiveness.
(19) The pattern and intensity were followed up for up to 15 days.
(20) LH and FSH levels in the group which were given low dose progesterone only, rose consistently after BSO and these patterns were similar to those seen in the control group.