(n.) Any one of numerous species of small rodents belonging to the genus Mus and various related genera of the family Muridae. The common house mouse (Mus musculus) is found in nearly all countries. The American white-footed, or deer, mouse (Hesperomys leucopus) sometimes lives in houses. See Dormouse, Meadow mouse, under Meadow, and Harvest mouse, under Harvest.
(n.) A knob made on a rope with spun yarn or parceling to prevent a running eye from slipping.
(n.) Same as 2d Mousing, 2.
(n.) A familiar term of endearment.
(n.) A dark-colored swelling caused by a blow.
(n.) A match used in firing guns or blasting.
(v. i.) To watch for and catch mice.
(v. i.) To watch for or pursue anything in a sly manner; to pry about, on the lookout for something.
(v. t.) To tear, as a cat devours a mouse.
(v. t.) To furnish with a mouse; to secure by means of a mousing. See Mouse, n., 2.
Example Sentences:
(1) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
(2) BL6 mouse melanoma cells lack detectable H-2Kb and had low levels of expression of H-2Db Ag.
(3) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(4) Serial sections of mouse foetal liver, during the 9th and 16th days of gestation, were studied.
(5) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(6) 10D1 mAb induced a substantial proliferation of peripheral blood T cells when cross-linked with goat anti-mouse Ig antibody.
(7) The effects of in vivo administration of native prostaglandin E2 (PGE) on the cycling status of the granulocyte-monocyte progenitor cell (CFU-GM) were examined in a mouse model.
(8) The increase in red blood cell mass was associated with an elevation in erythropoietic stimulatory activity in serum, pleural fluid, and tumor-cyst fluid as determined by the exhypoxic polycythemic mouse assay.
(9) Implantation of the mouse embryo involves the invasion of the secondary trophoblast giant cells of the ectoplacental cone (EPC) into the uterine decidua.
(10) It is concluded that in the mouse model the ability of buspirone to reduce the aversive response to a brightly illuminated area may reflect an anxiolytic action, that the dorsal raphe nucleus may be an important locus of action, and that the effects of buspirone may reflect an interaction at 5-hydroxytryptamine receptors.
(11) The expression of the mRNA for mouse testicular lactate dehydrogenase (LDH-X) was examined by RNA:cDNA hybridization in situ in the testis and by Northern analyses of meiotic and postmeiotic spermatogenic cell populations.
(12) These results provide evidence that trait selection can change gonadotrophin receptor concentration and the dynamics of hormone secretion during the oestrous cycle of the mouse.
(13) In the triploids, the 40 female chromosomes present (mouse, n = 20) were derived from a single diploid pronucleus formed after the extrusion of a first polar body, and following the monospermic fertilization of primary oocytes.
(14) These results do not support the view that in the rat pheromones from adult males enhance puberty in females, contrary to what is known to happen in the mouse.
(15) Stable factor-dependent B-cell hybridomas were used to monitor the purification of the growth factor from the supernatant of a clonotypically stimulated mouse helper T-cell clone.
(16) Human GH did not alter basal cyclic AMP levels in mouse osteoblasts.
(17) DNA from 9% (47 of 529) of the E. coli colonies tested hybridized with the ST probe, whereas only 5% (28 of 529) produced ST as measured by the suckling mouse bioassay.
(18) We previously established that the binding constant (Ka) of this receptor site for the chemically synthesized model AGE, 2-(2-furoyl)-4(5)-(2-furanyl)-1H- imidazole-butyric acid (FFI-BA), on cells of the mouse macrophagelike cell line RAW 264.7 is identical to that for AGE proteins.
(19) The nature, intracellular distribution, and role of proteins synthesized during meiotic maturation of mouse oocytes in vitro have been examined.
(20) The relative contributions of transcriptional and posttranscriptional regulation of gene expression to the increase in constitutively expressed cellular proteins were examined in mouse kidneys undergoing compensatory growth following unilateral nephrectomy (UNI-NX).
Reeler
Definition:
(n.) One who reels.
(n.) The grasshopper warbler; -- so called from its note.
Example Sentences:
(1) Although the reeler, an autosomal recessive mutant mouse with the abnormality of lamination in the central nervous system, died about 3 weeks of age when fed ordinary laboratory chow, this mouse could grow up normally and prolong its destined, short lifespan to 50 weeks and more when given assistance in taking paste food and water from the weaning period.
(2) The metabolism of 5-hydroxytryptamine (5-HT) in the CNS was investigated in four kinds of morphologically different ataxic mice; reeler, staggerer, weaver and Purkinje cell degeneration mutants, and in hypocerebellar mice experimentally produced by injection of cytosine arabinoside.
(4) Reeler is an autosomal recessive mutation of mice that alters neuronal migration during development, yielding a general inversion of the laminae in the neocortex.
(5) Unlike dissociated hippocampal pyramidal cells, which frequently resemble their in vivo morphology, dissociated dentate granule cells bear little resemblance to their normal in vivo counterparts, but are very similar in appearance to the ectopic granule cells seen in the reeler mouse.
(6) Although we cannot determine whether the Purkinje cell loss in reeler is a primary or secondary gene effect, the possibility that the reeler gene has its effect on migration through a primary effect on neurogenesis or cell survival should be considered.
(7) The reeler cerebellum, which possesses an abnormal cytoarchitecture with numerous ectopically located Purkinje cells, was stained histochemically for the presence of 5'-nucleotidase.
(8) The distribution of the perikarya of astrocytes and other glial cells in the molecular layer of the dentate gyrus has been studied in gold chloride-sublimate preparations of rats and of normal and reeler mice, and in plastic embedded material from young adult rats.
(9) Nevertheless, while SS fibers in the normal cortex are most dense in layers I and V-VI, the reeler cortex exhibits little laminar heterogeneity in the distribution of these fibers.
(10) These comparative observations in normal and reeler mutant mice lend support to previous suggestions that L1, together with N-CAM, may play a role in the aggregation of neuronal cell bodies after migration and in the fasciculation of developing fiber bundles.
(11) This suggests that cell differentiation and the tangenital organization of reeler neocortex are normal despite cell malposition in the mutant.
(12) The specific content of P400 protein decreases in the cerebella from homozygous nervous and Purkinje cell degeneration mutant mice, where the total number of Purkinje cells is markedly reduced, and increases in those of the reeler and weaver mice where a deficit of the granule cells exists.
(13) Bergmann fibers and the distribution of Golgi epithelial cells were significantly altered in staggerer, reeler and double mutant (affected by both staggerer and reeler conditions).
(14) On the other hand, anomalies of Purkinje cells and Bergmann fibers, which are also present both in staggerer and reeler, did not follow the same additive change.
(15) However, in the reeler dentate gyrus, most postnatal cell proliferation occurs ectopically and in the hippocampus the normal "inside-out" sequence of neurogenesis is reversed, the earliest pyramidal cells generated coming to lie superficially within the stratum pyramidale and the later formed cells being added at progressively deeper levels.
(16) We performed a descriptive analysis on the arborization of dendritic processes of large pyramidal neurons in the motor cortex (hindlimb area) of normal and reeler mice, as seen in the Golgi preparations.
(17) In reeler, by contrast, fascicles of retinotectal axons are distributed through the entire thickness of SGS as well as through SO.
(18) It is evident from both cell-and fiber-stained sections that despite the obvious defect in the positioning of the hippocampal pyramidal and dentate granule cells in the reeler mouse within the radial dimension, the hippocampal formation as a whole shows a normal and consistent progression of cytoarchitectonic fields along its transverse axis, and a normal and consistent progression of changes in the structure of the hippocampus and dentate gyrus along their longitudinal axes.
(19) The characterization and thus the cloning of the reeler gene is therefore important for our understanding of brain development.
(20) The apical dendrites of the CC neurons in all layers of the cortex of the reeler mouse are randomly oriented; no direct relationship between the intracortical position of the soma and orientation of the apical dendrite was found.