(a.) Containing many nuclei; as, multinuclear cells.
Example Sentences:
(1) In the synovia, size and number of the multinuclear giant cells are less pronounced.
(2) The multinuclear giant cells (MGCs) with undegenerating nuclei migrating from the explants had active ameboid movement and continuously changed their shapes.
(3) The increase in the CG beta mRNA with cell size is a consequence of the transcriptional mechanism, since agents which induce differentiation in JAr cells, i.e., methotrexate, increase the level of CG alpha and CG beta transcripts, cause a shift in cell size, and result in the formation of multinuclear cells.
(4) In multinuclear clusters cysteine thiolates either bridge two metal ions or serve as terminal ligands to a single metal ion.
(5) From these results, it is reasonable to conclude that Kupffer cells alone are activated in a condition without a supply of monocytes from peripheral blood; proliferate and cluster in the hepatic sinusoids; transform into peroxidase-negative macrophages, epithelioid cells, and multinuclear giant cells; and participate in granuloma formation in loco together with T lymphocytes.
(6) A15A5 cells became bipolar, developed longer processes and produced less extracellular fibronectin, whereas ARBOC9 cells became enlarged, showed increased multinuclearity, expressed more fibronectin and contained actin-like cytoplasmic filaments.
(7) Heavy mononuclear inflammatory interstitial infiltration, with granulomatous structures including giant multinuclear cells as those seen in foreign body reactions (fig 1) and PAS positive intraluminal tubular crystals were also observed.
(8) The cytological effects observable both in vivo and in vitro on different plant and animal cell systems, include C-mitoses, multipolar mitoses and multinuclearity.
(9) The stability constants have also been determined by multinuclear n.m.r.
(10) Third, mezerein and teleocidin, nonphorbol ester tumor promotors, also induce development of multinuclearity and polyploidy.
(11) Complexes of contacting epithelioid cells are one of the sources of multinuclear giant cells.
(12) We observed mononuclear cells as preosteoclasts and multinuclear cells with and without ruffled borders (RB).
(13) The results of this multinuclear NMR approach are discussed in terms of metabolic responses of C6 cells to beta-adrenergic stimulation and cAMP overproduction.
(14) Both uninuclear cells and multinuclear tubes contained numerous lysosomes, myelin figures and lamellated bodies as well as electronlucent or content-filled vacuoles and cisternae of variable size, sometimes reminding the sarcoplasmic reticulum in early stages of its development.
(15) Multinuclear giant cells and macrophages were the predominant cell types in the porosity of the Plastipore implants.
(16) Multinuclear NMR analysis is used to analyze photoproduct formation and to determine conformational features of these photodimers.
(17) Details of their presence and experimental induction as well as their distinction into a number of morphological types, including multinuclear (giant cell) forms, is described in this communication.
(18) Embryonic rhabdomyogenesis is imitated most perfectly by subpopulation C, in which multinuclear myotubes are formed in vitro by fusion of mononuclear cells, and alpha-sarcomeric actin is expressed in the multinuclear cells and in a few mononuclear cells.
(19) The ability to localize precisely defined volumes of interest within tissue with measurement of multinuclear magnetic resonance spectra (1H and 31P) has provided a basis for integrating spectroscopy into the clinical MRI examination.
(20) In contrast, the synthetic capacity of these proteins seemed not to correspond with the morphological change in extravillous trophoblasts: The location of hCG alpha, hCG beta CTP and SP1 was restricted to the mononuclear trophoblasts in the superficial decidua, while hPL was present extensively in extravillous trophoblasts, including multinuclear trophoblasts in the deciduomuscular junction.
Multinucleate
Definition:
(a.) Alt. of Multinucleated
Example Sentences:
(1) High degress of multinucleation were observed least frequenctly in the summer both in patients with and without known malignancy.
(2) Patients with malignant disease are known to have an increased incidence of multinucleation in their tracheobronchial ciliated epithelial cells as compared with controls matched by age, sex and smoking habit.
(3) We have previously shown that multinucleated cells (MNC) with many features of the osteoclast phenotype form in long term human marrow cultures.
(4) When we compare the duration of G1, S and G2 periods in diploid cells with that obtained for multinucleate cells in the present study it seems clear that the differences, if they occur, are negligible.
(5) After induction of myogenic differentiation by treatments with excess thymidine and conditioned medium, two clones were capable of forming short multinucleated cells.
(6) The FNA cytologic findings included markedly atypical fibroblast-like cells lying singly and in groups in a myxoid background, highly atypical multinucleated cells and numerous mitoses, features that were interpreted as a high-grade malignant mesenchymal tumor.
(7) They proceed through meiosis normally, as judged by the occurrence of meiotic recombination, the production of haploid nuclei, and the formation of multinucleate cells visible after Giemsa staining.
(8) Histopathological examination of the nodules revealed features typical for SFNN: lobular panniculitis with fat necrosis and radiating needle-shaped clefts within multinucleated histiocytes.
(9) The incidence of multinucleated spermatids may be increased by stress associated with handling or the environment.
(10) Subacute encephalitis with white matter lesions and multinucleated giant cells characteristic of HIV infection was present in 15 cases.
(11) The cell shape varied greatly and included dendritic, stellated and strap-shaped forms as well as multinucleated giant cells, similar to those of juvenile melanomatas.
(12) The macrophages in the lung tissue showed the same changes and in addition nodules of multinucleated "giant" cells were found.
(13) Features of HPV infection (koilocytosis, binucleation, multinucleation, giant irregular nuclei and individual cell dyskeratosis) were present in high prevalence in both HPV 6 and HPV 16 associated CIN.
(14) The mononuclear phagocytic system is a continuum of cells beginning with the bone marrow monoblast and promonocyte, through the monocyte to the larger tissue macrophages and multinucleate giant cells.
(15) Epithelioid-cell tumors contained multinucleated cells and areas of cell wrapping more frequently than did spindle-cell tumors.
(16) Type I beads: at 3 days, were surrounded by multinucleated giant cells; by 4 days, patches of bead-associated new bone were present along with giant cells; after 1 week, occasional bead-associated multinucleated cells were seen, but now most beads were surrounded by new intramedullary bone, forming an extensive bead-bone lattice.
(17) The most characteristic morphological feature of the CMV-infected BAMB cells was the formation of multinucleated giant cells which frequently contained more than a hundred nuclei; such cells were not seen in LEP cultures.
(18) Adult Wistar rats were bilaterally caput epididymectomized and the effects on testicular germinal epithelium and formation of multinucleated bodies were studied and quantified at 2, 4, 7, 14, 21, and 28 days after surgery.
(19) In situ hybridization for HIV-1 nucleic acid sequences gave positive results in seven of 18 spinal cords, with hybridizing signal usually localized to inflammatory cell infiltrates and multinucleated cells.
(20) All of the multinucleated cells were found to have a similar arragnement of nuclear concentration areas and nucleus-free areas.