(1) High degress of multinucleation were observed least frequenctly in the summer both in patients with and without known malignancy.
(2) Patients with malignant disease are known to have an increased incidence of multinucleation in their tracheobronchial ciliated epithelial cells as compared with controls matched by age, sex and smoking habit.
(3) We have previously shown that multinucleated cells (MNC) with many features of the osteoclast phenotype form in long term human marrow cultures.
(4) When we compare the duration of G1, S and G2 periods in diploid cells with that obtained for multinucleate cells in the present study it seems clear that the differences, if they occur, are negligible.
(5) After induction of myogenic differentiation by treatments with excess thymidine and conditioned medium, two clones were capable of forming short multinucleated cells.
(6) The FNA cytologic findings included markedly atypical fibroblast-like cells lying singly and in groups in a myxoid background, highly atypical multinucleated cells and numerous mitoses, features that were interpreted as a high-grade malignant mesenchymal tumor.
(7) They proceed through meiosis normally, as judged by the occurrence of meiotic recombination, the production of haploid nuclei, and the formation of multinucleate cells visible after Giemsa staining.
(8) Histopathological examination of the nodules revealed features typical for SFNN: lobular panniculitis with fat necrosis and radiating needle-shaped clefts within multinucleated histiocytes.
(9) The incidence of multinucleated spermatids may be increased by stress associated with handling or the environment.
(10) Subacute encephalitis with white matter lesions and multinucleated giant cells characteristic of HIV infection was present in 15 cases.
(11) The cell shape varied greatly and included dendritic, stellated and strap-shaped forms as well as multinucleated giant cells, similar to those of juvenile melanomatas.
(12) The macrophages in the lung tissue showed the same changes and in addition nodules of multinucleated "giant" cells were found.
(13) Features of HPV infection (koilocytosis, binucleation, multinucleation, giant irregular nuclei and individual cell dyskeratosis) were present in high prevalence in both HPV 6 and HPV 16 associated CIN.
(14) The mononuclear phagocytic system is a continuum of cells beginning with the bone marrow monoblast and promonocyte, through the monocyte to the larger tissue macrophages and multinucleate giant cells.
(15) Epithelioid-cell tumors contained multinucleated cells and areas of cell wrapping more frequently than did spindle-cell tumors.
(16) Type I beads: at 3 days, were surrounded by multinucleated giant cells; by 4 days, patches of bead-associated new bone were present along with giant cells; after 1 week, occasional bead-associated multinucleated cells were seen, but now most beads were surrounded by new intramedullary bone, forming an extensive bead-bone lattice.
(17) The most characteristic morphological feature of the CMV-infected BAMB cells was the formation of multinucleated giant cells which frequently contained more than a hundred nuclei; such cells were not seen in LEP cultures.
(18) Adult Wistar rats were bilaterally caput epididymectomized and the effects on testicular germinal epithelium and formation of multinucleated bodies were studied and quantified at 2, 4, 7, 14, 21, and 28 days after surgery.
(19) In situ hybridization for HIV-1 nucleic acid sequences gave positive results in seven of 18 spinal cords, with hybridizing signal usually localized to inflammatory cell infiltrates and multinucleated cells.
(20) All of the multinucleated cells were found to have a similar arragnement of nuclear concentration areas and nucleus-free areas.
Nucleus
Definition:
(n.) A kernel; hence, a central mass or point about which matter is gathered, or to which accretion is made; the central or material portion; -- used both literally and figuratively.
(n.) The body or the head of a comet.
(n.) An incipient ovule of soft cellular tissue.
(n.) A whole seed, as contained within the seed coats.
(n.) A body, usually spheroidal, in a cell or a protozoan, distinguished from the surrounding protoplasm by a difference in refrangibility and in behavior towards chemical reagents. It is more or less protoplasmic, and consists of a clear fluid (achromatin) through which extends a network of fibers (chromatin) in which may be suspended a second rounded body, the nucleolus (see Nucleoplasm). See Cell division, under Division.
(n.) The tip, or earliest part, of a univalve or bivalve shell.
(n.) The central part around which additional growths are added, as of an operculum.
(n.) A visceral mass, containing the stomach and other organs, in Tunicata and some mollusks.
Example Sentences:
(1) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(2) The present results provide no evidence for a clear morphological substrate for electrotonic transmission in the somatic efferent portion of the primate oculomotor nucleus.
(3) In the caudal spinal trigeminal nucleus (Vc), the collaterals of one half of the periodontium afferent fibers terminated mainly in lamina V at the rostral and middle levels of Vc.
(4) It is concluded that in the mouse model the ability of buspirone to reduce the aversive response to a brightly illuminated area may reflect an anxiolytic action, that the dorsal raphe nucleus may be an important locus of action, and that the effects of buspirone may reflect an interaction at 5-hydroxytryptamine receptors.
(5) hypoglossal nucleus), whereas in other areas the angiotensinogen gene was expressed only in a certain population of glial cells.
(6) Local application of 8-OH-DPAT (0-5 micrograms) into the median raphe nucleus, facilitated male rat sexual behavior, as evidenced by a decrease in number of intromissions preceding ejaculation and in time to ejaculation.
(7) In addition, lightly immunostained cells were distinguished in the caudal portion of the hypothalamic arcuate nucleus, area of tuber cinereum, retrochiasmatic area, and rostral portion of the paraventricular thalamic nucleus after colchicine treatment.
(8) Arising of the nucleus from a polyheteronomous nucleoid of proeukaryotes.
(9) It is possible that the IgE that linked abnormally with the propofol had specific binding sites for the phenyl nucleus and the isopropyl groups, which are present in propofol and many other drugs.
(10) We conclude that neuronal activities in the region of the retrofacial nucleus are important both in the integration of stimuli from the central chemoreceptors and in defining the discharge patterns of respiratory neurons.
(11) A 68 year-old man with a history of right thalamic hemorrhage demonstrated radiologically in the pulvinar and posterior portion of the dorsomedian nucleus developed a clinical picture of severe physical sequelae associated with major affective, behavioral and psychic disorders.
(12) While the heaviest anterogradely labeled ascending projections were observed to the contralateral ventral posterolateral nucleus of the thalamus, pars oralis (VPLo), efferent projections were also observed to the contralateral ventrolateral thalamic nucleus (VLc) and central lateral (CL) nucleus of the thalamic intralaminar complex, magnocellular (and to a lesser extent parvicellular) red nucleus, nucleus of Darkschewitsch, zona incerta, nucleus of the posterior commissure, lateral intermediate layer and deep layer of the superior colliculus, dorsolateral periaqueductal gray, contralateral nucleus reticularis tegmenti pontis and basilar pontine nuclei (especially dorsal and peduncular), and dorsal (DAO) and medial (MAO) accessory olivary nuclei, ipsilateral lateral (external) cuneate nucleus (LCN) and lateral reticular nucleus (LRN), and to a lesser extent the caudal medial vestibular nucleus (MVN) and caudal nucleus prepositus hypoglossi (NPH), and dorsal medullary raphe.
(13) In contrast to this, adrenalectomy decreased ANP levels markedly in the organum vasculosum laminae terminalis and preoptic periventricular nucleus, which are reportedly involved in the central regulation of salt and water homeostasis.
(14) The shape of the nucleus changes from ovoid to a distinctive, radially splayed lobulated structure.
(15) Immunocytochemical analysis also suggested that bFGF immunoreactivity was present in the nucleus as well as the cytoplasm of astrocytes and CA2 neurons.
(16) The effect of Y-516 on the hyperactivity induced by dopamine injected bilaterally into the nucleus accumbens was compared with those of clocapramine (CCP), haloperidol (HPD) and chlorpromazine (CPZ).
(17) Moderately differentiated tumor revealed a wider range of nucleus size, less clustering (coefficient--3.59) and more hyperchromatic (70.1%) and "bare" (49.4%) nuclei and large nucleoli (22.2%).
(18) The majority of intensively stained and densely packed cells have been observed in tv nucleus.
(19) Following electrical stimulation of the hypothalamic paraventricular nucleus (PVN) area, 21% of the neurons were orthodromically excited, 6% were inhibited and 2.5% were antidromically activated.
(20) Proenkephalin A-related immunoreactive neuronal perikarya were detected in the central gray, reticular formation, nucleus raphes, trapezoid body, nucleus parabrachialis lateralis and medialis, nucleus spinalis nervi trigemini, nucleus dorsalis nervi vagi, and in the nucleus tractus solitarii.