What's the difference between multivalent and site?

Multivalent


Definition:

  • (a.) Having a valence greater than one, as silicon.
  • (a.) Having more than one degree of valence, as sulphur.

Example Sentences:

  • (1) It could be demonstrated that equimolar doses of the bivalent alpha,N-(epsilon,N-DNP-aminocaproyl-)-epsilon,N-DNP-L-lysine and the multivalent dinitrophenylated bovine serum albumin were equally effective in eliciting reactions in skin sites provided that a high affinity antibody was used for sensitization.
  • (2) In meiotic prophase of spermatocytes, chromosomes 2 and 3 form pachytene-diplotene bivalents whose arms may be associated by chiasmata in postdiplotene stages, but the X, Y and fourth chromosomes participate in a complex multivalent.
  • (3) We have used this technique to prepare soluble multivalent heteroligating antibody conjugates that can bind either of two antigenically distinct cell lines, as well as reagents that specifically label murine tumor cells with different MHC class I antigens.
  • (4) This could be due to the multivalency of protein Fel aggregates.
  • (5) Depletion of PKC activity through long term (20 h) exposure of RBL cells to PMA, also inhibited the F-actin response when the cells were stimulated with either multivalent antigen or OAG.
  • (6) We have examined the effects of multivalent cations, principally the polyamine spermine, on the SSB-ss poly(dT) binding mode transitions and find that the transition from the (SSB)35 to the (SSB)56 binding mode can be induced by micromolar concentrations of polyamines as well as the inorganic cation Co(NH3)6(3+).
  • (7) These results suggest that soluble nominal antigen, in an appropriately multivalent form, can bind specifically to antigen receptors on Tc clones.
  • (8) Such hybrid strains have the potential to be used as multivalent vaccines against a number of infectious diseases.
  • (9) The possible role of toxin multivalency and receptor mobility in the mechanism of toxin action is considered.
  • (10) This observation is similar to that made for a variety of small molecular weight materials, such as insulin, digoxin, and morphine, and is in contrast to that for multivalent protein antigens, such as serum albumin and thyroglobulin.
  • (11) No effect of the dwarf condition on the segregation of the translocation multivalent could be noted.
  • (12) Endocytosis of the molecules was induced by addition of multivalent ligands such as rabbit anti-mouse immunoglobulin serum or protein A-bearing liposomes to cells pretreated with anti-H-2Kk antibodies.
  • (13) Therefore, the putative 'hypertensinogenic' receptor may be multivalent with binding sites for F, ALDO and 17 alpha 20 alpha OHP, or is a site of single interactive receptors for these steroids and that F exerts its permissive action by occupying the same site as ALDO on the hypertensinogenic receptors.
  • (14) We propose a unifying explanation for the effects of several accelerating solvents studied here including polymers, di- and multivalent cations, as well as effects seen with the phenol emulsions and single-stranded nucleic acid binding proteins.
  • (15) mLFA-3 binding had characteristics of a multivalent interaction with cell surface CD2 and had an avidity of 1.5 nM for Jurkat cells and 12 nM for resting T cells.
  • (16) Another DNP-biotin hapten that is approximately 10 A longer has four tight binding sites per avidin and, when bound to avidin, has greater activity similar to a highly DNP-conjugated multivalent antigen.
  • (17) Immunization of mice with a combination of passively administered syngeneic IgG (anti-p-azophenylarsonate [anti-Ars]) antibody and a soluble, multivalent form of the antibody's corresponding antigen (Limulus polyphemus hemocyanin conjugated with Ars [Lph-Ars]) resulted in specific autoanti-IgG Fc (rheumatoid factor) production.
  • (18) Sometimes multivalency in the carbohydrate-receptor interaction is crucial.
  • (19) The distribution pattern of the clusters corresponded to that of absorbed and immunogold-labelled poliovirus particles and suggests a multivalent organization of poliovirus binding sites.
  • (20) This association is rapid, and, when triggered by multivalent antigen, it is quickly reversed by the addition of excess monovalent antigen.

Site


Definition:

  • (n.) The place where anything is fixed; situation; local position; as, the site of a city or of a house.
  • (n.) A place fitted or chosen for any certain permanent use or occupation; as, a site for a church.
  • (n.) The posture or position of a thing.

Example Sentences:

  • (1) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
  • (2) "We examined the reachability of social networking sites from our measurement infrastructure within Turkey, and found nothing unusual.
  • (3) The frequency of rare fragile sites was studied among 240 children in special schools for subnormal intelligence (IQ 52-85).
  • (4) The presence of O-glycosidic linkages between carbohydrate and protein in the DF3 antigenic site was further supported by the presence of NaBH4-sensitive sites.
  • (5) The data on mapping the episomal plasmid integration sites in yeast chromosomes I, III, IV, V, VII, XV are presented.
  • (6) A total of 13 ascertainments of folate sensitive autosomal fragile sites is observed, of which 10q23 fragility appears to be the most frequent.
  • (7) A quadripolar catheter was positioned either at the site of earliest ventricular activation during induced monomorphic ventricular tachycardia or at circumscribed areas of the left ventricle.
  • (8) M NET is currently installed in referring physician office sites across the state, with additional physician sites identified and program enhancements under development.
  • (9) The findings suggest that these two syndromes are associated with dysfunction at two different sites within the frontal lobes.
  • (10) An association of cyclophosphamide, fluorouracil and methotrexate already employed with success against solid tumours in other sites was used in the treatment of 62 patients with advanced tumours of the head and neck.
  • (11) In schizophrenic patients the density of dopamine uptake sites in the basal ganglia was slightly reduced, mainly in the middle third of putamen.
  • (12) The findings clearly reveal that only the Sertoli-Sertoli junctional site forms a restrictive barrier.
  • (13) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
  • (14) It was the purpose of the present study to describe the normal pattern of the growth sites of the nasal septum according to age and sex by histological and microradiographical examination of human autopsy material.
  • (15) But earlier this year the Unesco world heritage committee called for the cancellation of all such Virunga oil permits and appealed to two concession holders, Total and Soco International, not to undertake exploration in world heritage sites.
  • (16) The severity and site of hypertrophy is important in determining the clinical picture and the natural history of hypertrophic cardiomyopathy (HCM).
  • (17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
  • (18) In the second approach, attachment sites of DTPA groups were directed away from the active region of the molecule by having fragment E1,2 bound in complex, with its active sites protected during the derivatization.
  • (19) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
  • (20) Scatchard analyses of binding data obtained with synaptosomal preparations from 17-day-old embryos revealed two T3 binding sites.