(v. i. / auxiliary) To be obliged; to be necessitated; -- expressing either physical or moral necessity; as, a man must eat for nourishment; we must submit to the laws.
(v. i. / auxiliary) To be morally required; to be necessary or essential to a certain quality, character, end, or result; as, he must reconsider the matter; he must have been insane.
(n.) The expressed juice of the grape, or other fruit, before fermentation.
(n.) Mustiness.
(v. t. & i.) To make musty; to become musty.
Example Sentences:
(1) Such a signal must be due to a small ferromagnetic crystal formed when the nerve is subjected to pressure, such as that due to mechanical injury.
(2) The catheter must be meticulously fixed to the skin to avoid its movement.
(3) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(4) One must be suspicious of any gingival lesion, particulary if there is a sudden onset of bleeding or hyperplasia.
(5) For assessment of clinical status, investigators must rely on the use of standardized instruments for patient self-reporting of fatigue, mood disturbance, functional status, sleep disorder, global well-being, and pain.
(6) To this figure an additional 250,000 older workers must be added, who are no longer registered as unemployed but nevertheless would be interested in finding another job.
(7) They had learned through hard experience what Frederick Douglass once taught -- that freedom is not given, it must be won, through struggle and discipline, persistence and faith.
(8) Careful attention must be given to antibiotic choice as well as the dose and duration of therapy.
(9) Before carrier vaccines are applied, these risks must be thoroughly evaluated case-by-case.
(10) This suggests that molars do not maintain a fixed relationship to incisors over time, and extreme care must be taken to standardize an experiment to a specific body weight when using this method.
(11) For retrospective action to be taken, and an FA charge to follow, the decision of the panel must be unanimous.” The match between the sides ended in acrimony and two City red cards.
(12) Although esmolol may be used as a primary hypotensive agent, the potential for marked myocardial depression must be recognized.
(13) After the diagnosis of a soft-tissue injury (sprain, strain, or contusion) has been made, treatment must include an initial 24- to 48-hour period of RICE.
(14) Since the plasmid-cured strains did not contain DNA sequences homologous to plasmid DNA, the gene for the free-inclusion protein must be encoded in the chromosome.
(15) If women psychiatrists are to fill some of the positions in Departments of Psychiatry, which will fall vacant over the next decade, much more attention must be paid to eliminating or diminishing the multiple obstacles for women who chose a career in academic psychiatry.
(16) Research must continue to determine the optimal regimen that suppresses testosterone activity with the least amount of toxicity.
(17) Renal arteriography is therefore alone capable of answering two primordial questions: "Must surgery be undertaken and when operating, what surgical tactics to adopt".
(18) Which must make yesterday's jobs figures doubly alarming for the coalition.
(19) It is commonly assumed that the visual resolution limit must be equal to or less than the Nyquist frequency of the cone mosaic.
(20) In assessing damaged nets and curtains it must be recognised that anything less than the best vector control may have no appreciable impact on holoendemic malaria.
Mutt
Definition:
Example Sentences:
(1) The name gastrin releasing peptide (GRP) was given to the porcine and avian heptacosapeptides by McDonald and Mutt.
(2) Such mutants were isolated by using mutT mutagenesis and an enrichment procedure devised to favor the growth of individuals that could form a pellicle in static broth containing alpha-methylmannoside, an inhibitor of erythrocyte binding and pellicle formation.
(3) Previous studies have shown that the mutT, mutH, mutL and mutS mutators of Escherichia coli confer a marked selective advantage on their respective hosts in competition with otherwise isogenic wild-type strains.
(4) 206, 9-16) and indicate that the first of the potential initiation codons (position 164) of the open reading frame in the PvuII fragment carrying the mutT gene is the site of initiation of translation of the 15,000-Da polypeptide.
(5) As Brodie waited to collect a back-pass, the mutt flew at him, knocking the Scotsman to the ground; he was stretchered off, having shattered his kneecap.
(6) Most of the mutants obtained had high spontaneous mutation rates and mapped close to the previously known mutators mutT, mutS, mutR, uvrE and mutL.
(7) The MutT protein, which prevents AT----CG transversions during DNA replication, hydrolyzes nucleoside triphosphates to yield nucleoside monophosphates and pyrophosphate.
(8) Specific labelling of plasmid-encoded proteins by the maxicell method revealed that mutT codes for a polypeptide of about 15,000 daltons.
(9) Obama, at his first press conference after the election, said the family preference was for a dog from a shelter - "a lot of shelter dogs are mutts like me".
(10) Mutt and Jorpes (49) originally isolated cholecystokinin (CCK) from porcine intestine.
(11) This error-avoiding process is catalysed by a protein encoded by the mutT gene of Escherichia coli, mutations of which increase the occurrence of A.T----C.G transversions 100 to 10,000 times the level of the wild type.
(12) These properties of the human 8-oxodGTPase are similar to those observed with the E. coli MutT protein, suggesting that the function of protecting the genetic information from the threat of endogenous oxygen radicals is widely distributed in organisms.
(13) However, the A.G mispairs normally prevented by the mutT function are refractory to mismatch repair, indicating that they may represent a structurally distinct class.
(14) Escherichia coli mutT strains are strong mutators yielding only A.T----C.G transversion mutations.
(15) Except for mutants of mutT type, these mutators also showed high mutability by bromouracil.
(16) A total of 103 ewes from the breeds Black mutt., Texel, Finn.
(17) The mutT nucleoside triphosphatase, which prevents AT----CG transversions during DNA replication, has been crystallized from ammonium sulfate utilizing a novel technique involving vapor diffusion in capillaries.
(18) We present biochemical evidence demonstrating that MutY glycosylase is an important part of a repair system that includes the MutM and MutT proteins.
(19) On the basis of the template specificity of the mutT effect in vitro, we conclude that the mutT effect involves the aberrant processing of A.G rather than T.C mispairs.
(20) We have analyzed the interaction between mutD5 and mutT-induced A:T-->C:G transversions by measuring reversion frequencies in mutD5 and mutT single mutator strains and mutD5mutT double mutator strains using the well-characterized trpA58 and trpA88 alleles.