(n.) Change; alteration, either in form or qualities.
Example Sentences:
(1) Neutrons induced a dose-dependent cytotoxicity and mutation frequency in the AL cells.
(2) The hprt T-cell cloning assay allows the detection of mutations occurring in vivo in the hypoxanthine-guanine phosphoribosyltransferase (hprt) gene of T-lymphocytes.
(3) The pathology resulting from a missense mutation at residue 403 further suggests that a critical function of myosin is disrupted by this mutation.
(4) Mutational mosaicism was used as a developmental model to analyze 1,500 sporadic and 179 familial cases of retinoblastoma from the world literature.
(5) Substances with a leaving group at the C-3 position form unsaturated conjugated cyclic adducts and are mutagenic only in the His D3052 frameshift strains with an intact excision repair system (no urvA mutation).
(6) The results are consistent with our previous suggestion that lethality for virulent SFV infection results from a lethal threshold of damage to neurons in the CNS and that attenuating mutations may reduce neuronal damage below this threshold level.
(7) It is concluded that selection against insertional mutations is unlikely to be the major factor involved in the containment of element abundance.
(8) Combination of domain substitutions to generate the [Glu107,123]bFGF and [Arg19,Lys123,126]bFGF mutants did not show any additivity of the mutations on biological activity.
(9) The plasmid pMucAMucB, constructed from the Haemophilus influenzae vector pDM2, and a similar plasmid, constructed from pBR322, increased the survival after UV irradiation of Escherichia coli AB1157 with the umu-36 mutation and also caused UV-induced mutation in the E. coli strain.
(10) Peptidoglycan synthesis is unaffected by the mutations affecting the core glycosyltransferases.
(11) The v-erb A oncogene of avian erythroblastosis virus is a mutated and virally transduced copy of a host cell gene encoding a thyroid hormone receptor.
(12) Genetical analysis revealed that resistance to trimethoprim resulted from forward mutations at separate loci rather than back mutations of rad 6 or rad 18 alleles.
(13) Studies on asparagine synthetase indicate that resistance to albizziin may be due to altered regulation of asparagine synthetase, structural mutations of the enzyme, and gene amplification.
(14) Mice with mutations in four nonreceptor tyrosine kinase genes, fyn, src, yes, and abl, were used to study the role of these kinases in long-term potentiation (LTP) and in the relation of LTP to spatial learning and memory.
(15) The apparent sensitivity of Escherichia coli K12 to mild heat was increased by recA (def), recB and polA, but not by uvrA, uvrB or recF mutations.
(16) Tumorigenesis is a multistep process involving mutations of dominantly acting proto-oncogenes and mutations and loss-of-function mutations of tumor suppressor genes.
(17) Appropriate mutations in this pre-early gene allowed a productive infection in ColIb+ cells.
(18) Technically speaking, this modality of brief psychotherapy is based on the nonuse of transferential interpretations, on impeding the regression od the patient, on facilitating a cognitice-affective development of his conflicts and thus obtain an internal object mutation which allows the transformation of the "past" into true history, and the "present" into vital perspectives.
(19) Mutant alleles of rutabaga act in the germ line cells to partially suppress the developmental defects caused by dunce mutations.
(20) The extensive conversion of anti-BPDE to B[a]PT-10-sulfonate under conditions where sulfite enhances diolepoxide mutagenicity, when coupled with this enhancement of diolepoxide mutagenicity by B[a]PT-10-sulfonate in the reverse mutation assay, supports this novel B[a]P derivative as a mediator of the sulfite-dependent enhancement of B[a]P genotoxicity.
Transmute
Definition:
(v. t.) To change from one nature, form, or substance, into another; to transform.
Example Sentences:
(1) The decrease was concurrent with transmutation of the tyrosine hydroxylase-like immunopositive (THLI) cells into mature neurons that had abundant elongated neurites with varicosities and synapses on neuronal elements in the host caudate.
(2) The debate is of both a dogmatic and practical nature, dogmatic in that it has bearing on the question of cellular specificity, and practical in that histological transmutation has repercussions on the macroscopic aspect of the tumor, its clinical evolution and even its behaviour vis-a-vis radiation therapy.
(3) The stimulation was assumed to depend on the radiation and transmutation defects in DNA due to H3 disintegration, and to occur when the stream of labelled cells reached the G1r phase.
(4) The abundant data indicate that the shamanistic priest, who was highly placed in the stratified society, guided the souls of the living and dead, provided for the transmutation of souls into other bodies and the personification of plants as possessed by human spirits, as well as performing other shamanistic activities.
(5) These negative results revealed that malignant cells injected 24 hours previously in a mouse (in vivo conditions) differ from a malignant cell suspension in a tube (in vitro conditions) where the lethal effect of 64Cu transmutation was clearly evidenced.
(6) Weaving a historical narrative from slavery through the present, the film and its contributors trace in stark relief, the various transmutations that the oppression of the black body in America has taken, and the ways that criminal justice has been recruited to that end.
(7) The dose to the stem cell nucleus, then, is derived from the number and energy of decays originating in the nuclear mass of 270 X 10(-12) g. The transmutation effect from isotopic decay in DNA is considered in order to arrive at dose equivalents.
(8) In that system pathogenic primacy is given to failures in parental empathy, leading to the technical requirement of providing empathic responses which build a cohesive self through transmuting internalizations.
(9) The transmutation mainly contributes (about 80%) to cell inactivation.
(10) The mutant is 7 times more sensitive than the wild type to transmutation of both isotopes.
(11) Now that central London has been transmuted into a hollowed-out non-dom tax shelter and money laundering facility, Centre Point is now fulfilling its destiny.
(12) Among the various methods for studying the relative effects of transmutation and radiation of incorporated nuclides, simulation of beta radiation by external gamma exposure is of practical importance.
(13) It is shown that the treatment (a) injure specifically via 64Cu transmutation the DNA of the malignant cells and further perform (with thioproline or spermine) a "reverse transformation" on the damage DNA; (b) restore a "noncancer functioning" in the host cells which had become "cancer cells"; this restoration was performed using, at physiological concentrations, natural compounds already present in all cell types such as metal ions, amino acids, vitamin D2, thyroxine and chelating substances.
(14) This correlation suggests that nuclear recoil, electronic excitation, and chemical transmutation are probably of minor importance to the observed biological toxicity with either isotope.
(15) Lethal efficiency of 32P leads to 32P transmutation in DNA amounted to 0.046.
(16) The UV degradation product, which was isolated and identified, showed that irradiation of nimodipine causes oxidation of the dihydropyridine ring and transmutation of the nitro group in the nitrobenzene moiety.
(17) Many of the stories have transmuted into songs and visual artwork, such as the controversial painting Mistake Creek Massacre (depicting the murder of eight Indigenous men, women and children in 1915), by the Kimberley artist Queenie McKenzie.
(18) Radioactive decay in a labelled molecule leads to specific chemical and biological consequences which are due to local transmutation effects such as recoil, electronic excitation, build-up of charge states and change of chemical identity, as well as to internal radiolytic effects.
(19) He accomplished that with the Weavers, the group he formed in 1950, and who would establish a template for the folk revival of that decade and its transmutation in the early 1960s.
(20) The word Bobbitt has transmuted itself into a verb.