(n.) A soft white substance constituting the medullary sheats of nerve fibers, and composed mainly of cholesterin, lecithin, cerebrin, albumin, and some fat.
(n.) One of a group of phosphorized principles occurring in nerve tissue, both in the brain and nerve fibers.
Example Sentences:
(1) Histological studies of nerves 2 years following irradiation demonstrated loss of axons and myelin, with a corresponding increase in endoneurial, perineurial, and epineurial connective tissue.
(2) Cranial MRI revealed delayed myelination in the white matter but no brain malformation.
(3) We have examined the initial events in myelin synthesis, including the insertion and orientation of PLP in the plasma membrane, in rat oligodendrocytes which express PLP and the other myelin-specific proteins when cultured without neurons (Dubois-Dalcq, M., T. Behar, L. Hudson, and R. A. Lazzarini.
(4) Electron microscopic observations of the masseter nerve in the aged cats revealed a disruption of the myelin sheaths and a pronounced increase in collagen fibers in the endoneurium and perineurium.
(5) At 7 days axonal swellings were infrequently observed and the main structural feature was a reduction in myelin thickness in affected nerve fibers.
(6) We measured CSF immunoreactive myelin basic protein (MBP), a marker of acute myelin damage, and sIL-2R levels in the CSF from 11 patients with active relapsing remitting (RR) MS, five with stable RR MS, eight with chronic progressive (CP) MS, five with other neurologic diseases, and three normal controls.
(7) Of 533 myelinated sensory fibers, the size range was 2 micron.
(8) However, when beta-xyloside-treated cultures were supplied with exogenous basement membrane, Schwann cells produced numerous myelin segments.
(9) TCR beta chain gene expression of individual T cell clones that share the same MHC class II restriction and similar fine specificity for the encephalitogenic NH2 terminus of the autoantigen myelin basic protein (MBP) has been examined.
(11) This histochemical difference corresponded to more subtle differences in Nissl and myelin staining patterns, and suggests further structural subdivisions of potential functional significance.
(12) At S-L clefts, paranodal-nodal regions, and Schwann cell nuclei, the axonal areas were smaller and the NF densities were higher than at compact myelinated regions.
(13) We find that the labelled cell has a myelinated axon, but that the axon loses its myelin within 50 microns of the soma and has not yet been traced further.
(14) The apparent Km values for the myelin and the microsomal enzyme were 1.3 X 10(-4) M and 4.3 X 10(-4) M, respectively.
(15) The antigen (a protein doublet of Mr 75,000-80,000) is present in, but not restricted to, the myelin lamellae, since it is distributed along the whole myelinating Schwann cell membrane.
(16) It has been shown previously that oligodendrocytes, which synthesize and maintain myelin in the central nervous system (CNS), are susceptible to attack by homologous complement and that injury may be reversible when lysis is resisted by vesicular removal of membrane attack complexes.
(17) To test whether congenital nemaline myopathy (NM) might have a neurogenic basis, we evaluated the number and frequency distribution of L5 motoneuron cell bodies and their myelinated ventral root (VSR) axons in a typical case.
(18) Pre-treatment of human neutrophils with myelin basic protein selectively inhibits the formyl-peptide-induced chemotaxis, without affecting chemotaxis evoked by casein and activated serum.
(19) A rapid loss of nerve fibres apparently occurred early in the course of compression, since there was a marked decrease in the amount of nerve fibre swelling and Marchi stained degenerating myelin with increasing clinical duration.
(20) The results from gel filtration of glycopeptides indicate that there is a higher content of large molecular weight, sialic acid-rich oligosaccharide units in the glycoprotein of immature myelin.
Myelitis
Definition:
(n.) Inflammation of the spinal marrow or its membranes.
Example Sentences:
(1) Spinal changes in 13 cases included vacuolar myelopathy (7 cases), HIV myelitis (1 case) and ganglio-radiculitis (1 cases), cytomegalovirus myelo-radiculitis (1 case) secondary spread from a lymphoma (1 case) and spinal infarcts due to disseminated intravascular coagulation (1 case).
(2) To our knowledge, this is the second report of myelitis in the course of visceral larva migrans.
(3) A rare case of transverse myelitis caused by schistosomiasis of the spinal cord during pregnancy is presented.
(4) This paper includes a review of the 46 cases of transverse myelitis and SLE published so far with regard to diagnosis, treatment and results, a comparison with the case under study, and the conclusions drawn.
(5) In this study oxcarbazepine was given orally in doses of 300-2700 mg daily to one patient with transverse myelitis and to two patients with multiple sclerosis, all of whom had clinically disabling spasticity in the form of difficulty in walking, lower limb rigidity, spastic contractions of the lower limbs and ankle clonus.
(6) The diagnosis may be overlooked, however, when calcific myelitis is the only manifestation.
(7) The central form is that of diffuse CNS involvement, predominantly with myelitis or cerebellar involvement with or without cranial nerve palsies.
(8) The fact that tranverse myelitis developed late after zoster and was followed by facial nerve palsy is stressed.
(9) We conclude that there is strong association between transverse myelitis in SLE and the presence of aPLA.
(10) baclofen on chronic, dysesthetic, and spasm-related pain (SRP) among patients with spinal spasticity [i.e., multiple sclerosis (MS), spinal cord injury (SCI), transverse myelitis (TMy)].
(11) Human immunodeficiency virus myelitis was evident in 8% of cases.
(12) The benign clinical evolution, under corticosteroid therapy, the negativity of biohumoral examinations of the cerebrospinal fluid and the improvement of the NMR pictures allow the diagnosis of acute spinal myelitis.
(13) In disk space infection with osteomyelitis and in retrospinal abscess, MR images showed characteristic findings, whereas in myelitis, MR images demonstrated nonspecific abnormalities.
(14) Three methods of treatment of acute transverse myelitis are presented.
(15) Brainstem auditory evoked potentials (BAEP) were studied on 38 optic myelitis (OM) and 16 of myelopathy with definite abnormal VEP.
(16) The author describes a 71-year-old woman in whom cutaneous cervical herpes zoster was complicated by the development of cervical myelitis.
(17) The common postirradiation complications are: radiation myelitis, trismus, and otitis media.
(18) Increased CK activity was most frequently associated with a diagnosis of equine protozoal myelitis; CK activity was not increased in 11 horses with cervical compressive myelopathy.
(19) On the contrary, ESR was increased on the suffered body areas in patients with active myelitis.
(20) Human immunodeficiency virus myelitis was associated with HIV encephalitis in 65% of the cases.