(1) The quinolinate synthetase B protein exists in all nadA and nadC mutants examined.
(2) The presence of cAMP + cAMP receptor protein was essential for the complete derepression of nadA while no effect was evident upon nadB.
(3) She alleged that Epstein went on to make her have sex with Nada Marcinkova, another female Epstein associate .
(4) The structure of the adducts is in conformity with the generation and reactions of dehydro NADA quinone methide (or its radical).
(5) Accordingly, desaturase enzyme preparation contained both o-diphenoloxidase activity and NADA quinone:NADA quinone methide isomerase activity.
(6) Resolution of the NADA desaturase system on Benzamidine Sepharose and Sephacryl S-200 columns yielded the above-mentioned quinone isomerase and NADA quinone methide:dehydro NADA isomerase.
(7) The present paper reports on the mechanism by which dehydro-NADA is oxidatively activated to form reactive intermediate(s) as revealed by pulse radiolysis, electron spin resonance spectroscopy, high performance liquid chromatography, and ultraviolet-visible spectroscopic analysis.
(8) Exogenously added NADA quinone was readily converted by these enzyme preparations to N-acetylnorepinephrine and dehydro NADA.
(9) High-copy-number vectors, carrying either gene nadA, nadB or nadA + nadB, increased quinolinate production 1.5-fold, 2.0-fold and 15-fold respectively.
(10) After ecdysis NADA became the major hemolymph catecholamine in all species as DA decreased rapidly.
(11) The NADA desaturase system which converts NADA to 1,2-dehydro-NADA, surprisingly, does not resemble dehydrogenases such as succinate dehydrogenase.
(12) NADA-sulphate was quantified by an HPLC-ECD method while the decrease in 4-MU was monitored continuously by a fluorimetric procedure.
(13) These studies indicate that NADA quinone is an intermediate during the side chain hydroxylation of NADA by Manduca cuticular enzyme(s).
(14) The remaining nicotinamide mononucleotide accumulates extracellularly and will support the growth of nadA pncB mutants which cannot utilize the nicotinamide resulting from the major pathway of NAD degradation.
(15) In addition, the sulfate conjugate formed, namely N-acetyldopamine-sulfate (NADA-sulfate) was quantified directly by high-pressure liquid chromatography cum electrochemical detection (HPLC-ECD).
(16) Kinetic studies with NADA showed two pH optima of 6.7 and 8.6 for the overall sulphate conjugation and the PST reaction while the PAPS generation occurred maximally at pH 8.0.
(17) Reconstitution of NADA side chain desaturase activity was achieved by mixing the last enzyme fraction with NADA quinone isomerase, obtained from the hemolymph of the same organism, and mushroom tyrosinase.
(18) Evidence for the formation of an unstable intermediate in the synthesis of quinolinate from aspartate and dihydroxyacetone phosphate by Escherichia coli was obtained using toluenized cells of nadA and nadB mutants of this organism and partially purified A and B proteins in dialysis and membrane cone experiments.
(19) Media coverage was, not surprisingly, sparse – one interview for Melody Maker is vague to the point of rendering itself totally “nada”, while an Island press release is something of a bad joke.
(20) Confirmation of the operon arrangement for nadA and pnuC was obtained through the sequence analysis of a 2.4-kilobase DNA fragment which complemented both NadA and PnuC mutant phenotypes.
Zero
Definition:
(n.) A cipher; nothing; naught.
(n.) The point from which the graduation of a scale, as of a thermometer, commences.
(n.) Fig.: The lowest point; the point of exhaustion; as, his patience had nearly reached zero.
Example Sentences:
(1) The method is implemented with a digital non-causal (zero-phase shift) filter, based on the convolution with a finite impulse response, to make the computation time compatible with the use of low-cost microcomputers.
(2) Of great influence on the results of measurements are preparation and registration (warm-up-time, amplification, closeness of pressure-system, unhurt catheters), factors relating to equipment and methods (air-bubbles in pressure-system, damping by filters, continuous infusion of the micro-catheter, level of zero-pressure), factors which occur during intravital measurement (pressure-drop along the arteria pulmonalis, influence of normal breathing, great intrapleural pressure changes, pressure damping in the catheter by thrombosis and external disturbances) and last not least positive and negative acceleration forces, which influence the diastolic and systolic pulmonary artery pressure.
(3) The final model has a probability 0.08 of underlying survival time being zero and, given non-zero survival time, takes the form of an exponential distribution with mean of 14.95 months.
(4) Robert Francis QC's official report in February on the Mid Staffordshire care scandal, in which an estimated 400 to 1,200 patients died unnecessarily at Stafford hospital between 2005 and 2008, called for the NHS to make "zero harm" its objective.
(5) Proper maintenance of body orientation was defined to be achieved if the net angular displacement of the head-and-trunk segment was zero during the flight phase of the long jump.
(6) Electromagnetic flow probes with an inner diameter of 2, 1.5 and 1 nm were used for studies on zero-line drifting and for calibration procedures in a series of rats and rabbits.
(7) The open probability is weakly voltage dependent, large at zero and positive potentials (cytoplasm minus SR lumen), and decreasing at negative potentials.
(8) Stepwise depolarizations from the holding potential (-67 to -83 mV) to a potential which varied from -10 to +63 mV resulted in an exponential decline of h from its initial level to a final, non-zero level.
(9) Average increases in nonvellus hair counts between months 4 and 12 were 216, 181, and 264 in the 2% minoxidil, 3% minoxidil, and placebo-to-3% minoxidil crossover groups, respectively, all highly significant differences from zero (p = 0.0001).
(10) For data sampled at a high rate (approximately 200 Hz) pupil velocity deviations from zero can simply be used, giving a satisfactory inaccuracy of about 5 ms. For data sampled at a low rate (less than 50 Hz), e.g.
(11) In 15 patients undergoing aortofemoral bypass, partial thromboplastin time (PTT) tests before and following intravenous administration of 75 U. per kilogram of heparin at zero, 30, 60, 90, and 120 minutes were determined for study of control of anticoagulant adequacy.
(12) As an index of inhomogeneous distribution of inspired air, the mean dilution number (the ratio of the first to zero moments) was calculated from each multibreath nitrogen washout during spontaneous breathing.
(13) Blood pressure was measured with a random-zero sphygmomanometer every 2 weeks of this 8-week trial.
(14) Pairwise correlation between an affected parent and child is zero: The disease is monogenic (no major expression gene).
(15) Where no fluoride was taken zero dmf scores were 41-69 per cent.
(16) He deploys a zero-risk strategy aimed at keeping his rightwing political base behind him, while convincing the public that he alone could lead the country in times of regional turmoil.
(17) Furthermore, the value of the flux ratio for this substance under conditions of zero electrochemical potential across the bowel wall unequivocally demonstrates active transport.
(18) As a result, more and more people are beginning to look towards Irish reunification as being a real possibility.” The overriding issue, however, in this most marginal constituency in Northern Ireland is the old binary, sectarian one: the zero-sum game of orange versus green.
(19) A reduction of tidal volume to zero or an increase by 30% led to a corresponding change of mean carotid artery pH level.
(20) The incidence of probable type B viral hepatitis in patients receiving factor IX concentrate was 13.8 percent (four of 29) versus zero percent (zero of 29) in control patients (difference not significant).