(n.) That point of the heavens, or lower hemisphere, directly opposite the zenith; the inferior pole of the horizon; the point of the celestial sphere directly under the place where we stand.
(n.) The lowest point; the time of greatest depression.
Example Sentences:
(1) Following parturition, NONLAC cows averaged 4.0 d to negative EB nadir and 14.3 d to first ovulation.
(2) Seven days of constant light, however, reverses this diurnal variation such that plasma prolactin levels peak at 11:30 AM and reach a nadir at approximately 11:30 PM.
(3) Microsomal protein synthesis as measured by [3H]leucine incorporation was also depressed in a dose-dependent fashion; however, inhibition did not reach the nadir until day 4, 1 day after renal dysfunction was established.
(4) A trend to a phase-advance of cortisol nadir and melatonin peak was seen in the acutely ill depressed patients with abnormal DST, possibly indicating an involvement of the suprachiasmatic nuclei in the hypothalamus.
(5) The time-related incidence of these cells entities--the appearance of "dusk" and "bright" cells at 5 min, transitory domination of "bright" cells and the nadir of "dusk" cells at 20 min, sporadic recognition of "bright" cells, lack of "dusk" cells at 45 min and the absence of both cell forms at 180 min--displayed that LP-reactive response promptly appeared and rapidly ceased.
(6) In women, but not in men, there was a rise in the risk of falling from 45 years, peaking in the 55-59 year age group, and sinking to a nadir at ages 70-74.
(7) The binding is highest in the early morning and reaches a nadir in the late afternoon.
(8) Strict criteria for dose adjustments according to nadir counts were applied.
(9) One became azoospermic at week 16, while the other's total sperm counts continued declining and reached a nadir of 1.4 million by week 20.
(10) The WBC nadir occurred at a median of 10 days and the median time required for normalization of the WBC was 18 days.
(11) The main toxicity was haematological with delayed leucopenia and thrombopenia (nadir: week 6).
(12) Nadir values coincided with maximal toxic granulation of the neutrophils.
(13) The circadian rhythm observed in patients with intermittent claudication has early evening peaks and a nocturnal trough with a nadir occurring after midnight and before 0400.
(14) Portsmouth , still looking for their first home win under Tony Adams, dominated the first 25 minutes, when Nadir Belhadj was outstanding.
(15) Pre-treatment concentrations of P-FN were within the reference range and significantly higher than the nadir value (p less than 0.05).
(16) A model was constructed according to these two parameters that significantly describes ln (nadir WBC) (p = 0.001).
(17) Following spontaneous horizontal roving eye movement, both eyes deviated downward slowly from midposition, taking 1 to 2 seconds to reach the nadir.
(18) Griffiths replaced Nadir Ciftci for the start of the second half after a dismal first 45 minutes from the home side and Ronny Deila’s men continued to struggle, with Bitton sent off in the 67th minute after picking up his second yellow card.
(19) The second pulse was of slightly lower amplitude, reaching a maximum of 2.3 to 8.0 fold over the control value and 1.25 to 2.5 fold over the preceding nadir.
(20) The period from 2004-5 was the nadir: some American DJs even emigrated to Berlin, where the work prospects were better.
Pessimum
Definition:
Example Sentences:
(1) Variants of mechanism of the response paradoxical weakening at the stimuli increase in conditions of parabiosis and pessimum of the neuro-muscular preparation, are regarded.
(2) The data obtained point out to participation of the synaptic potassium functional feedback (FF) in the phenomena of postactivational potentiation and presynaptic pessimum in the neuromuscular synapse.
(3) A constant temperature gradient is obtained by the irigation in a pessimum position with the head flexed 30 degrees to the front.
(4) The discovery of the intensity of repetitive stimulation pessimum and of the paradoxical response to stregthening of stimuli in a parabiotic nerve, is presented in historical aspect.
(5) With further increase of current strength to 0.9-1.1 mA the stress-induced rise in corticosteroids reduces and Wedensky pessimum is observed.
(6) There exist optimum and pessimum for learning PRCR values at different regimes of reinforcement.