(1) Dysplastic naevus syndrome (DNS) is frequently observed in association with familial melanoma and xeroderma pigmentosum (XP), but the role of UV-light in the development of DNS has not been elucidated.
(2) This feature can be found in several dermatoses and particularly in lichen striatus and acantholytic linear naevus.
(3) Mean naevus numbers were greater in young than in older adults, and in females than in males.
(4) The mean total body naevus count was 115 in the cases and 67 in the controls.
(5) Analysing the cases according to Clark's levels and Breslow's index, a decrease in the naevus-melanoma association was seen with tumour progression, suggesting that advanced tumours may overgrow pre-existing nevus cells, appearing as de novo melanomas.
(6) A bone scan and red blood cell scan in the rare epidermal naevus syndrome, associated with multiple haemangiomas of the bone and hypophosphataemic osteomalacia in a 20-year-old man are reported.
(7) The activities of 27 enzymes of carbohydrate metabolism and the proportions of lactate dehydrogenase isoenzymes were determined in epidermis, in superficial epitheliomas and in several solid tumours biopsied from a patient with basal-cell naevus syndrome.
(8) One of the causes of twenty nail dystrophy of childhood may be a localized tissue malformation, analogous to inflammatory linear verrucous epidermal naevus.
(9) This is particularly true for skin lesions related to the vascular system (e.g., livedo racemosa, spider naevus).
(10) Two hundred moles were examined histologically and the degree and type of epidermal change was recorded and correlated with the arrangement, density and type of naevus cells present and with the clinical presentation.
(11) The clinical, histological and histogenetic aspects of naevus follicularis keratosus (NFK) ("naevus comedonicus") are reported.
(12) Doubt is cast also upon the validity of the concepts of a dysplastic naevus and a dysplastic naevus syndrome.
(13) Secondly, a study in Canadian school children revealed significantly higher naevus counts in subjects with numerous or severe episodes of sunburn in the previous 5 years.
(14) There is some doubt as to whether naevus pilus is identical with naevus-on-naevus or lentiginous naevus en mottes.
(15) An immunohistological evaluation of the diagnosis of naevus-associated melanoma was also performed on the basis of specimens from 89 melanocytic lesions.
(16) The case of a 5-month-old black female child with a linear sebaceous naevus syndrome and multiple congenital anomalies is presented.
(17) We report on the clinical and pathological features of three patients (two girls and one boy aged 6, 12 and 11 years respectively) from the St Laurentius hospital (Roermond, Netherlands) with melanoma of the skin, in whom the lesions histologically resembled the more frequently occurring spindle and epithelioid cell naevus (SE naevus).
(18) The authors report a case of extensive verrucous epidermal naevus of the face in a 15 year old Senegalese boy.
(19) The patient had extensive cutaneous naevus involving the left side of the body and consisting of naevus flammeus, hemangioma cavernosum, and naevus verrucosus.
(20) The difference in naevus count between the exposed and the protected area was larger in patients than in controls, p less than 0.001.
Nevus
Definition:
Example Sentences:
(1) Furthermore, it involved mixed clinical and histological changes of epidermal nevus from fingers to elbow.
(3) A giant congenital pigmented nevus combining an epidermal and a blue nevus is described in a boy.
(4) In view of the difficulties encountered in clinical differential diagnosis, above all with reference to malignant melanoma, nevus lesions should be removed from the oral mucosa.
(5) The increase of the relative risk was 16 x for persons with greater than 60 MCN compared to individuals with greater than or equal to 10 MCN and there was an additional 7 x increase of the relative risk for persons with greater than or equal to 1 dysplastic nevus.
(6) Binding of monoclonal antibodies secreted by hybridomas generated by immunization of mice with VGP primary and metastatic melanoma was highest with cells and supernatants of cultures from advanced melanoma and least with nevus cells.
(7) The clinical and histopathological picture of a 27-year-old patient with generalized nevus verrucosus is described.
(8) Kamino's eosinophilic globules could be considered another important sign for the differential diagnosis between pigmented spindle cell nevus and malignant melanoma.
(9) An extensive congenital melanocytic nevus is described which, in its deeper portion, had striking neurofibromatous features.
(10) The growth of nevus cells is probably comparable to that induced in other cells by traumatic injury.
(11) Spherical nevus cells however are completely devoid of dendritic processes.
(12) The association between melanoma and giant congenital nevocellular nevus has been well documented, although controversy still exists regarding the precise incidence.
(13) Dermal fibroblasts from patients with the autosomal dominant cancer-prone disease Basal Cell Nevus Syndrome (BCNS) exhibit a serum dependence, anchorage dependence and in vitro lifespan (about 20 population doublings or less) similar to those of fibroblasts from normal age-, race- and sex-matched controls.
(14) Some of the them have made in possible to localize the gene of the familial cutaneous melanoma with pleomorphic nevus on 1p chromosome.
(15) Two lesions occurred in examples of nevus sebaceus of Jaddasohn.
(16) Our study shows that HMB-45 also reacts with cells of the blue nevus, a unique type of intradermal nevus.
(17) In contrast to the broad reactivity with melanomas, isolated nevus nests were stained in only 1 of 55 nevi investigated.
(18) We report on a nevus of the oral mucosa, which became present in the age of 30 of a male patient.
(19) Melanoma most often develops in the skin; usually at the site of a preexisting nevus.
(20) To our knowledge, this represents the second reported case of marked folding of the skin; with an underlying nevus lipomatosus; this case demonstrated an association of this cutaneous disorder with multiple defects, including chromosomal abnormalities, which have not been previously reported.