(1) Maternal alloimmunization against fetal platelets can cause fetal and neonatal thrombocytopenia (NAIT).
(2) Improvements in antenatal diagnosis and in utero therapy facilitate appropriate management of pregnancy at risk for NAIT.
(3) There is evidence that in certain cases antibodies against blood group antigens A or B may cause NAIT.
(4) Recent evidence that NAIT is more common than has previously been recognised, a better understanding of the molecular basis of platelet serology and advances in technology, which have made it possible to take blood samples from fetuses and transfuse them in utero, have all contributed to a growing interest in this condition.
(5) Neonatal alloimmune thrombocytopenia (NAIT) is caused by platelet antigen incompatibility between the mother and fetus.
(6) Neonatal alloimmune thrombocytopenia (NAIT) occurs when maternal alloantibodies to antigens present on fetal platelets cause their immune destruction resulting in thrombocytopenia in the newborn infant or fetus.
(7) Neonatal alloimmune thrombocytopenia (NAIT) is due to fetomaternal incompatibility for platelet specific antigens, most frequently HPA-1a (PLA1) and HPA-5b (BRa).
(8) A 31 year old woman was assessed following delivery of her second child affected by neonatal alloimmune thrombocytopenia (NAIT).
(9) An immune response to human platelet antigens (HPA), as in neonatal alloimmune thrombocytopenia (NAIT) and post-transfusion purpura (PTP), is the exception rather than the rule and evidence is accumulating for the importance of human leucocyte antigen (HLA) class II restriction in this situation.
(10) This report of an unaffected pregnancy in a woman with a history of previous pregnancies complicated by NAIT illustrates the role of paternal and fetal platelet phenotyping in managing existing pregnancies at risk of NAIT.
(11) The sera of 219 Zwa-positive mothers who gave birth to children with clinically suspected neonatal alloimmune thrombocytopenia (NAIT) were tested for platelet-reactive antibodies using the platelet adhesion immunofluorescence test and a glycoprotein-specific immunoassay (MAIPA).
(12) Because there is high risk that subsequent pregnancies might be also affected by NAIT, the mothers of a previously affected child should be managed similarly to the HPA-1b mothers (PIA2, Zwb).
(13) Platelet specific alloantibodies cause neonatal alloimmune thrombocytopenia (NAIT), posttransfusion purpura (PTP) and may be found in patients who are refractory to HLA-matched platelet transfusion.
(14) In accordance with established criteria, the Sra antigen represents the first example of a "private" platelet alloantigen that bears significance in rare instances of NAIT.
(15) We report our experience with the serological diagnosis of 14 NAIT cases using new performing techniques such as western blotting (WB) and MAIPA (monoclonal antibody specific immobilization of platelet antigens).
(16) This is a report of 39 cases of NAIT involving the HPA-5b antigen.
(17) Bra antibodies were from mothers of children with neonatal alloimmune thrombocytopenia (NAIT), and anti-Brb was found in the serum of a polytransfused patient.
(18) NAIT is mainly due to alloimmunization; the frequency varying among ethnic groups.
(19) Immunization against these alloantigens is implicated in NAIT and poly-transfused patients.
(20) In the serum of a mother who gave birth to a child with the typical clinical picture of NAIT we found an antibody directed against the new platelet antigen Sra.
Wait
Definition:
(v. i.) To watch; to observe; to take notice.
(v. i.) To stay or rest in expectation; to stop or remain stationary till the arrival of some person or event; to rest in patience; to stay; not to depart.
(v. t.) To stay for; to rest or remain stationary in expectation of; to await; as, to wait orders.
(v. t.) To attend as a consequence; to follow upon; to accompany; to await.
(v. t.) To attend on; to accompany; especially, to attend with ceremony or respect.
(v. t.) To cause to wait; to defer; to postpone; -- said of a meal; as, to wait dinner.
(v. i.) The act of waiting; a delay; a halt.
(v. i.) Ambush.
(v. i.) One who watches; a watchman.
(v. i.) Hautboys, or oboes, played by town musicians; not used in the singular.
(v. i.) Musicians who sing or play at night or in the early morning, especially at Christmas time; serenaders; musical watchmen.
Example Sentences:
(1) I can't wait to see what Christie and her patriarchy-smashing pals do next.
(2) Mike Ashley told Lee Charnley that maybe he could talk with me last week but I said: ‘Listen, we cannot say too much so I think it’s better if we wait.’ The message Mike Ashley is sending is quite positive, but it was better to talk after we play Tottenham.” Benítez will ask Ashley for written assurances over his transfer budget, control of transfers and other spheres of club autonomy, but can also reassure the owner that the prospect of managing in the second tier holds few fears for him.
(3) I said: ‘Apologies for doing this publicly, but I did try to get a meeting with you, and I couldn’t even get a reply.’ And then I had a massive go at him – about everything really, from poverty to uni fees to NHS waiting times.” She giggles again.
(4) It is possible that the high level of radiolabeled phospholipid found in the plasma membrane arose via the de novo pathway following the cleavage of an acyl group as we have found cytidine diphosphocholine phosphotransferase in the plasma membrane fraction (Wang, P., DeChatelet, L.R., and Waite, M. (1977) Biochim.
(5) Meanwhile Ed Miliband, the Labour leader, waiting anxiously for news of the scale of the Labour advance in his first nationwide electoral test, will urge the electorate not to be duped by the promise of a coalition mark 2, predicting sham concessions by the Conservatives .
(6) There are currently more than 380,000 households on local authority waiting lists in the capital – and the number is growing every day.
(7) If we’re waiting around for the Democratic version to sail through here, or the Republican version to sail through here, all those victims who are waiting for us to do something will wait for days, months, years, forever and we won’t get anything done.” Senator Bill Nelson, whose home state of Florida is still reeling from the Orlando shooting, said he felt morally obligated to return to his constituents with results.
(8) Terry Waite Chair, Benedict Birnberg Deputy chair, Antonio Ferrara CEO The Prisons Video Trust • If I want to build a bridge, I call in a firm of civil engineers who specialise in bridge-building.
(9) As a member of the state Assembly, Walker voted for a bill known as the Woman’s Right to Know Act, which required physicians to provide women with full information prior to an abortion and established a 24-hour waiting period in the hope that some women might change their mind about undergoing the procedure.
(10) Strict precautions are necessary to prevent the catastrophic events resulting from inadvertent gentamicin injection; such precautions should include precise labeling of all injectable solutions on the surgical field, waiting to draw up injectable antibiotics until the time they are needed, and drawing up injectable antibiotics under direct physician observation.
(11) If there’s a fire in the house, you don’t sit there saying we’re going to wait until the fire commissioner comes,” she said.
(12) Joe Gregory, parked outside the arena while waiting to pick up his girlfriend and her sister from the concert, captured its impact on his car’s dashcam.
(13) According to Nigerian government figures, there were more than 7,000 spills between 1970 and 2000, and there are 2,000 official major spillage sites, many going back decades, with thousands of smaller spills still waiting to be cleared up.
(14) At posttreatment, subjects in both active treatments reported significant improvement on self-report and interview measures of depression while subjects in the waiting list condition reported minimal change.
(15) Shenhua Watermark Coal, a subsidiary of the Chinese state-owned Shenhua Group, is waiting for final approval from Hunt for a $1.2bn open-cut coalmine on the edge of the plains, a little more than three kilometres from Hamparsum’s property.
(16) Separate calculation of changes in prolactin after the course of medical treatment, pregnancies or 'just waiting' periods showed mean PRL concentrations to be significantly lower only for 'functional' patients after pregnancy.
(17) It's also worth noting that if the Help to Buy scheme really does inflate house prices, by waiting five years before you buy you run the risk of not actually being able to save enough for a 10% deposit, because you'll need a bigger amount than you now need.
(18) Would I be stupid not to wait another six months or so, to get a 90% mortgage given the cons of Help to Buy?
(19) A group placed on a waiting list for 3 weeks was used as a control group.
(20) "I don't think that people are waiting for the wrong solution."