(a.) Having the properties of a narcotic; operating as a narcotic.
(n.) A drug which, in medicinal doses, generally allays morbid susceptibility, relieves pain, and produces sleep; but which, in poisonous doses, produces stupor, coma, or convulsions, and, when given in sufficient quantity, causes death. The best examples are opium (with morphine), belladonna (with atropine), and conium.
Example Sentences:
(1) The clinical usefulness of neonatal narcotic abstinence scales is reviewed, with special reference to their application in treatment.
(2) Recent research conducted by independent investigators concerning the relationship between crime and narcotic (primarily heroin) addiction has revealed a remarkable degree of consistency of findings across studies.
(3) The interactions of 3 classical alpha-adrenergic antihypertensives of prevalently central type (St 155 or clonidine St 600; BR 750 or guanabenz) with the narcotic effects of pentobarbital have been investigated in the Mus musculus.
(4) We studied the arterial blood gas determinations done on the first hospital day in 14 narcotic addicts with bacterial endocarditis (group 1) and six addicts with other medical complications of narcotic addiction (group 2).
(5) The prostaglandins A1, E1, A2, E2 and F2a were comparatively studied for their antiarrhythmic action using the model of strophanthin arrhythmia of narcotized cats.
(6) Postoperative nausea and vomiting have been associated with the use of intravenous narcotics, and nitrous oxide may worsen the emetic effects of narcotics.
(7) Though intraspinal narcotic analgesia is associated with a number of side effects, with proper knowledge these adverse reactions are wither preventable or can be greatly reduced.
(8) In this open study we reviewed the circadian distribution of extra doses of narcotic analgesics in 61 bed-ridden patients with cancer pain.
(9) In narcotized cats different respiratory reactions in acute myocardial ischemia was estimated with complicated and non-complicated ventricular fibrillation.
(10) Infants prenatally exposed to narcotics become passively addicted in-utero and may undergo neonatal abstinence at birth.
(11) Convergent results from a multimethod assessment of the issue show that methadone maintenance has long-term and short-term suppressive effects on narcotics use and property crime.
(12) The pharmacokinetics of the narcotic analgesic dextromoramide was investigated by means of a specific GC-MS method in 9 patients who were given a single oral dose of the drug (7.5 mg) together with an anticholinergic before undergoing minor orthopedic surgery.
(13) Ethanol-withdrawn animals displayed an increased sensitivity to the narcotic action of toluene.
(14) Their addiction at the time of seeking treatment was well established: narcotic drugs comprised their main daily expenditure, they had numerous problems associated with narcotic use, and high doses of methadone were necessary for detoxification.
(15) These results provide further evidence that narcotic-induced respiratory depression and analgesia are mediated by different receptor interactions.
(16) Hypericum extract enhanced the exploratory activity of mice in a foreign environment, significantly prolonged the narcotic sleeping time dose-dependently, and within a narrow dose range exhibited reserpine antagonism.
(17) In summary, there are now available very potent narcotics, with small side effect liability.
(18) This paper analyses the influence of medical professional organization on the formation of attitudes and policies toward narcotics in England.
(19) Most involved children less than 3 (42%) yr or greater than 12 (33%) yr. Products most commonly ingested included tricyclic antidepressants (22%), benzodiazepines (15%), theophylline (10%), ethanol (10%), hallucinogens (8%), salicylates (8%), narcotics (8%), antihistamines (7%), and carbamazepine (5%).
(20) In this respect the narcotic antagonist effects resemble those produced by the antiserotonin compounds or opiate agonists.
Reduce
Definition:
(n.) To bring or lead back to any former place or condition.
(n.) To bring to any inferior state, with respect to rank, size, quantity, quality, value, etc.; to diminish; to lower; to degrade; to impair; as, to reduce a sergeant to the ranks; to reduce a drawing; to reduce expenses; to reduce the intensity of heat.
(n.) To bring to terms; to humble; to conquer; to subdue; to capture; as, to reduce a province or a fort.
(n.) To bring to a certain state or condition by grinding, pounding, kneading, rubbing, etc.; as, to reduce a substance to powder, or to a pasty mass; to reduce fruit, wood, or paper rags, to pulp.
(n.) To bring into a certain order, arrangement, classification, etc.; to bring under rules or within certain limits of descriptions and terms adapted to use in computation; as, to reduce animals or vegetables to a class or classes; to reduce a series of observations in astronomy; to reduce language to rules.
(n.) To change, as numbers, from one denomination into another without altering their value, or from one denomination into others of the same value; as, to reduce pounds, shillings, and pence to pence, or to reduce pence to pounds; to reduce days and hours to minutes, or minutes to days and hours.
(n.) To change the form of a quantity or expression without altering its value; as, to reduce fractions to their lowest terms, to a common denominator, etc.
(n.) To bring to the metallic state by separating from impurities; hence, in general, to remove oxygen from; to deoxidize; to combine with, or to subject to the action of, hydrogen; as, ferric iron is reduced to ferrous iron; or metals are reduced from their ores; -- opposed to oxidize.
(n.) To restore to its proper place or condition, as a displaced organ or part; as, to reduce a dislocation, a fracture, or a hernia.
Example Sentences:
(1) There was appreciable variation in toothbrush wear among subjects, some reducing their brush to a poor state in 2 weeks whereas with others the brush was rated as "good" after 10 weeks.
(2) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(3) These included bringing in the A* grade, reducing the number of modules from six to four, and a greater attempt to assess the whole course at the end.
(4) It is concluded that amlodipine reduces myocardial ischemic injury by mechanism(s) that may involve a reduction in myocardial oxygen demand as well as by positively influencing transmembrane Ca2+ fluxes during ischemia and reperfusion.
(5) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(6) With aging, the blood vessel wall becomes hyperreactive--presumably because of an augmented vasoconstrictor and a reduced vasodilator responsiveness.
(7) In addition, DDT blocked succinate dehydrogenase and the cytochrome b-c span of the electron transport chain, which also secondarily reduced ATP synthesis.
(8) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(9) At pH 7.0, reduction is complete after 6 to 10 h. These results together with an earlier study concerning the positions of the two most readily reduced bonds (Cornell J.S., and Pierce, J.G.
(10) Methanosphaera stadtmanae reduces methanol to CH4 in a similar way as Methanosarcina barkeri.
(11) There is no evidence that health-maintenance organizations reduce admissions in discretionary or "unnecessary" categories; instead, the data suggest lower admission rates across the board.
(12) In schizophrenic patients the density of dopamine uptake sites in the basal ganglia was slightly reduced, mainly in the middle third of putamen.
(13) During recovery glucose uptake was reduced and citrate release was unaffected.
(14) The difference in BP between a hospital casual reading and the mean 24 hour ambulatory reading was reduced only by atenolol.
(15) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(16) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(17) aeruginosa and Enterococci) were significantly reduced in number during the manipulation (Fig.
(18) Arginine vasopressin further reduced papillary flow in kidneys perfused with high viscosity artificial plasma.
(19) Epidermal growth factor reduced plating efficiency by about 50% for A431 cells in different cell cycle phases whereas a slight increase in plating efficiency was seen for SiHa cells.
(20) Nicardipine lowered systolic and diastolic blood pressure to normal, plasma aldosterone was reduced and serum potassium levels were increased.