(n.) The death of a part by molecular disintegration and without loss of continuity, as in the processes of degeneration and atrophy.
Example Sentences:
(1) Towards the end of the observation period erosions of cartilage, pannus formation and periarticular foci of purulent necrobiosis were found.
(2) The identity between necrobiosis lipoidica with other chronic granulomatous diseases and the possible treatment of this benign but long-term process is briefly discussed.
(3) RN tended to show homogeneous, eosinophilic necrobiosis, giant cells within palisaded foci, and significant stromal fibrosis; while lesions of SGA showed pale, edematous necrobiosis, an absence of giant cells, and lesser degrees of fibrosis.
(4) In one out of the three dogs with combined operation, scattered foci of necrobiotic sinus node cells and necrobiosis of the medial smooth muscle cells in sinus node arteries were also observed.
(5) These findings support a vascular origin of necrobiosis lipoidica, involving reduced vascular perfusion combined with diffusion block.
(6) However, it has not been associated previously with necrobiosis lipoidica diabeticorum (NBL), a rare skin manifestation of diabetes mellitus.
(7) Statistically significant hypoxia was found in the area of necrobiosis lipoidica, which was even more pronounced in the inflamed border.
(8) Cortisone-herapin and cortisone-maltose tetrapalmitate (MTP) treatments induced focal areas of tumor necrosis and necrobiosis, whereas cortisone alone caused necrobiosis.
(9) A diabetic patient is described presenting psoriasis, necrobiosis lipoidica diabeticorum, granuloma annulare, and vitiligo and with a history of recurrent erysipelas and mycotic infections.
(10) In patients with portal cirrhosis, sclerotic changes rather than necrobiosis was observed in the pancreas.
(11) A case of necrobiosis lipoidica diabeticorum (NLD) in a 12-year-old male patient is described.
(12) Finally, in six elliptical biopsies extending into clinically normal skin, we demonstrated that the inflammatory infiltrate of necrobiosis lipoidica diabeticorum extended from the lesion into apparently normal skin surrounding clinically active lesions.
(13) Our report describes a 52-year-old female patient with bilateral foci of necrobiosis lipoidica in pretibial scars.
(14) Results of an open trial of platelet inhibitor treatment for necrobiosis lipoidica diabeticorum suggest the possible importance of abnormal platelet function in this disease.
(15) Common features included extensive hyaline necrobiosis and foreign-body giant cells.
(16) We confirmed that cutaneous anesthesia is usually present in the necrobiosis lipoidica diabeticorum lesions.
(17) Liver function test showed signs of moderate necrobiosis with impaired biliary acid metabolism.
(18) The associations between the granulomatous disorders of the skin, especially necrobiosis lipoidica, sarcoidosis and granuloma annulare, are discussed.
(19) A statistically significantly higher number of these cells was found within the epidermis in necrobiosis lipoidica compared with granuloma annulare and normal skin.
(20) Tissue hypoxia and an infection, arising against this background, lead to the expansion of necrobiosis and to the occurrence of trophic ulcers.
Tissue
Definition:
(n.) A woven fabric.
(n.) A fine transparent silk stuff, used for veils, etc.; specifically, cloth interwoven with gold or silver threads, or embossed with figures.
(n.) One of the elementary materials or fibres, having a uniform structure and a specialized function, of which ordinary animals and plants are composed; a texture; as, epithelial tissue; connective tissue.
(n.) Fig.: Web; texture; complicated fabrication; connected series; as, a tissue of forgeries, or of falsehood.
(v. t.) To form tissue of; to interweave.
Example Sentences:
(1) In conclusion, the efficacy of free tissue transfer in the treatment of osteomyelitis is geared mainly at enabling the surgeon to perform a wide radical debridement of infected and nonviable soft tissue and bone.
(2) If ascorbic acid was omitted from the culture medium, the extensive new connective tissue matrix was not produced.
(3) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
(4) The Cavitron Ultrasonic Surgical Aspirator (CUSA) is a dissecting system that removes tissue by vibration, irrigation and suction; fluid and particulate matter from tumors are aspirated and subsquently deposited in a canister.
(5) Bilateral symmetric soft-tissue masses posterior to the glandular tissue with accompanying calcifications should suggest the diagnosis.
(6) In cardiac tissue the adenylate system is not a good indicator of the energy state of the mitochondrion, even when the concentrations of AMP and free cytosolic ADP are calculated from the adenylate kinase and creatine kinase equilibria.
(7) Spectrophotometric determination of the sulfhydryl content in the animal tissue before (control) and after using 6,6'-Dithiodinicotinic acid is applied.
(8) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(9) The vascular endothelium is capable of regulating tissue perfusion by the release of endothelium-derived relaxing factor to modulate vasomotor tone of the resistance vasculature.
(10) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
(11) The human placental villus tissue contains opioid receptors and peptides.
(12) Some of those drugs are able to stimulate the macrophages, even in an aspecific way, via the gut associated lymphatic tissue (GALT), that is in connection with the bronchial associated lymphatic tissue (BALT).
(13) The diffusion of Myocamicin in the prostatic tissue of patients undergoing prostatectomy after a single oral dose of 600 mg has been studied.
(14) Blood flow decreased immediately after skin expansion in areas over the tissue expander on days 0 and 1 and returned to baseline levels within 24 hours.
(15) However, decapitation did not eliminate the sex difference in the tissue content of P4 during control incubations.
(16) Content of cyclic nucleoside monophosphates was decreased in all the eye tissues in experimental toxico-allergic uveitis as well as penetration of cAMP into the fluid of anterior chamber of the eye.
(17) Histological studies of nerves 2 years following irradiation demonstrated loss of axons and myelin, with a corresponding increase in endoneurial, perineurial, and epineurial connective tissue.
(18) None of the other soft tissue layers-ameloblasts, stratum intermedium or dental follicle--immunostain for TGF-beta 1.
(19) One of these antibodies, MCaE11, was used for immunohistochemical detection of MAC in tissue and for quantification of the fluid-phase TCC in ethylenediaminetetraacetic acid plasma.
(20) A quantitative comparison of tissue distribution and excretion of an orally administered sublethal dose of [3H]diacetoxyscirpenol (anguidine) was made in rats and mice 90 min, 24 hr, and 7 days after treatment.