(1) In contrast to the intact endothelial monolayers, in homogenates additional kininase activity was found which was not affected by either ACE and NEP inhibitors nor by amastatin and MGTA.
(2) These data indicate that mammalian tachykinins induce the release of NCA from BBEC and that NEP modulates these effects.
(3) The nuclear masses are known as (1) the area lateralis hypothalami (ALH), (2) the nucleus entopeduncularis (nEp), (3) the nucleus semilunaris accessorius (nSA), (4) the nucleus ventromedialis hypothalami (nVmH), and (5) the posterolateral portion of the zona incerta (ZI).
(4) The effects of the neutral metalloendopeptidase (NEP) inhibitor, thiorphan, and the angiotensin converting enzyme (ACE) inhibitor, captopril, on airway responses to SP5-11 were examined in order to test the hypothesis that differences in degradation of SP and SP5-11 contribute to the difference in airway responsiveness to the two peptides.
(5) These results suggest that degradation of NKA and NKB by NEP but not by ACE is an important determinant of the bronchoconstriction induced by these peptides.
(6) By cleaving and thus inactivating tachykinins released from sensory nerves, NEP limits the actions of these peptides.
(7) We gave phosphoramidon to inhibit NEP and enalapril maleate or captopril to inhibit ACE.
(8) The effects of neutral endopeptidase inhibition (NEP-I) were studied in 6 conscious sheep with heart failure (HF) induced by rapid ventricular pacing for 7 days.
(9) The present work examined the susceptibility of these novel peptides to hydrolysis by various purified exo- and endo-peptidases including endopeptidases 24.11 (NEP), 24.15, 24.16, angiotensin-converting enzyme, leucine aminopeptidase and carboxypeptidase A. NEP attacked MCH at three sites of the molecule with an apparent affinity of about 12 microM and a kcat.
(10) On the other hand, transient or enhanced expression of NEP is observed during the development of several organs such as the sensory organs, the heart and the major blood vessels, the intestine, the bones and the genital tubercle.
(11) These studies confirm the presence of neutral endopeptidase (NEP) in the nuchal ligament of the fetal calf.
(12) Regional haemodynamic responses to atrial natriuretic peptide (ANP, 0.5 nmol kg-1) or proendothelin-1 [1-38] (1.0 nmol kg-1) were assessed in the same conscious Long Evans rats before and 20 min after administration of the novel neutral endopeptidase (NEP) inhibitor, SQ 28,603 (50 mg kg-1, i.v.).
(13) The activity of NEP, measured with an enzymatic fluorimetric method employing N-dansyl-D-alanyl-glycyl-L-4-nitrophenylalanyl-glycine as a synthetic substrate, was 18 times and eight times higher in the outer stripe of the medulla and inner cortex than in the outer cortex (OC).
(14) There were no significant differences in apparent volume of distribution, elimination half-life, and elimination clearance (CIe) for nEp and rEp in intact dogs.
(15) Also examined were the effects of inhibitors of neutral endopeptidase (NEP) and angiotensin-converting enzyme (ACE).
(16) This binding was displaced in a dose-dependent manner by NEP inhibitors.
(17) Using NEP-expressing MDCK cells and episcopic fluorescence microscopy, a specific labeling was obtained with 100 nM FTI which was completely displaced by 10 microM HACBOGly, a specific and potent inhibitor of NEP.
(18) We concluded that, although covalent bonds appear to be cleaved in NEP by papain, its activity and structure are sustained by S-S bridges.
(19) To determine the distribution of NEP, a possible regulatory enzyme for the neuropeptide-induced leukocyte activation, among human leukocytes, we investigated the enzymatic activity of NEP in each cell type of human peripheral blood leukocytes.
(20) N-ethyl piperidinyl diaminodithiol (NEP-DADT), complexed with 99mTc has been developed as an agent for the measurement of brain blood flow using SPECT.
Ney
Definition:
(n.) A fabric of twine, thread, or the like, wrought or woven into meshes, and used for catching fish, birds, butterflies, etc.
(n.) Anything designed or fitted to entrap or catch; a snare; any device for catching and holding.
(n.) Anything wrought or woven in meshes; as, a net for the hair; a mosquito net; a tennis net.
(n.) A figure made up of a large number of straight lines or curves, which are connected at certain points and related to each other by some specified law.
Example Sentences:
(1) Temperature adjustment of INFRARED (NEY Co.) is to use Powerlevel, and of BEAMWERDER (YOSHIDA Co.) is adjusting the height of the turn table.
(2) The results indicated that gold alloys responded slightly better than Ney 76 alloy, but similar to Albacast alloy with adequate correlation between the four criteria evaluated.
(3) The proposed clasp corresponds to two Ney type I clasps acting on one tooth.
(4) For those not familiar with the Big-Phil-Little-Ney dynamic in the flesh, Brazil’s first press conference on the eve of the tournament was intriguing, so gurglingly affectionate are the pair of them in public.
(5) (2) The Ney G-3 as-welded samples had no ductility, but heat treating greatly increased their yield stress.
(6) As well as announcing the funding, Eric Pickles , the communities secretary, on Thursday said the commissioners who would take over the running of crisis-hit Rotherham council were Sir Derek Myers, Stella Manzie, Malcolm Newsam, Mary Ney and Julie Kenny.
(7) The lead Labour member on the Metropolitan Police Authority, Joanne McCart ney, tonight wrote to the Metropolitan police commissioner, Sir Paul Stephenson, asking for details of senior officers whose voicemail may have been intercepted by Mulcaire.
(8) The authors remind the original principles having led Akers, Roach and Ney in the conception of their "retentive complexes" and analyse the main biomechanical concepts included in their propositions.
(9) As a congressional aide in the late 1990s to former Ohio congressman Bob Ney, he brought an unloaded gun into a House of Representatives building on Capitol Hill.
(10) The alloy Ney Cast III is superior in performance to the other low golds and approximately equivalent to the high-gold alloy Firmilay.
(11) The authors describe the different "retentive complexes" proposed by the Akers, Roach and Ney schools and analyse their biomechanical validity.
(12) Speaker Ryan is giving a green light to congressional corruption.” The OCE was created in March 2008 after the cases of former Representative Randy “Duke” Cunningham, a Republican from California, who served more than seven years in prison on bribery and other charges; as well as cases involving former Representative Bob Ney, a Republican from Ohio, who was charged in the Jack Abramoff lobbying scandal and pleaded guilty to corruption charges, and former Representative William Jefferson, a Democrat from Louisiana, convicted on corruption in a separate case.
(13) In curating the collective, co-producers Miles Jay and Mina Girgis sought to highlight the unique timbres of these instruments, while also surrounding them with complementary sounds from their respective traditions, including the Ethiopian saxophone, Egyptian ney, oud, and violin, and the bass guitar.
(14) (5) The Ney B-2 as-welded specimens produced satisfactory joints which did not benefit from heat treatment.
(15) Myers will be lead commissioner and be paid £800 a day; Manzie will have the title of managing director commissioner, with a salary of £160,000; Newsam will be children’s social care commissioner; and Ney and Kenny will be supporting commissioners.
(16) A 5-year clinical comparison between silver palladium alloys (Albacast and Ney 76) and gold alloy (Firmilay) was conducted.