(a.) Having the quality of acting upon or affecting the nerves; quieting nervous excitement.
(n.) A nervine agent.
Example Sentences:
(1) Elevated blood levels confirmed bromide intoxication in both the mother and infant secondary to chronic maternal bromide ingestion (Nervine).
Sedative
Definition:
(a.) Tending to calm, moderate, or tranquilize
(a.) allaying irritability and irritation; assuaging pain.
(n.) A remedy which allays irritability and irritation, and irritative activity or pain.
Example Sentences:
(1) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
(2) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(3) However, the degree of sedation caused by diphenhydramine was significantly greater than that caused by cimetidine (P = .0001).
(4) Although lorazepam and haloperidol produced an equivalent mean decrease in aggression, significantly more subjects who received lorazepam had a greater decrease in aggression ratings than haloperidol recipients; this effect was independent of sedation.
(5) Adverse outcomes were reported more frequently by consultant physicians, by those who 'titrated' the intravenous sedative, and by those who used an additional intravenous agent, but were reported equally frequently by endoscopists using midazolam and endoscopists using diazepam.
(6) Alterations in mean systolic blood pressure appeared to be modest, consisting of a 10 percent decrease from the control level, related to sedation, and a 10 percent rise from baseline during the procedure, associated with a concomitant mild tachycardia.
(7) We have evaluated the action of hypnotics on the sleep-wakefulness cycle in freely implanted rats during their maximally active period because it is easier to estimate the duration of the sedative effect.
(8) A survey into the current usage of tracheal tubes and associated procedures, such as various sedation regimes and antacid therapy, in intensive care units was carried out in Sweden by sending a questionnaire to physicians in charge of intensive care units in 70 acute hospitals which included seven main teaching hospitals.
(9) The results show that both drugs possess sedative, antispasmodic, antipyretic, antiinflammatory, cardiotonic and hypotensive effects, the strength of effect and toxicity being similar.
(10) This suggests that the fluphenazine-induced sedation is not mediated via its effect on brain NA content, but is possibly due to the effect of the drug on NA turnover rates in the brain.
(11) The introduction of non-sedating H1-selective antihistamine drugs and local corticosteroids has been an important therapeutic advance.
(12) Neither a sedative nor other side effects could be seen.
(13) Sedation was measured by asking the subjects to complete visual analog scales.
(14) Smoking behaviour, self-reported mood and cardiac activity were examined in 12 "sedative" and 12 "stimulant" smokers, defined using Mangan and Golding's questionnaire.
(15) Patients in the reference group used more sedatives and long-acting nitroglycerine and had a lower return-to-work rate during the study period.
(16) A prospective study of the necessity of sedation, or analgesia, or both in total colonoscopy was performed.
(17) Fifteen consecutive patients on peritoneal dialysis who complained of chronic sleep disturbance and requested sedative were selected.
(18) Sedative interaction between midazolam and morphine was found to have a tendency for synergism (interaction coefficient of 1.56, P greater than 0.05) with decreased individual variability in the sedative response to the combination.
(19) Both drugs were relatively well tolerated, but trimipramine had a sedative effect which proved troublesome in some patients.
(20) None of the patients required anaesthesia, analgesics or sedatives.