(n.) A notch cut crosswise in the shank of a type, to assist a compositor in placing it properly in the stick, and in distribution.
(n.) A broken or indented place in any edge or surface; nicks in china.
(n.) A particular point or place considered as marked by a nick; the exact point or critical moment.
(v. t.) To make a nick or nicks in; to notch; to keep count of or upon by nicks; as, to nick a stick, tally, etc.
(v. t.) To mar; to deface; to make ragged, as by cutting nicks or notches in.
(v. t.) To suit or fit into, as by a correspondence of nicks; to tally with.
(v. t.) To hit at, or in, the nick; to touch rightly; to strike at the precise point or time.
(v. t.) To make a cross cut or cuts on the under side of (the tail of a horse, in order to make him carry ir higher).
(v. t.) To nickname; to style.
Example Sentences:
(1) When irradiated circular DNA, previously nicked by T4 endonuclease V, is briefly exposed to elevated temperature, the DAN becomes susceptible to the action of exonuclease V, and pyrimidine dimers are selectively released.
(2) To a supporter at the last election like me – someone who spoke alongside Nick Clegg at the curtain-raiser event for the party conference during the height of Labour's onslaught on civil liberties, and was assured privately by two leaders that the party was onside about civil liberties – this breach of trust and denial of principle is astonishing.
(3) Nick Robins, head of the Climate Change Centre at HSBC, said: "If you think about low-carbon energy only in terms of carbon, then things look tough [in terms of not using coal].
(4) "For a few it will feel like having your wallet nicked with the mugger then handing you a few bob back to buy a pint.
(5) Moreover, nick-translated [32-P]-pCS75, which is a pUC9 derivative containing a PstI insert with L and S subunit genes (for RuBisCO) from A. nidulans, hybridizes at very high stringency with restriction fragments from chromosomal DNA of untransformed and transformed cells as does the 32P-labeled PstI fragment itself.
(6) Nick Mabey, head of the E3G climate thinktank in London, said without US action there were risks talks would stall.
(7) One enzyme (called all-type) can nick all eight base mismatches with different efficiencies.
(8) Edman degradation of the intact A subunit of Shiga toxin indicated that the A subunit was nicked between Ala253 and Ser254 to form A1 and A2 fragments linked by a disulfide bond.
(9) Facebook Twitter Pinterest Nick Clegg and the Liberal Democrats have suffered a dramatic slump in support as a result of their role in the coalition and are now barely ahead of the Greens with an average rating of about 8% in the polls.
(10) Nick Nuttall, a spokesman for UNEP, said the latest findings should encourage more governments to follow moves by some politicians to invest billions of dollars in clean energy and efficiency as a way of curbing greenhouse gases.
(11) After Paris, Europe may never feel as free again | Nick Cohen Read more On Friday evening six separate attacks took place across Paris in what the French president, François Hollande, described as an “act of war”.
(12) A Tory planning minister has admitted that the coalition's new wave of garden cities would not have to contain a single affordable home, despite Nick Clegg's claims that they would offer low-cost accommodation and help solve the UK's housing crisis.
(13) Nick Clegg, who chairs the cabinet's home affairs committee, is said to have backed May's proposed package.
(14) Nick Clegg sounded exasperated, but it is Lib Dem convention to let members make the party’s policies by democratic vote.
(15) Nick Clegg and Ed Miliband accepted the Tory idea of a royal charter to establish a new press regulatory body but insisted it be underpinned in statute and said there should be guarantees of the body's independence.
(16) These bands were radiolabelled by subjecting the DNA--protein complexes to nick--translation in the presence of [32P]--dCTP, followed by prolonged digestion with excess bovine DNase I. Amino acid sequence analysis shows that these bands contain DNase I.
(17) We had a brief conversation and I said to him he was acting from high honour here, and I said how sorry I was this wasn’t happening in three or four years time..because Barry is a man of honour..and I think he is a very capable premier and I think he has been missed.” Asked whether he had ever met Nick di Girolamo , the prime minister said both he and Mr di Girolamo attended a lot of functions, and “I don’t for a moment say I have never met him but I don’t recall it.” But former federal Liberal MP Ross Cameron sounded much more sceptical about O’Farrell’s memory lapse when speaking to Sky News.
(18) The Km values of the substrates for both native and nicked enzyme were identical, as was the state of aggregation (dimeric) of the two enzyme species.
(19) Repair not only implies the closing of DNA nicks, but very likely the degradation of the BLM molecules intercalated in the DNA interrupting the reactions responsible for the generation of free radicals.
(20) Replays cast doubt on the penalty decision, the ball having been touched by the Australian replacement scrum-half, Nick Phipps, before the referee, Craig Joubert, adjudged the Scottish prop Jon Welsh caught it while standing in an offside position.
Notch
Definition:
(n.) A hollow cut in anything; a nick; an indentation.
(n.) A narrow passage between two elevation; a deep, close pass; a defile; as, the notch of a mountain.
(v. t.) To cut or make notches in ; to indent; also, to score by notches; as, to notch a stick.
(v. t.) To fit the notch of (an arrow) to the string.
Example Sentences:
(1) The Notch locus in Drosophila encodes a transmembrane protein required for the determination of cell fate in ectodermal cells.
(2) Recent reports have indicated the usefulness of nuclear grooves (clefts or notches) as an additional criterion for the diagnosis of papillary thyroid carcinoma in fine needle aspirates; most of these studies were carried out on alcohol-fixed material stained with the Papanicolaou stain or with hematoxylin and eosin, which yield good nuclear details.
(3) For histometric evaluation, the radicular notches were used as reference points.
(4) Conversely, in 66 of 80 pregnancies the absence of a notch was associated with the livebirth of an infant beyond 32 weeks gestation, with a birthweight above the 5th centile.
(5) The left subclavian artery was prominent in 33 cases, signs indicating a collateral circulation (rib notching, internal mammary artery) were present in 26 cases.
(6) Notched tympanograms were typical of neonatal ears for a 220-Hz probe tone.
(7) Radiographic manifestations include endosteal sclerosis of the neurocranium with loss of the diploë, osteosclerosis and hyperostosis of the mandible with absence of the normal antegonial notches, endosteal sclerosis of the diaphyses of long bones (including metacarpals and metatarsals), and osteosclerosis of the pelvis.
(8) For the experimental studies, fractures of the jaw bone in terms of oblique osteotomies from angle to sigmoid notch of the mandible of the Malaysian monkeys were made by using #700 fissure bur and reduced and fixed them in terms of interosseous wiring.
(9) Lymphadenopathies were classified by the criteria proposed by Yoshinaka et al., type I: poorly-defined borders, diffuse internal echoes; type II: well-defined borders, diffuse internal echoes; type III: well-defined borders, notchings, strong internal echoes.
(10) Here, we examine a group of six recessive mutations, the facets (fa, fa3, fag, fag-2, fafx and fasw), which affect eye and optic lobe morphology and have been previously shown to be associated with the insertion of transposable elements into an intronic region of Notch.
(11) Another frequent finding was partial or total obstruction at the tentorial notch, often in combination with reduced or absent activity along the superior sagittal sinus.
(12) In one patient, the fibrous band extended from the distal pole of the patella to the intracondylar notch, tethering the patella inferiorly.
(13) This thin flap, usually extending from the hyoid bone to the sternal notch at the central part of the anterior neck, provides a skin island of about 4 by 8 cm.
(14) The chest roentgenographic findings in Takayasu's arteritis include widening of the ascending aorta, contour irregularities of the descending aorta, arotic calcifications, pulmonary arterial changes, rib notching, and hilar lymphadenopathy.
(15) In two cases the epidermoid, located mainly in the cerebello-pontine angle, spread into the middle cranial fossa; in three the epidermoid extended from the parasellar cisterns to the posterior cranial fossa; in six patients the epidermoid, enlarging the tentorial notch, occupied extensively both cranial fossae.
(16) This post-transcriptional regulation is suppressed in embryos mutant for the genes Notch and Delta; where all cells expressing RNA accumulate protein.
(17) The femoral intercondylar notch width was measured in 93 patients with chronic anterior cruciate ligament (ACL) insufficiency (Group 1), in 62 patients with an acute tear of the ACL (Group 2), and in 38 fresh anatomic specimen knees (Group 3).
(18) Deep notch cases had more retrusive mandibles with a shorter corpus, smaller ramus height, and a greater gonial angle than did shallow notch cases.
(19) The acicular alpha structure has been shown to exhibit the best fatigue properties for Ti-6A1-4V alloy in the notched condition.
(20) The anatomical relations of the semilunar notch of the ulna were studied in radiographs, taken in a strict lateral view, from 100 patients with elbow dislocations.