(n. & a.) Nothing; of no account; worthless; -- a term often used for canceling, in accounts or bookkeeping.
Example Sentences:
(1) We have examined the presence of 5-hydroxytryptamine (serotonin; 5-HT) in the intermediate lobe of the frog pituitary and investigated the effect of exogenous 5-HT on alpha-melanocyte-stimulating hormone (alpha-MSH) release from the perifused neurointermediate lobe (NIL).
(2) Two injections of the alpha 1-adrenoceptor blocker prazosin 45 and 90 min before sacrifice, alone or together with the beta-blocker propranolol, prevented the increase in plasma AVP found in SCGx rats 6 h after surgery, and the decrease in plasma AVP and the increase of NIL-AVP found 16 h after SCGx.
(3) The incidence of G-6-PD varied from nil to 17.3%, while that of Hb-S varied from nil to 22.3%.
(4) The basal release of beta-END from NIL was 180% of that from HNC (p less than 0.01), which provides further support for the presence of hypothalamic factors that inhibit beta-END release from the intermediate pituitary.
(5) Hamster (nil) cells maintained overnight in culture medium containing cyclohemiximide and either glucose or fructose exhibit strikingly different rates of hexose transport and metabolism (i.e.
(6) Regardless of the sort of driving force, ATP synthesis was optimum at the intravesicular pH of around 6.5 and almost nil at 8, where ATP syntheses by F0F1 type ATPases in other organisms are most active.
(7) Only the private bank is willing to accept personal guarantees.” Deutsche Bank's $630m Russian fine reflects badly on banking | Nils Pratley Read more In the years since then, Deutsche Bank has been hit by scandal after scandal.
(8) He will not have to buy the shares – they are what are termed in the City "nil cost options" – but they will be awarded depending on the firm's financial performance.
(9) The amount of apo TC II produced by six lines of cultured human cells ranged from abundant to nil.
(10) 14C galactose incorporation into the TCA-precipitable material of cultures of fibroblasts deficient in galactokinase (GALK-) was nil.
(11) There were 8 black patients and 5 white; 10 had a biopsy diagnosis of focal segmental glomerulosclerosis (FSGS) and 3 nil lesion.
(12) Between December 1981 and December 1988 we treated 160 patients in this way, the mortality in the series being nil.
(13) The opiate receptor antagonist naloxone (1 microM) had no effect on the evoked release of 5-HT from the NIL or NL.
(14) The distribution of the gestagen given with EE revealed by the whole body autoradiography in normal mice were essentially consistent with the radiometric results in rats and that in the pregnant mice showed that the gestagen in fetus was virtually nil under the present conditions.
(15) 5-HT release evoked by electrical stimulation of the pituitary stalk from the NIL, but not from the isolated neural lobe (NL) was enhanced in the presence of the dopamine receptor antagonist sulpiride (1 microM).
(16) Fertility (fertile eggs per 100 set) and hatchability (live chicks per 100 fertile eggs) were both nil in the borate-treated hens, compared with 57 and 95 and 59 and 100 for the control and aluminate-treated hens, respectively.
(17) In all three cases, jejunal secretion rate of immunoglobulin A was nil and secretion rates of albumin and immunoglobulin G were increased as compared to controls.
(18) Oxytocin levels increased in the paraventricular nucleus and median eminence following NIL-X, whereas vasopressin concentrations were relatively unaffected by NIL-X.
(19) Severe undernourishment was not as effective as diabetes to reduce beta-END stores in the hypothalamus and NIL.
(20) Measurement of anterior and neurointermediate (NIL) pituitary BE-LI, alpha-MSH and ACTH and plasma corticosterone confirmed earlier results showing NIL depletion of all 3 peptides at 24 h and increased plasma corticosterone concentrations at 72 h in ethanol-exposed mice.
Til
Definition:
(prep. & conj.) See Till.
Example Sentences:
(1) Analysis of lymphocyte subsets by flow cytometry demonstrated Leu 4, 43.6% (T cells); Leu 10, 10.5% (B cells) and Leu 7, 13.1% (natural killer (NK) cells) in TIL.
(2) With one exception none of the purified CD4+ or CD8+ TILs expressed any significant levels of CD56, while the unseparated TILs contained varying numbers of CD3+CD56+ and CD3-CD56+ populations.
(3) Furthermore, it was also confirmed that TIL-LAK cells could be induced in autochthonous mouse tumor systems and human gastric tumor systems.
(4) However, IL-4 did not alter the cytotoxic activity of TILs against autologous tumor cells and established tumor cell lines.
(5) I'm here to defend her 'til the end even if they put me in jail."
(6) PFP immunoreactivity in human peripheral blood lymphocytes (PBL) and tumour infiltrating lymphocytes (TIL) was investigated immunocytochemically with the aid of an anti-PFP monoclonal antibody.
(7) TIL grown in the presence of IL-4 significantly reduced the level of non-specific, non-major histocompatibility complex-restricted antitumor activity (P < 0.01 for allogeneic renal, nonrenal, and NK-sensitive K562 cells), while exhibiting no effect on the level of autologous killing.
(8) In contrast, immune T cells (including some TIL) are MHC-restricted, act under the direction of memory cells and lyse target cells primarily but not exclusively by the release of lymphotoxin (TNF beta) causing programmed cell death (apoptosis) through endonuclease activation and target cell DNA fragmentation.
(9) Much has been learned about TIL biology and their functional characteristics recently, but only few clinical trials have been completed to date.
(10) Tumor-infiltrating lymphocytes (TIL) from human pulmonary tumors have been studied as a model for local depression of cell-mediated immunity at the tumor site.
(11) Phenotypic analysis of expanded TIL and two clones further analyzed in more detail showed CD3+, CD4+, CD8-, and 2H4+ (CD45R+) expression.
(12) The studies demonstrate the feasibility of TILs as suitable cellular vehicles for the introduction of therapeutic genes into patients receiving autologous TILs.
(13) High levels of activity were exhibited by TIL against both P815, which is resistant to natural killer (NK) cells, and to NK-sensitive YAC-1 cells.
(14) To improve the potency of TILs, new cytokines with T-cell stimulatory effects used alone or in combination with interleukin-2 (IL-2) are currently being investigated.
(15) On the other hand, TIL derived from the 2 patients whose melanoma cell lines had lost expression of HLA-A2 had a predominant CD4 phenotype and virtually no cytotoxic activity.
(16) These observations may imply the possibility of adoptive immunotherapy using TIL against human primary liver tumors.
(17) Titration of K562 targets in a 51Cr release assay revealed that untreated TIL have low cytotoxicity (4.32%) compared to untreated PBL (34.3%, P = less than 0.001).
(18) Dominant rearrangements of T-cell receptor (TCR) beta-chain genes are reported among tumor-infiltrating lymphocytes (TIL).
(19) This augmentation of TIL-mediated antitumor activity was dependent on the dose of radiation used.
(20) Those TIL expressing activation antigens were CD2+, SIg-.