(a.) Of, pertaining to, or containing, nitrogen; specifically, designating any one of those compounds in which, as contrasted with nitrous compounds, the element has a higher valence; as, nitric oxide; nitric acid.
Example Sentences:
(1) EDRF is even more labile than prostacyclin, with a half-life of about 6 seconds, and it has recently been identified as nitric oxide.
(2) Endothelium-dependent relaxations to acetylcholine and endothelium-independent relaxations to nitric oxide were observed in rings from both strains during contraction with endothelin.
(3) Inhibitors of nitric oxide synthase (NOS) have been reported to increase mean arterial pressure in animal models of sepsis and recently have been given to patients in septic shock.
(4) Nitric oxide (NO) is a major component of endothelium-derived relaxing factor (EDRF) the synthesis of which from L-arginine can be inhibited by NG-monomethyl-L-arginine (L-NMMA).
(5) Nitric oxide (NO) induced tetrodotoxin-resistant NANC relaxation, similar to that induced by electrical stimulation or acetylcholine (ACh).
(6) The distribution of nitric oxide synthase (NOS) immunoreactivity was investigated in the guinea-pig small intestine.
(7) Carbon monoxide accelerates the reaction as measured by nitric oxide oxidation or ozone formation.
(8) Considerable evidence has recently been presented that suggests that nitric oxide (NO) is a nonadrenergic noncholinergic (NANC) neurotransmitter in gastrointestinal tissues.
(9) The results indicate that cytokines induce a nitric oxide-synthase of the macrophage-type in vascular smooth muscle.
(10) For comparison we investigated several structural analogues with respect to their nitric oxide or nitrite ion releasing potency.
(11) To investigate this discrepancy we studied the role of nitric oxide (NO) in DCFH oxidation.
(12) Endogenous nitric oxide thus selectively modulates peptidergic neurotransmission in the gut.
(13) Nitroglycerin (glyceryl trinitrate) is a substance that is metabolized to nitric oxide in the cell.
(14) The role of the endothelium-derived vasodilator, nitric oxide, as a mediator of the increase in gastric mucosal blood flow and as a modulator of the acid secretory response induced by pentagastrin was investigated in the anesthetised rat.
(15) Endothelium-derived relaxing factor has been tentatively identified as nitric oxide (NO) partially on the basis of chemical assays.
(16) Nitric acid and elastase were injected into the tracheae of Wistar white rats and the effect of bronchiolitis on the pathogenesis of experimental emphysema and cor pulmonale was studied.
(17) The effectiveness of L-NMMA in blocking NANC relaxation-in the rat anococcygeus but not the BRP and bovine penile artery suggests a species difference in the neuronal nitric oxide synthase.
(18) Thus, inhibition of nitric oxide synthesis leads to long-lasting, but reversible, hypertension.
(19) The constrictor response to L-NNA and the blockade of the ACh-induced relaxation by both L-NNA and removal of endothelium are consistent with an involvement of nitric oxide.
(20) Nitric oxide synthase has now been purified and molecularly cloned from brain.
Nitrous
Definition:
(a.) Of, pertaining to, or containing, niter; of the quality of niter, or resembling it.
(a.) Of, pertaining to, or designating, any one of those compounds in which nitrogen has a relatively lower valence as contrasted with nitric compounds.
Example Sentences:
(1) Arterial oxyhaemoglobin saturation (SaO2) was monitored continuously during normal labour in 33 healthy parturients receiving pethidine and nitrous oxide for analgesia.
(2) Nitrous oxide, 60% (P less than 0.025) and 80% (P less than 0.02), caused significant increases in release of beta-endorphin.
(3) In the present work, we measured the inactivation of methionine synthase and the concurrent homocysteine export rate of two murine and four human cell lines during nitrous oxide exposure.
(4) Anaesthesia was achieved by a mixture of oxygen, nitrous oxide and fluothane without use of muscle relaxants.
(5) The purity and configuration of each isomer of the free acid and N-chloroacetylated derivative were ascertained by: (a) paper chromatography in five solvent systems, (b) elemental analysis, (c) Van Slyke nitrous acid determination of alpha-carbonyl carbon, and (d) Van Slyke ninhydrin determination of alpha-carbonyl carbon, and (e) optical rotation.
(6) The cardiorespiratory effects of trichloroethylene supplementation of nitrous oxide-oxygen anesthesia, with simultaneous use of halothane at induction as needed, were studied in outpatient oral surgery patients undergoing dental extractions under general anesthesia.
(7) The interactions of nitrous oxide with cytochrome c oxidase isolated from bovine heart muscle have been investigated in search of an explanation for the inhibition of mitochondrial respiration by the inhalation anesthetic.
(8) Nitrous oxide (N2O) is frequently used for maintenance of anesthesia in research animals because of its minimal effect upon circulatory variables and the ability to rapidly alter its anesthetic concentration.
(9) Nitrous oxide produced a dose-related analgesic response in rats (ED50, 67%) as measured by the tail-flick method.
(10) Cryotherapy with high-flow nitrous oxide was applied to the lid margin for 45 seconds in a freeze-thaw-freeze cycle.
(11) Such disturbances may be induced by opiates, benzodiazepines, phenothiazines, butyrophenones, ketamine, etomidate, propofol, nitrous oxide, and halogenated inhalation anesthetics as well as by H2-blocking agents such as cimetidine.
(12) For all personnel the geometric mean (GM) time-weighted average (TWA) exposures to halothane and nitrous oxide over the working period were 2.6 ppm (range: less than 0.5 119 ppm) and 100 ppm (range: 14-1700 ppm), respectively.
(13) Postoperative nausea and vomiting have been associated with the use of intravenous narcotics, and nitrous oxide may worsen the emetic effects of narcotics.
(14) The mechanism and time course of nitrous oxide-induced intratympanic pressure changes are described and contrasted with the effects of non-nitrous oxide anaesthesia.
(15) Using 14C-labelled nitrous bases as starting substrates, labelled nucleosides and nucleotides can be obtained with the 75-80% yield that have radioactive purity of 95-99%.
(16) In 14 sets of experiments, normal human lymphocytes stimulated with phytohemagglutinin on day 0 were exposed to nitrous oxide and oxygen on day 2.
(17) The authors advocate an active multimodality treatment of patients who developed seizures for the first time, the therapeutic and diagnostic use of pneumoencephalography with the administration of nitrous oxide into the cerebrospinal fluid.
(18) Rats injected with leukemic cells and exposed to nitrous oxide for 10 days showed 30% reduction of hepatosplenomegaly and 50% reduction of leukocytosis.
(19) Exposure to nitrous oxide produced concentration-dependent analgesia in the mouse abdominal constriction test.
(20) Chondroitinase ABC, nitrous acid, and heparinase degraded approximately 76%, 17%, and 7%, respectively, of the HBM-M cell-derived 35S-labeled proteoglycans.