(a.) According to an established norm, rule, or principle; conformed to a type, standard, or regular form; performing the proper functions; not abnormal; regular; natural; analogical.
(a.) According to a square or rule; perpendicular; forming a right angle. Specifically: Of or pertaining to a normal.
(a.) Standard; original; exact; typical.
(a.) Denoting a solution of such strength that every cubic centimeter contains the same number of milligrams of the element in question as the number of its molecular weight.
(a.) Denoting certain hypothetical compounds, as acids from which the real acids are obtained by dehydration; thus, normal sulphuric acid and normal nitric acid are respectively S(OH)6, and N(OH)5.
(a.) Denoting that series of hydrocarbons in which no carbon atom is united with more than two other carbon atoms; as, normal pentane, hexane, etc. Cf. Iso-.
(a.) Any perpendicular.
(a.) A straight line or plane drawn from any point of a curve or surface so as to be perpendicular to the curve or surface at that point.
Example Sentences:
(1) Patients with normal echocardiogram and ECG on admission do not require intensive care monitoring.
(2) Homozygotes have sparse greasy fur and lower viability and fertility than normal littermates.
(3) Of the patients 73% demonstrated clinically normal sensibility test results within 23 days after operation.
(4) One hour after direct mechanical cardiomassage (DMCM) a moderately pronounced edema of the intercellular spaces in the basal compartment of the seminiferous epithelium, normal content of lactate and succinate dehydrogenases, and a certain decrease in the activity of glucose-6-phosphate dehydrogenases and NAD- and NADP-diaphorases were noted.
(5) Electronmicroscopical investigations have revealed that, under normal conditions, a minor vesicular transfer of intravenously injected peroxidase occurs across the endothelium in segments of arterioles, capillaries and venules, especially in arterioles with a diameter about 15-30 mu.
(6) Of 19 patients with coronary artery disease and "normal" omnicardiograms, only 8 (42%) had normal ventricular angiography.
(7) Tests showed the cells survive and function normally in animals and reverse movement problems caused by Parkinson's in monkeys.
(8) The goals in control patients were to attain normal values for all hemodynamic measurements.
(9) The main finding of this study is that diabetic adolescents with a high erythrocyte Na,Li countertransport rate have an arterial pressure significantly higher than patients with normal Na,Li countertransport fluxes.
(10) The 14C-aminopyrine breath test was used to measure liver function in 14 normal subjects, 16 patients with alcoholic cirrhosis, 14 alcoholics without cirrhosis, and 29 patients taking a variety of drugs.
(11) In the past, the interpretation of the medical findings was hampered by a lack of knowledge of normal anatomy and genital flora in the nonabused prepubertal child.
(13) Despite their absence, photoreceptors maintained a normal rate of OS assembly.
(14) Early stabilisation may not ensure normal development but even early splinting carries a small risk of avascular necrosis.
(15) Other haematological parameters remained normal, with the exception of the absolute number of lymphocytes, which initially fell sharply but soon returned to, and even exceeded, control levels.
(16) It was the purpose of the present study to describe the normal pattern of the growth sites of the nasal septum according to age and sex by histological and microradiographical examination of human autopsy material.
(17) In addition, KM231 could detect a small amount of the antigen ganglioside in human gastric normal and cancerous mucosa and in gastric cancer cell lines by HPTLC-immunostaining.
(18) The results indicate that OA-bearing macrophages primed T cells and generated helper T cells, whereas the culture of normal lymphocytes with soluble OA in the absence of macrophages generated suppressor T cells.
(19) In hypophysectomized rats the activity of alanine aminotransferase was increased, but its normal zonation (predominance in the periportal zone) was preserved.
(20) Five of the nine normal livers had peribiliary glands that showed HLA-DR.
Substituent
Definition:
(n.) Any atom, group, or radical substituted for another, or entering a molecule in place of some other part which is removed.
Example Sentences:
(1) Replacement of vinyl groups with bulkier substituents (hydroxyethyl or acetyl groups) decreases holoenzyme stability and catalytic activity.
(2) The molar refractivity has been shown to be a superior parameter for the description of the activity of sulphonamides than the sum of electronegativities of atoms making up a heterocyclic substituent in the sulphonamide molecule and molecular weight of the substituent.
(3) Energy conformational calculations on these compounds were also carried out using the empirical energy program called MOLMEC, in order to better understand how the 4-R substituents modulate receptor binding affinities and efficacies.
(4) The N-substituents included methyl, benzyl, and beta-hydroxy- and beta-chloroethyl groups.
(5) Substitution at the 5'-position resulted in decreased efficacy as inhibitors of uridine kinase, particularly if the substituent was large.
(6) Enzyme-inhibiting ability for individual alkylphenols can be estimated based on the quantitative structure-activity relationship developed by Dewhirst (1980) and is a function of the free hydroxyl group, electron-donating ring substituents, and hydrophobic aromatic ring substituents.
(7) All other broad-spectrum benzimidazole anthelmintics, regardless of substituent at the 2 position (methyl carbamate or thiazolyl group), are flat.
(8) Difference spectra for the tetracyclines were dependent on the characteristics of the ring substituents.
(9) Activity was insensitive to oxygen and CO if the substrates had no additional substituents on either ring or contained only electron-donating substituents.
(10) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(11) The ability of the monocarboxylate analogues to inhibit depends strongly on the nature of substituents, particularly at the second carbon.
(12) The receptor subregion that interacts with the propyl C-1 of 1 is more tolerant of bulk and of polar substituents than the subregion that interacts with propyl C-3.
(13) The relative reactivities of three o-substituted phenols can be explained in terms of steric hindrance which is minimal for a single o-substituent.
(14) Sucrose esters were prominent surface constituents and 3-methylvaleric acid, 2- and 3-methylbutyric acid, and methylpropionic acid accounted for 60%, 25% and 9%, respectively, of total C3--C7 acyl substituents.
(15) In compounds with other substituents that promote activity, C-6 alpha substitution with -CH3, -Cl, or -Br strongly enhances activity; -F, -OCH3, carbonyl, or the unsubstituted compound promotes weak binding; and -OC2H5, -OAc, -OCOOCH3, or -OH eliminates binding activity.
(16) The hypoprothrombinemia in vitamin K-deficient female rats was caused by beta-lactam antibiotics with N-methyltetrazolethiol, thiadiazolethiol and methyl-thiadiazolethiol as the 3'-position substituent of the cephem nucleus.
(17) After prolonged adaptation of strain BN6 to growth on 6A2NS, this organism readily converted all naphthalene-2-sulfonates with OH- or NH2-substituents in the 5-, 6-, 7-, or 8-position.
(18) Six new 5(1H)oxo-2,3-dihydroimidazo[1,2-a]pyrimidine-6-carboxylic ethyl esters bearing an aromatic substituent in position 1 or 2 were obtained.
(19) This radioligand was selected as a synthetic target because of its potency as a 5HT3-receptor antagonist, its selectivity for this receptor viz a viz other 5HT-receptor subtypes, and the ability to readily incorporate three tritia via the indazole N-CH3 substituent.
(20) Instead, the latter experiment yielded 1,5-anhydro-2,3-di-O-methyl-D-mannitol, establishing the presence in the polysaccharide of terminal (nonreducing) D-mannopyranosyl groups bearing 4,6-O-(1-carboxyethylidene) substituents.