(n.) An elastic cartilagelike rod which is developed beneath the medullary groove in the vertebrate embryo, and constitutes the primitive axial skeleton around which the centra of the vertebrae and the posterior part of the base of the skull are developed; the chorda dorsalis. See Illust. of Ectoderm.
Example Sentences:
(1) The histochemical study of the LDH in the Trout embryo during the early organogenesis shows a specific localization in notochord cells, in mesodermic cells of the terminal knob and in some prosencephalic neuroblasts.
(2) The notochord, which is composed of a stack of flat cells surrounded by a connective tissue sheath, elongates dramatically and begins straightening between stages 21 and 25.
(3) Autoradiographic studies show that tritiated proline is taken up by notochordal cells and secreted to the extracellular space where label is associated with basal lamina, microfibrils and ground substance.
(4) Metabolic events in somites related to hyaluronic acid are not influenced by the notochord.
(5) The establishment of myeloschisis was followed by local separation of the notochord from an open area of neural tube, but not by overgrowth of neural tissue.
(6) By 7 days, notochordal uptake is markedly diminished, and no uptake of isotope occurs from 8 days onward.
(7) It first forms on the lateral portion of the neuroepithelium of the neural folds and then extends ventrally into the region adjacent to the notochord; (ii) BL becomes continuous beneath the epidermal ectoderm (EE) that overlies the NC cell region only during the terminal stages of NC cell emigration; (iii) BL does not form over the dorsal portion of the neural tube until NC emigration is terminated; and (iv) the morphology of the BL changes as development proceeds.
(8) Although they are presumed to arise from congenital notochordal remnants, it is rare for these tumors to present in childhood.
(9) Six chordomas, ten fetal notochords and eight adult notochords were stained for keratin, vimentin, GFAP, desmin, CEA, EMA and s-100 protein.
(10) A "diffuse pattern" that was seen in the histological appearance of 4 cases of the chordoma, including 2 cases with metastases, was not observed in the notochord and was considered to indicate the malignant nature of such chordoma.
(11) The results lead to the assumption that the early embryos already possess cholinergic receptors, probably located in the notochord.
(12) Adjacent to the caudal half of each somite, these cells penetrated no further than the myosclerotomal border, but opposite the rostral somite half, they were found next to the sclerotome almost as far ventrally as the notochord.
(13) These results indicate that 1) Engrailed-2 expression is suppressed in the most ventral neural tube owing to induction of the floor plate by the notochord, and 2) that the presence of an underlying notochord is not required for correct rostrocaudal expression, suggesting that multiple pathways act in the patterning of the rudiment of the central nervous system.
(14) Neural induction through the presumptive notochord was tested by means of the sandwich method.
(15) The notochord and neural tube are well developed by 3 days and surrounded by sclerotome, myotome, and dermatome cells.
(16) Minute fragments of the notochord of Balanoglossus sp.
(17) Glycosaminoglycans (GAG) are found primarily in the dorsal fin and in the ECM surrounding the notochord.
(18) Based on these facts, it is to be concluded that it is not the inducer of notochord, but the surrounding mesenchyme that is of primary importance for the determination of the types of neural tissue.
(19) A floor plate-specific chemoattractant was used as a marker to examine the role of the notochord in avian floor plate development.
(20) 2G9 was used to show that both notochord and somites are capable of neural induction, and the stimulus is present as late as stage 22.
Spin
Definition:
(v. t.) To draw out, and twist into threads, either by the hand or machinery; as, to spin wool, cotton, or flax; to spin goat's hair; to produce by drawing out and twisting a fibrous material.
(v. t.) To draw out tediously; to form by a slow process, or by degrees; to extend to a great length; -- with out; as, to spin out large volumes on a subject.
(v. t.) To protract; to spend by delays; as, to spin out the day in idleness.
(v. t.) To cause to turn round rapidly; to whirl; to twirl; as, to spin a top.
(v. t.) To form (a web, a cocoon, silk, or the like) from threads produced by the extrusion of a viscid, transparent liquid, which hardens on coming into contact with the air; -- said of the spider, the silkworm, etc.
(v. t.) To shape, as malleable sheet metal, into a hollow form, by bending or buckling it by pressing against it with a smooth hand tool or roller while the metal revolves, as in a lathe.
(v. i.) To practice spinning; to work at drawing and twisting threads; to make yarn or thread from fiber; as, the woman knows how to spin; a machine or jenny spins with great exactness.
(v. i.) To move round rapidly; to whirl; to revolve, as a top or a spindle, about its axis.
(v. i.) To stream or issue in a thread or a small current or jet; as, blood spinsfrom a vein.
(v. i.) To move swifty; as, to spin along the road in a carriage, on a bicycle, etc.
(n.) The act of spinning; as, the spin of a top; a spin a bicycle.
(n.) Velocity of rotation about some specified axis.
Example Sentences:
(1) Type 1 changes (decreased signal intensity on T1-weighted spin-echo images and increased signal intensity on T2-weighted images) were identified in 20 patients (4%) and type 2 (increased signal intensity on T1-weighted images and isointense or slightly increased signal intensity on T2-weighted images) in 77 patients (16%).
(2) Electron spin resonance studies indicate the formation of two vanadyl complexes that are 1:1 in vanadyl and deferoxamine, but have two or three bound hydroxamate groups.
(3) The relative rates of reduction of several spin-labeled molecules that partition differently across the hy-drophobic-interface of inner membranes from rat liver mitochondria were investigated.
(4) When reformist industrialist Robert Owen set about creating a new community among the workers in his New Lanark cotton-spinning mills at the turn of the nineteenth century, it was called socialism, not corporate social responsibility.
(5) An unusually high degree of motional freedom is found for both these spin-labels, even in gel phase bilayers.
(6) tert-Butyl hydroaminoxyl is detected as a degradation product of the hydroxyl adduct from all spin traps.
(7) After the first stage of analysis the spin systems of 60 of the 77 residues were assigned to the appropriate residue type, providing an ample basis for subsequent sequence-specific assignments.
(8) A method using selective saturation pulses and gated spin-echo MRI automatically corrects for this motion and thus eliminates misregistration artifact from regional function analysis.
(9) The Iranians have accused the Israelis and the US of designing and deploying Stuxnet, which set some of their centrifuges spinning out of control.
(10) Single vertical spin and electron microscopy analyses of these HDL subpopulations demonstrated that acid elution from the affinity columns caused no detectable change in size and density of the three subpopulation particles.
(11) The Soret MCD of the reduced protein is interpreted as th sum of two MCD curves: an intense, asymmetric MCD band very similar to that exhibited by deoxymyoglobin which we assign to paramagnetic high spin cytochrome a3(2+) and a weaker, more symmetric MCD contribution, which is attributed to diamagnetic low spin cytochrome a2+.
(12) For dipeptides containing the amino terminal residues glycine, alanine and phenylalanine, abstraction of the hydrogen from the carbon adjacent to the peptide nitrogen was the major process leading to the spin-adducts.
(13) A single spin density gradient ultracentrifugation method in a swinging bucket rotor has been applied for the detection and isolation of low density lipoprotein (LDL) subfractions.
(14) In addition to rapid motions, slow motions were detected by 1H spin-lattice relaxation time in the rotating frame (TH1 rho) and cross-polarization time (TCH), together with data from static spectra, indicating that the aliphatic portion of the detergent interacts more strongly with hydrophobic protein surfaces than do the polar heads.
(15) In addition, the spin lattice relaxation time of the cytoplasmic Cs resonance was approx.
(16) 220 MHz proton Fourier transform (FT) NMR with quadrature phase detection (QPD) technique is applied to observe largely hyperfine-shifted signals of various hemoproteins and hemoenzymes in ferric high-spin state.
(17) Under aerobic conditions, electron spin resonance spectroscopy showed evidence for the production of AZQ semiquinone (AZQH) and oxygen radicals.
(18) With these compounds, the spin density at the nitro group was greater than with nifurtimox, nitrofurazone and nitrofurantoin.
(19) Probing of the active site of microsomal cytochrome P-450 was carried out with a spin label derived from 2-methyl-1,2-bis(3-pyridyl)-1-propanone (metyrapone).
(20) The electronic structure of the low-spin ferric iron in cyanide complex appears to be modulated by halide binding to a protonated amino acid in the distal heme cavity.