(prep.) Without prevention, or obstruction from or by; in spite of.
(adv. / conj.) Nevertheless; however; although; as, I shall go, notwithstanding it rains.
Example Sentences:
(1) These data notwithstanding, the role of SIV genetic variation in the pathogenesis of AIDS in monkeys remains unclear.
(2) Notwithstanding the fact that rubella vaccination has been recommended for all school-girls since 1973, no significant difference was noticed between the seropositivity rates of healthy females aged 18-23 observed in the period 1973-78 (i.e.
(3) Articles in the popular press notwithstanding, data from the 1984 National Long-term Care Survey indicate that a relatively small number of adult children and spouses assume the multiple responsibilities of elder care and child care or employment.
(4) Notwithstanding, the short-term prognosis for typhlitis remains poor.
(5) The advantages of having two X chromosomes are apparent, notwithstanding X-chromosome inactivation.
(6) The paper proposes that in post-behaviouristic and post-phenomenological times an integration of frames of reference, designs and methodologies ought to be attempted, notwithstanding serious dissonances, disagreements, and professions-bound interests.
(7) Notwithstanding these differences, the positions of all the vocal folds in extreme adduction or abduction were similar.
(8) This section was memorably captured by the computer and security expert Caspar Bowden , who wrote: "Interpreting that section requires the unravelling of a triple-nested inversion of meanings across six cross-referenced subsections, linked to a dozen other cross-linked definitions, which are all dependent on a highly ambiguous 'notwithstanding'."
(9) This is because determinants of flexion after TKA are multifactorial and outcome data limited, notwithstanding the similarities among modern prostheses.
(10) The success of Capote paved the way for bigger and more nuanced parts for Hoffman, his turn as the villain in Mission: Impossible III (2006) notwithstanding.
(11) Notwithstanding the complexities involved in the absorption processes, the data support the hypothesis that the absorption of organic electrolytes mainly takes place by the partitioning of the unionized species into the lipoidal membranes and then diffusion.
(12) These results, when viewed together with those reported in humans with ARDS and in dogs with ethchlorvynol-induced ALI, support the hypothesis that leukotriene detection in BALF is a feature common to ALI, etiology notwithstanding.
(13) Within selected planes, DRESS are spatially restricted by the surface coil sensitivity profiles to disk-shaped volumes whose radii increase with depth, notwithstanding variations in the NMR signal density distribution.
(14) Notwithstanding, each index can serve a useful role in quantitating method agreement in carefully considered situations.
(15) This means that notwithstanding a tight pay offer, total investment by the BBC in its people will go up.
(16) Labelled IGF-2 bound predominantly to the type 2 receptor with negligible label cross-linked to the type 1 receptor, notwithstanding the ability of IGF-2 to compete effectively for the binding of IGF-1 to the type 1 receptor.
(17) Notwithstanding important advances in the treatment of epilepsy basic knowledge about the epilepsies and about the mechanism of action of antiepileptic drugs is still fragmentary.
(18) Notwithstanding the latent benefits and cost savings that corporate management expects to gain from the investment in such programs, it is argued that workplace health promotion is not without potential misuse and that its goals and methods ought not to be above ethical scrutiny.
(19) This speech was designed to allow progressives once again to see Barack Obama as they have always wanted to see him, his policies notwithstanding: as a deeply thoughtful, moral, complex leader who is doing his level best, despite often insurmountable obstacles, to bring about all those Good Things that progressives thought they would be getting when they empowered him.
(20) In the course of an infectious episode and notwithstanding an increase in EPO dosage, 2 patients exhibited a fall in hemoglobin which rose again after successful treatment of the infection.
Spite
Definition:
(n.) Ill-will or hatred toward another, accompanied with the disposition to irritate, annoy, or thwart; petty malice; grudge; rancor; despite.
(n.) Vexation; chargrin; mortification.
(v. t.) To be angry at; to hate.
(v. t.) To treat maliciously; to try to injure or thwart.
(v. t.) To fill with spite; to offend; to vex.
Example Sentences:
(1) In spite of dense lymphocytic infiltration only 3% of the tumor infiltrating lymphocytes exhibit the activation marker CD 25.
(2) When labelled long-chain fatty acids or glycerol were infused into the lactating goat, there was extensive transfer of radioactivity into milk in spite of the absence of net uptake of substrate by the mammary gland.
(3) In spite of important differences in size, chemical composition, polymer density, and configuration, biological macromolecules indeed manifest some of the essential physical-chemical properties of gels.
(4) Mastitis in its complexity has managed to forestall all efforts of eradication in spite of years of research, antibiotics and practical control measures.
(5) In spite of antimalaria treatment, with cortisone and then with immuno-depressants, the outcome was fatal with a picture of acute reticulosis and neurological disorders.
(6) In spite of the presence of scar tissue following rhytidectomy, this procedure has been quite successful because of the rich blood supply in that area.
(7) By the GN of non-streptococcal etiology, AA's to the BLSE apparently of other specificity are obtained in some cases, in spite of the absence of antibodies to A-PS.
(8) In spite of the formation of the epoxide intermediate, no binding of [14C]d-limonene equivalents to mouse kidney proteins was observed.
(9) No cases of rheumatic fever and no acute nephritis appeared in spite of the vigorous immune response to both cellular and extracellular antigens of group A streptococci documented in 50% to 80% of patients, suggesting that strain variation may be a feature of rheumatogenicity as well as nephritogenicity of group A streptococcal pharyngitis.
(10) Clinical and inflammatory activity improved in both groups, but consistently more so in the auranofin group, in spite of the greater consumption of local steroids and NSAIDs in the placebo group.
(11) The reported case of fetal infection in spite of previous rubella vaccination of the mother does not discourage the use of rubella vaccine.
(12) Although operative mortality was significantly greater for women during most of this review period, mortality was similar during 1983 (2.6% for men versus 2.4% for women), in spite of a significantly higher incidence of unstable angina in the female group (54% for women versus 35% for men).
(13) The shapes of the curves for soleus and tibialis anterior are similar in spite of the different mechanical conditions of the two muscles.
(14) In spite of the limitations arising from the complex geometry of the right ventricule, echocardiography may be the most important non-invasive technique in the evaluation of the structural and functional repercussion of hypertension on the right ventricle.
(15) Thus, in spite of its excellent activity and unquestionable effectiveness, rifampicin should be used with caution in severe staphylococcal infections.
(16) My son was born healthy, strong and very handsome, in spite of his dangerous start.
(17) The great clinical value of the procedure is shown by the following findings:X-ray-negative lesions--including 2 cases of carcinoma--were found in 35 percent of the cases, radiologically demonstrated lesions could be defined more precisely in 18 percent, and the presence of colonic lesions could be ruled out in 11 percent in spite of equivocal X-ray findings.
(18) In spite of low fluoride content in their water supply, the findings revealed a generally low prevalence of caries experience (DMFT 1.26).
(19) In anesthetized cats, the enhancement of sympathetic activity and increase of the blood pressure in exclusion of afferents (section of vagosympathetic trunks and clamping of common carotid arteries) as well as the disappearance of the activity in enhanced afferentation, were shown to be transient and to disappear within a few minutes-scores of minutes in spite of the going on deafferentation or enhancement of afferentation.
(20) By modifying the spatial distribution of afferents to the network, we demonstrate that the same basic model functions properly in spite of afferents with nonuniform background firing rates.