(a.) Of recent origin or introduction; not ancient; new; hence, out of the ordinary course; unusual; strange; surprising.
(a.) That which is new or unusual; a novelty.
(a.) News; fresh tidings.
(a.) A fictitious tale or narrative, professing to be conformed to real life; esp., one intended to exhibit the operation of the passions, and particularly of love.
(a.) A new or supplemental constitution. See the Note under Novel, a.
Example Sentences:
(1) Moreover in MIT-1, the size of the novel polypeptide was not that predicted of the precursor (44.9 kDa) but was about 39 kDa, the same size as the authentic GS gamma polypeptide in CYT-4.
(2) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
(3) A novel prostaglandin E2 analogue, CL 115347, can be administered transdermally on a long-term basis.
(4) The lipid A moiety was shown to be responsible for this novel biological activity of the LPS molecule.
(5) Experiment 3 showed that the color-induced increase in odor intensity is not due to subjects' preexperimental experience with particular color-odor combinations, because the increase occurred with novel ones.
(6) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(7) But what they take for a witticism might very well be true; most of Ellis's novels tell more or less the same story, about the same alienated ennui, and maybe they really are nothing more than the fictionalised diaries of an unremarkably unhappy man.
(8) Cyclosporine is a fungal endecapeptide of novel chemical structure that causes preferential inhibition of T helper cells.
(9) As novel antibody therapeutics are developed for different malignancies and require evaluation with cells previously uncharacterized as antibody-dependent cell-mediated cytotoxicity (ADCC) targets, efficient description of key parameters of the assay system expedites the preclinical assessment.
(10) Her novels have an enduring and universal appeal and she is recognised as one of the greatest writers in English literature.
(11) The complex problems have been successfully managed with novel guiding catheter shapes and ultralow profile balloons.
(12) Moreover, the most recent combined application of the rat interstitial cell testosterone (RICT) bioassay and a novel multiple-parameter deonvolution model has allowed investigators to dissect plasma concentration profiles of bioactive LH into defined secretory bursts, which have numerically explicit amplitudes, locations in time, and durations, and are acted upon by determinable subject- and study-specific endogenous metabolic clearance rates.
(13) The extensive conversion of anti-BPDE to B[a]PT-10-sulfonate under conditions where sulfite enhances diolepoxide mutagenicity, when coupled with this enhancement of diolepoxide mutagenicity by B[a]PT-10-sulfonate in the reverse mutation assay, supports this novel B[a]P derivative as a mediator of the sulfite-dependent enhancement of B[a]P genotoxicity.
(14) This novel coumarin derivative significantly inhibited skin tumor initiation by DMBA in SENCAR mice when given at a dose of 200 nmol, 5 min (69% inhibition) or 24 h (76% inhibition) prior to initiation.
(15) Using a novel method for joining DNA sequences, we have exploited this difference between the two enzymes to identify the regions of the RT that contribute to the compounds' inhibitory activities.
(16) It may thus represent an artifact of the labeling procedure rather than a novel basophil-derived prostaglandin.
(17) Endothelin-1 (ET-1) is a novel vasoconstricting and cardiotonic peptide that is synthesized by the vascular endothelium.
(18) These observations indicated a novel mechanism that in the absence of light-dark schedule, mothers taught the circadian rhythm to the pups as they raised them.
(19) Pretreatment with a novel CRF antagonist, alpha-helical CRF9-41 (130.9 nmol i.t.v.
(20) Prions are novel, transmissible pathogens causing degenerative diseases of the central nervous system both in humans and in animals.
Picaresque
Definition:
(a.) Applied to that class of literature in which the principal personage is the Spanish picaro, meaning a rascal, a knave, a rogue, an adventurer.
Example Sentences:
(1) It makes up part of our legendary picaresque national character, and our weak culture of solidarity."
(2) "My writing is more influenced from the European side - the picaresque novel, but also for me there's Melville, and not only Moby Dick, and poetry from Walt Whitman, who've influenced European literature.
(3) Yet it suffers from an inconsistency of tone, an overly picaresque procession of events, and a general wooziness – perhaps imparted by the scorching Puerto Rican locations – that around the 60-minute mark induces an insidious siesta-time sleepiness in the viewer (well, this one, at least).
(4) Now read on Rupert Thompson's The Insult, with its combination of American picaresque and dreamlike alienation, is greatly influenced by Auster.
(5) This is the story of a picaresque journey in France and in Corsica of Jules Cloquet (1790-1883), the French anatomist who described the well-known Cloquet's node and of Gustave Flaubert (1821-1880), the famous author of "Madame Bovary" and of many others novels.
(6) This great American picaresque isn’t especially heavy on narrative force so it remains to be seen how playwright Jeffrey Hatcher and director David Esbjornson will propel the Big Easy action along.
(7) The others on the shortlist were Carol Birch for her much-admired Jamrach's Menagerie , a historical high seas adventure; two Canadian writers - Patrick deWitt for The Sisters Brothers , a picaresque western, and Esi Edugyan for Half Blood Blues , which mixes the raw beauty of jazz and the terror of Nazism; and two debut novels – Stephen Kelman for Pigeon English , which tells the story of a Ghanaian boy who turns detective on a south London housing estate; and AD Miller for Snowdrops , a Moscow-set tale of corruption and moral decline.
(8) But when all the daring connections and imaginative leaps coincide, such as in the Dragons' Trilogy, a picaresque exploration of Chinese culture, or in the seismic plotlines of Tectonic Plates, and Seven Streams, when it appeared again at the National in 1996 (after four years of public performances had refined it to perfection) the effect is spellbinding.
(9) Huck Finn itself is travel writing, in which the raft-trip down the Mississippi provides the picaresque structure for an episodic tale, an Edenic journey away from civilisation, as well as an occasionally frightening glimpse of the (all-too-human) wilderness.
(10) Sympathetic readers have actually regarded Holden as a saint, albeit of an unconventional kind, and have seen the plot as an exercise in the spiritual picaresque.
(11) This has been his special skill in the second half of a picaresque 23-job managerial career after an early ascent built on sturdy, workmanlike success.
(12) Some are gossipy and gonzo, like Bob Carr’s magnificently picaresque romp through the foreign affairs portfolio published earlier this year.
(13) Kim is at once spy story, coming-of-age tale, picaresque novel, adventure and a slice of Indian society at the end of the 19th century.
(14) Two more fat tomes followed: The Scar , a picaresque maritime adventure in which the city at the heart of the book is a floating community of ships lashed together by pirates; and Iron Council , a politically charged western in which a train hijacked by revolutionaries strikes out into the unknown.
(15) After Karadžić arrived in Serbia, the picaresque tale became even more bizarre.
(16) Critical verdict Auster's career has ranged from family memoir (The Invention of Solitude) to speculative dystopia (In The Country of Last Things), picaresque magical realism (Mr Vertigo), investigations of identity (The New York Trilogy established him as the only author one could compare to Samuel Beckett) and animal fable (Timbuktu).
(17) Now read on John Irving's picaresque epics (A Prayer for Owen Meany, The World According to Garp) are lighter than Grass's work, but share a similar tone (Irving studied under Grass in Vienna).
(18) The Secret History of Costaguana (2007), published this month by Bloomsbury in McLean's translation, is a humorous, picaresque novel of adventure and a knowing take on a family saga.
(19) The picaresques by which he drew self-deprecating parallels between himself and these figures were beautifully constructed.
(20) A sort of weird, sprawling picaresque epic, which starts out relatively small and gets larger.