(a.) Hurtful; harmful; baneful; pernicious; injurious; destructive; unwholesome; insalubrious; as, noxious air, food, or climate; pernicious; corrupting to morals; as, noxious practices or examples.
(a.) Guilty; criminal.
Example Sentences:
(1) At both 24 h and 1 week, the inflamed paw showed pronounced supersensitivity to the antinociceptive action of morphine against noxious pressure.
(2) "It looks as if the noxious mix of rightwing Australian populism, as represented by Crosby and his lobbying firm, and English saloon bar reactionaries, as embodied by [Nigel] Farage and Ukip, may succeed in preventing this government from proceeding with standardised cigarette packs, despite their popularity with the public," said Deborah Arnott, chief executive of the health charity Action on Smoking and Health.
(3) Noxious conditioning stimulation of a tooth led to a temporary decrease of the threshold for the jaw-opening reflex elicited from a contralateral or adjacent tooth; only conditioning stimulation at an intensity producing a marked arousal reaction was effective in this respect.
(4) Results showed the greatest inhibition of noxious stimulus perception with Innovar-Vet, lesser inhibition with ketamine-xylazine and ketamine-diazepam, and the least obtunding of nociception with pentobarbital.
(5) Furthermore the noxious stimuli were completely ineffective from 10-15 min following the lidocaine injection while the non-noxious stimuli maintained their efficacy.
(6) Experiments using normal human subjects were performed to determine the effect of a putative analgesic, transcutaneous electrical nerve stimulation (TENS), on the perception of noxious thermal stimuli and also to examine critically the general applicability of signal detection theory (SDT) to the evaluation of analgesic agents.
(7) Rats inoculated in the tail-base with killed Mycobacterium butyricum developed an arthritic swelling and inflammation of the limbs accompanied by a hyperalgesia to noxious pressure applied thereto.
(8) Complete transection of the thoracic spinal cord eliminated both thermally elicited responses and orienting responses to noxious and tactile mechanical stimulation of the hindlimbs.
(9) This situation has contributed to exposure of sandblasters to hazardous levels of respirable free silica, and is reviewed here to prevent a continuation of the incompatibility of these and other standards for respiratory protection with the actual exposures to various noxious inhalants in the workplace.
(10) Effects of noxious electrical tooth stimulations and intraarterial administration of bradykinin or inhalation of volatile anesthetics on substance P content in the diencephalon-mesencephalon, pons-medulla and the spinal cord were examined in the rat.
(11) Surface airway epithelium is frequently injured by noxious inhaled agents, epithelial wound repair may be an important process by which the epithelial barrier integrity is maintained.
(12) Cough and bronchoconstriction are airway reflexes that protect the lung from inspired noxious agents.
(13) Pb also appeared to unmask an afterdischarge in some neurons following noxious mechanical stimulation.
(14) Neurons were first classified as on-cells if they fired faster during noxious pinch or as off-cells if they fired slower.
(15) These data indicate the antinociception from PAG stimulation is not equally distributed throughout the body, and that the intensity of the noxious stimulus influences the threshold for SPA.
(16) Profound inhibitions of the second phase were also produced by tactile segmental stimulation and noxious stimuli applied to widespread areas of the body (diffuse noxious inhibitory controls).
(17) It hasn't been reported that the neurons in somatosensory area I (SI) may respond to the noxious stimulation.
(18) Stimuli used to activate the cells orthodromically were graded innocuous and noxious mechanical stimuli, including sinusoidal vibration and thermal pulses.
(19) This cannot be explained by metabolic activation of the halogenated hydrocarbons but could be due to a noxious effect on the mitotoc spindle.
(20) Suppression of the tail flick response to noxious heat and paw withdrawal response to noxious pressure were produced by electrical stimulation of arcuate nucleus of the hypothalamus (ARH) in pentobarbital anesthetized rats.
Obnoxious
Definition:
(a.) Subject; liable; exposed; answerable; amenable; -- with to.
(a.) Liable to censure; exposed to punishment; reprehensible; blameworthy.
(a.) Offensive; odious; hateful; as, an obnoxious statesman; a minister obnoxious to the Whigs.
Example Sentences:
(1) They occupy that weird middle ground between anonymity and celebrity; they're from well-regarded restaurants, but they're not at the level where, say, James Martin can be obnoxious at them on Saturday Kitchen.
(2) Only in recent years has serious attention been given to the control of chemotherapy-induced emesis (CIE) which is to the patient a most obnoxious side-effect.
(3) At the place where adorable meets obnoxious and the purr becomes a shriek, Leslie Mann is waiting to unload a howitzer of funny in your face.
(4) This paper describes examples of adolescent behavior which parents and school personnel find obnoxious.
(5) Beneath this, there is the obnoxious notion that people owe their employer loyalty, gratitude and even love; tug your forelock and go "the extra mile" for an employer who may show you no loyalty and dump you as soon as you become old, pregnant or sick.
(6) The interview, broadcast on 1 October, and the BBC's decision to invite the party's leader, Nick Griffin, on to Question Time next week indicated the BBC was "sadly succumbing" to those who "in Griffin's obnoxious words, 'defend rights for whites with well-directed boots and fists'," he adds.
(7) Perhaps it was because, despite being the first portable music player, it wasn't as easy to lug around as the MP3 player; its chunky dimensions compelled it to be worn clipped to a belt, creating the danger that it would unclip itself – which it did with obnoxious regularity – and crash to the ground, disgorging its batteries.
(8) If Mitchell may seem a little rebarbative to some tastes, he would have to try hard to be more obnoxious than John Tully, who has demanded his resignation .
(9) Echoing one of his most famous early speeches, Bin Laden told “brothers ... in the Islamic Maghreb” their job was “to uproot the obnoxious tree by concentrating on its American trunk”, and to avoid being occupied with the local security forces.
(10) Instead, the BBC is sadly succumbing to those who would, again in Nick Griffin's obnoxious words, "defend rights for whites with well-directed boots and fists".
(11) The unspoken rule is that pedestrians and bikes give way to cars even at a zebra crossing – which is obnoxious, not to mention dangerous.
(12) I think that we would make more progress if, instead of complaining about sexualisation – a divisive and nebulous concept – we fought sexism, which is more easily comprehended and is at the root of almost everything troubling and obnoxious.
(13) The only free expression worth anything in a democracy is the right for the person whose views one regards as most obnoxious to be heard.
(14) His personality is obnoxious and he should not be feted as a role model for young people.” The protest will be at the SSE Arena between 5.30pm to 7pm, organisers said.
(15) It seemed particularly obnoxious for him to have used a homophobic slur while starring in a play about the vexed, affectionate and mutually dependent relationship between two men.
(16) Facebook Twitter Pinterest Of course their unspeakably obnoxious stage manner was not to everybody’s taste.
(17) Dunkin' Donuts was cutting hot chocolate, while Starbucks obnoxiously announced it would not bother to comply for months at least.
(18) Snoring is a common obnoxious disturbance in human society.
(19) RMT is in consultation with our taxi members over the possibility of a boycott of this obnoxious and abusive character.” An RMT spokesman said it was a matter for LBC to decide whether to continue to employ Mellor as a presenter, but added: “If he’s supposed to be presenting a balanced debate there’s a question about whether he is a fit person to present the programme.” LBC had no immediate comment.
(20) "There is a lot of energy and it's brilliant to be part of it because I know that back in the day I would have dragged myself through this and been as loud as hell, smoking two cigarettes at once and being really obnoxious.