(1) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(2) The fine structure of neurofibrillary tangles in the hippocampal gyrus, substantia nigra, pontine nuclei and locus coeruleus of the brain was postmortem studied in a case of progressive supranuclear palsy.
(3) Two small populations of GLY + neurons were observed outside of the named nuclei of the SOC; one was located dorsal to the LSO, near its dorsal hilus, and the other was identified near the medial pole of the LSO.
(4) A topographic relationship was recognized between the MM and the anterior thalamic nuclei.
(5) Diplotene spermatocytes have the largest nuclei of all germ cells.
(6) The DNA untwisting enzyme has been purified approximately 300-fold from rat liver nuclei.
(7) DNA in situ is progressively denatured when the cells or nuclei are treated with increasing concentration of acridine orange (AO).
(8) The deep cerebellar nuclei were moderately labeled at birth and gradually decreased in density thereafter.
(9) Mitoses of nuclei of myocytes of the left ventricle of the heart observed in two elderly people who had died of extensive relapsing infarction are described.
(10) The ability of cytoplasmic extracts to induce DNA synthesis in isolated, quiescent nuclei.
(11) In high concentrations of antiserum, some of the agglutinated cells of L. h. hertigi were enlarged and showed syncytial characters that included up to five nuclei, two dividing nuclei and five basal bodies associated with a single kinetoplast.
(12) The responses of adrenocorticotropin (ACTH), renin, epinephrine and norepinephrine and arterial pressure and heart rate (HR) to hypotensive hemorrhage were examined before and 1 h after lesion of the paraventricular nuclei (PVN) in pentobarbital-anesthetized rats and 1 day before and 4 days after lesion of the PVN in conscious rats.
(13) The anatomic and functional development of the suprachiasmatic nuclei (SCN) was studied in the gray short-tailed opossum, Monodelphis domestica.
(14) The rate of nuclei stained by Pr-122 is different from that of Pr-192 in both growing and quiescent cultures.
(15) Using a monoclonal antibody against dopamine and a rabbit antiserum against serotonin, 5-methoxytryptamine or tryptamine, we were able to achieve the simultaneous localization of two amines in glutaraldehyde-fixed sections of rat dorsal raphe nuclei.
(16) The results obtained further knowledge of the anatomy of the nuclei, specifically the areas used for the prosthesis implantation and the underlying tissue.
(17) The phosphorylation pattern was affected by the addition of cholera toxin or GDP beta S to the isolated nuclei.
(18) While the heaviest anterogradely labeled ascending projections were observed to the contralateral ventral posterolateral nucleus of the thalamus, pars oralis (VPLo), efferent projections were also observed to the contralateral ventrolateral thalamic nucleus (VLc) and central lateral (CL) nucleus of the thalamic intralaminar complex, magnocellular (and to a lesser extent parvicellular) red nucleus, nucleus of Darkschewitsch, zona incerta, nucleus of the posterior commissure, lateral intermediate layer and deep layer of the superior colliculus, dorsolateral periaqueductal gray, contralateral nucleus reticularis tegmenti pontis and basilar pontine nuclei (especially dorsal and peduncular), and dorsal (DAO) and medial (MAO) accessory olivary nuclei, ipsilateral lateral (external) cuneate nucleus (LCN) and lateral reticular nucleus (LRN), and to a lesser extent the caudal medial vestibular nucleus (MVN) and caudal nucleus prepositus hypoglossi (NPH), and dorsal medullary raphe.
(19) No HRP-labeled axons were found in the facial and solitary nuclei and the cerebellum.
(20) The reaction of cis-diamminedichloroplatinum(II) with chicken erythrocyte nuclei produces covalent cross-linking of HMG proteins 1, 2 and E to DNA, in addition to cross-links amongst LMG proteins.
Nuclein
Definition:
(n.) A constituent of the nuclei of all cells. It is a colorless amorphous substance, readily soluble in alkaline fluids and especially characterized by its comparatively large content of phosphorus. It also contains nitrogen and sulphur.
Example Sentences:
(1) Endogenous interferon was produced in animals in response to the administration of tobacco mosaic virus (TMV), tilorone and sodium nucleinate.
(2) Immunocorrection of patients with the Fuchs' syndrome was attempted, and analysis of the immunologic status before and after treatment by means of sodium nucleinate immunomodulator and traditional therapy was made.
(3) After sodium nucleinate immunomodulation, ritmilen therapy proved to be beneficial in 46.6% of the patients.
(4) The effects of essential forte have been examined when it was combined with both a tocopherol, and sodium nucleinate.
(5) It was found that the concentration of summary nucleinic acids in the tissues increases under the effect of the drug, the oxidative reactions enzymes become more active, while the activity of non-oxidative reactions enzymes of the pentosophosphate route and of acid and basic endoribonucleases in inhibited.
(6) Experimental findings have shown that behind the stimulating effect of the drug there is the activation of the synthesis of nucleinic acids, the rise of the mitotic activity of the interalveolar membranes cells of the lung remnants.
(7) The side-effect of heat-inactivated vaccine from pathogenic escherichia was reduced in animals inoculated with sodium nucleinate preliminarily.
(8) The heterogeneity of resident peritoneal macrophages and peritoneal macrophages was studied in different periods following oral administration of sodium nucleinate according to their ability to bind and phagocytize sheep erythrocytes opsonized by means of specific rabbit IgG.
(9) The use of sodium nucleinate in combination with polyvinylprrolidone (hemodez) prolonged the tachyphylactic action of sodium nucleinate and increased its effectiveness.
(10) In children with acute glomerulonephritis sodium nucleinate normalized decreased T-suppressor cells and increased IgG and circulating immune complexes (CIC), resulting in a pronounced remission of disease.
(11) The tobaco mozaic virus, tilorone and sodium nucleinate used perorally in treatment of experimental infections of mice caused by the viruses of East and West encephalomyelitis, influenza and tick encephalitis had a pronounced protective effect.
(12) TMV, tilorone and sodium nucleinate given per os exerted a marked protective effect in mice against tick-borne encephalitis, eastern and western equine encephalomyelitis and influenza virus infections.
(13) As revealed in these studies, the kinetics of the growth of the populations of both strains in the exponential phase did not depend on the concentration of sodium nucleinate in the culture medium.
(14) Forty-seven children suffering from insulin-dependent diabetes mellitus were examined for criteria of the efficacy of the immunocorrecting drugs prodigiosan, sodium nucleinate, decaris and splenin.
(15) The wound-healing activity of quinazopyrine was higher than that of methyluracil, dimexide, pentoxyl, sodium nucleinate, potassium orotate and riboxine.
(16) Sodium nucleinate and its mononucleotides have been found capable of stimulating the multiplication and virulence of shigellae, as well as their sensitivity to antibiotics, in cultures grown in nutrient media.
(17) Sodium nucleinate was satisfactorily tolerated by the patients, it induced no adverse reactions and had a favourable effect on the patients immunity.
(18) This compound contains peptides, oligosaccharides and nucleinic acid derivatives, which are supposed to improve transport of glucose and oxygen into cells.
(19) The conclusion is drawn that if indicated clinically, sodium nucleinate of diucifon can be administered in spite of the normal immune status in accordance with the level I tests.
(20) It is shown that sodium nucleinate applied in a complex with the generally accepted nonoperative therapy corrects the immune status of patients with atherosclerosis of the lower limb arteries in stage IIB circulatory disorders.