(n.) The matter composing the nucleus of a cell; the protoplasm of the nucleus; karyoplasma.
Example Sentences:
(1) Depending on the differential sensitivity of nuclear T-ag to extraction by salt and detergent, nuclear T-ag could be separated into nucleoplasmic T-ag, salt-sensitive T-ag and matrix-bound T-ag subclasses.
(2) Hepatocellular thyroid status was estimated from the relative abundances of two nucleoplasmic proteins on polyacrylamide gel electrophoregrams.
(3) The two characteristic forms of eucaryotic DNA-dependent RNA polymerases, polymerase I (nucleolar) and polymerase II (nucleoplasmic), were identified.
(4) The affinity labeling was intensified when resealed vesicles were made leaky by freezing or ultrasonication, suggesting that the poly(A) binding proteins are accessible from the nucleoplasmic but not the cytoplasmic face of the envelope.
(5) Turnover rates of the components of systems for RNA synthesis of rat-liver nucleus, nucleolus, and nucleoplasm were investigated.
(6) These studies support the conclusion that there are no clear differences between many nucleoplasmic and chromatin-bound nonhistone proteins.
(7) Most spheres are free in the nucleoplasm, but a few are attached to chromosomes at specific chromosome loci, the sphere organizers (SOs).
(8) Experiments involving fractionation of cell lysates and indirect immunofluorescence microscopy of control and interferon-treated cells revealed that the 204 protein is nucleolar and nucleoplasmic.
(9) The genes for U1 and U2 snRNAs (small nuclear RNAs) are clustered and present in the nucleoplasmic DNA; however, the localization of U3 snRNA genes is not known.
(10) Changes in the characteristics of the nucleoplasm were examined in young hamster facial motoneurons of 15 and 20 days postnatal age and in the adult (100 days postnatal age) at both the light and electron microscope levels.
(11) Small nucleolus-related bodies which occur in the nucleoplasm of "micronuclei" lacking nucleolar organizers have been studied by immunofluorescence microscopy.
(12) This initial displacement of nuclear material to the cell border may indicate an association between the nucleoplasm and the plasma membrane.
(13) The protein compositions of hnRNP particles found in the nucleoplasm fraction and in the chromatin-nucleolar fraction are very similar.
(14) Absorbance profiles and radioactivity patterns of nucleoplasmic RNA were similar in the two groups of rats.
(15) Fluorescence microscopy further indicated that in both nuclear preparations, the neoglycoprotein binding sites were associated with the nucleoli as well as with nucleoplasmic ribonucleoprotein elements.
(16) After 24 h of cultivation a dramatic increase in RNA synthesis is observed; it is the highest in the heterogeneous nucleoplasmic RNA fraction.
(17) Antibody raised against the 43K antigen reacted with the stichosome and cuticle of the mature larva and the cytoplasm and nucleoplasm, but not nucleolus, of all nuclei of infected host cells (Nurse cells) in sections of infected tissues.
(18) In vitro experiments have shown that p24 is localized within the nucleolus, while p27 expression is probably confined to the nucleoplasm.
(19) Type III was characterized mainly by homogenization of the nucleoplasm and cytoplasm and dilation of the perinuclear cisternae and endoplasmic reticulum, thus showing features of 'non-lysosomal vesiculate' cell death.
(20) In addition to the fraction of Ran protein complexed to RCC1, a 25-fold molar excess of the protein over RCC1 was found in the nucleoplasm of HeLa cells.
Nucleus
Definition:
(n.) A kernel; hence, a central mass or point about which matter is gathered, or to which accretion is made; the central or material portion; -- used both literally and figuratively.
(n.) The body or the head of a comet.
(n.) An incipient ovule of soft cellular tissue.
(n.) A whole seed, as contained within the seed coats.
(n.) A body, usually spheroidal, in a cell or a protozoan, distinguished from the surrounding protoplasm by a difference in refrangibility and in behavior towards chemical reagents. It is more or less protoplasmic, and consists of a clear fluid (achromatin) through which extends a network of fibers (chromatin) in which may be suspended a second rounded body, the nucleolus (see Nucleoplasm). See Cell division, under Division.
(n.) The tip, or earliest part, of a univalve or bivalve shell.
(n.) The central part around which additional growths are added, as of an operculum.
(n.) A visceral mass, containing the stomach and other organs, in Tunicata and some mollusks.
Example Sentences:
(1) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(2) The present results provide no evidence for a clear morphological substrate for electrotonic transmission in the somatic efferent portion of the primate oculomotor nucleus.
(3) In the caudal spinal trigeminal nucleus (Vc), the collaterals of one half of the periodontium afferent fibers terminated mainly in lamina V at the rostral and middle levels of Vc.
(4) It is concluded that in the mouse model the ability of buspirone to reduce the aversive response to a brightly illuminated area may reflect an anxiolytic action, that the dorsal raphe nucleus may be an important locus of action, and that the effects of buspirone may reflect an interaction at 5-hydroxytryptamine receptors.
(5) hypoglossal nucleus), whereas in other areas the angiotensinogen gene was expressed only in a certain population of glial cells.
(6) Local application of 8-OH-DPAT (0-5 micrograms) into the median raphe nucleus, facilitated male rat sexual behavior, as evidenced by a decrease in number of intromissions preceding ejaculation and in time to ejaculation.
(7) In addition, lightly immunostained cells were distinguished in the caudal portion of the hypothalamic arcuate nucleus, area of tuber cinereum, retrochiasmatic area, and rostral portion of the paraventricular thalamic nucleus after colchicine treatment.
(8) Arising of the nucleus from a polyheteronomous nucleoid of proeukaryotes.
(9) It is possible that the IgE that linked abnormally with the propofol had specific binding sites for the phenyl nucleus and the isopropyl groups, which are present in propofol and many other drugs.
(10) We conclude that neuronal activities in the region of the retrofacial nucleus are important both in the integration of stimuli from the central chemoreceptors and in defining the discharge patterns of respiratory neurons.
(11) A 68 year-old man with a history of right thalamic hemorrhage demonstrated radiologically in the pulvinar and posterior portion of the dorsomedian nucleus developed a clinical picture of severe physical sequelae associated with major affective, behavioral and psychic disorders.
(12) While the heaviest anterogradely labeled ascending projections were observed to the contralateral ventral posterolateral nucleus of the thalamus, pars oralis (VPLo), efferent projections were also observed to the contralateral ventrolateral thalamic nucleus (VLc) and central lateral (CL) nucleus of the thalamic intralaminar complex, magnocellular (and to a lesser extent parvicellular) red nucleus, nucleus of Darkschewitsch, zona incerta, nucleus of the posterior commissure, lateral intermediate layer and deep layer of the superior colliculus, dorsolateral periaqueductal gray, contralateral nucleus reticularis tegmenti pontis and basilar pontine nuclei (especially dorsal and peduncular), and dorsal (DAO) and medial (MAO) accessory olivary nuclei, ipsilateral lateral (external) cuneate nucleus (LCN) and lateral reticular nucleus (LRN), and to a lesser extent the caudal medial vestibular nucleus (MVN) and caudal nucleus prepositus hypoglossi (NPH), and dorsal medullary raphe.
(13) In contrast to this, adrenalectomy decreased ANP levels markedly in the organum vasculosum laminae terminalis and preoptic periventricular nucleus, which are reportedly involved in the central regulation of salt and water homeostasis.
(14) The shape of the nucleus changes from ovoid to a distinctive, radially splayed lobulated structure.
(15) Immunocytochemical analysis also suggested that bFGF immunoreactivity was present in the nucleus as well as the cytoplasm of astrocytes and CA2 neurons.
(16) The effect of Y-516 on the hyperactivity induced by dopamine injected bilaterally into the nucleus accumbens was compared with those of clocapramine (CCP), haloperidol (HPD) and chlorpromazine (CPZ).
(17) Moderately differentiated tumor revealed a wider range of nucleus size, less clustering (coefficient--3.59) and more hyperchromatic (70.1%) and "bare" (49.4%) nuclei and large nucleoli (22.2%).
(18) The majority of intensively stained and densely packed cells have been observed in tv nucleus.
(19) Following electrical stimulation of the hypothalamic paraventricular nucleus (PVN) area, 21% of the neurons were orthodromically excited, 6% were inhibited and 2.5% were antidromically activated.
(20) Proenkephalin A-related immunoreactive neuronal perikarya were detected in the central gray, reticular formation, nucleus raphes, trapezoid body, nucleus parabrachialis lateralis and medialis, nucleus spinalis nervi trigemini, nucleus dorsalis nervi vagi, and in the nucleus tractus solitarii.