(a.) Binding in law or conscience; imposing duty or obligation; requiring performance or forbearance of some act; -- often followed by on or upon; as, obedience is obligatory on a soldier.
Example Sentences:
(1) It is important to note that the proposed mechanism is not obligatory for androgen or other steroid hormone action.
(2) However, besides these obligatory alterations a high inter- and intraindividual variability of structural aspects is found in MS lesions.
(3) The presence of the other islet cell-types may be obligatory for these appropriate responses.
(4) From the derived cell flux in these compartments we suggest that 1) many more pre-B cells are produced than needed by the peripheral B cell pool; 2) if TdT is an obligatory stage in B cell genesis, there must be at least two cell cycles in the pre-B cell compartment; 3) if it is not, the TdT+ stage may be bypassed, with HIS24+TdT-Ig- cells perhaps feeding directly into the pre-B cell compartment.
(5) Neither cytochrome a nor cytochrome c appears to be an obligatory intermediate in cyanide-sensitive nicotinamide adenine dinucleotide oxidation in B. subtilis.
(6) Thus, the results of this study indicate that retinal is an obligatory intermediate in the hepatic production of retinoic acid from retinol and that cytosolic and microsomal retinol dehydrogenases play a key role in this process.
(7) Thus, even though LPS is a potent inducer of IFN-beta in murine macrophages, class I IFN expression may not be an obligatory intermediate event in the LPS-driven activation of ISRE binding activity.
(8) The four hosts (Mollusc -- Crustacean -- Odonat -- Amphibian) are obligatory in the life cycle for it is impossible to infect the Insects directly with the cecariae or the frog (tadpoles as well as adults) with the mesocercariae.
(9) The synergistic actions of E2 and either AA, the obligatory precursor of PGF2 alpha, or A23187, an enhancer of AA release from phospholipid stores, point to a stimulatory effect of E2 on prostaglandin synthase activity.
(10) No wt-1 expression was detected at any stage of tooth development showing that wt-1 is not obligatory for regulation of Egr-1 expression.
(11) These findings show that class switch by deletion of DNA regions in mature plasma cells is not obligatory for the secretion of immunoglobulin classes other than IgM.
(12) Serotonin plays an obligatory role in the initiation and expression of leech feeding behavior by its differential modulation of central neuronal networks and peripheral glands and muscles.
(13) However, in spite of these similarities, they differentially stimulate estrogenic responses that were previously thought to be interrelated and obligatory for full estrogenic action.
(14) These results, together with data from the native proteins, are consistent with obligatory 1-electron transfer between dehydrogenase and ETF possibly involving the exposed dimethylbenzene edge of ETF.
(15) Although Mg2+ is absolutely required for activation of adenylate cyclase by the GTP analogue guanosine 5'-[beta gamma-imido]triphosphate (p[NH]ppG), it is not obligatory for p[NH]ppG-stimulated ADP-ribosylation by cholera toxin.
(16) This suggests that normally the midline floor plate cells do provide guidance cues, but that these cues are not obligatory.
(17) The protein supply recommended for a certain age group should not be obligatory for the individual child.
(18) The results strongly suggest that the obligatory antigen processing event required for helper T cell recognition of alloantigen is simply the insertion of the alloantigen into the same membrane bilayer as the syngeneic Ia restricting element.
(19) This new function is derived by assuming that all chromosome arms except the short arms of acrocentric chromosomes hav an obligatory chiasma, and that the remaining chiasmata are distributed at random; assumptions which may correspond reasonably well to reality.
(20) Its somewhat unique features have attracted widespread interest both nationally and internationally and may be seen as part of an international movement towards obligatory CME in Western Medicine.
Quarantine
Definition:
(n.) A space of forty days; -- used of Lent.
(n.) Specifically, the term, originally of forty days, during which a ship arriving in port, and suspected of being infected a malignant contagious disease, is obliged to forbear all intercourse with the shore; hence, such restraint or inhibition of intercourse; also, the place where infected or prohibited vessels are stationed.
(n.) The period of forty days during which the widow had the privilege of remaining in the mansion house of which her husband died seized.
(v. t.) To compel to remain at a distance, or in a given place, without intercourse, when suspected of having contagious disease; to put under, or in, quarantine.
Example Sentences:
(1) Policies recommending quarantine, isolation, mandatory testing of certain populations, and vigorous public education are explored.
(2) Control measures against the disease include quarantine restrictions and prevention by means of specific preparations of active and passive effect.
(3) Huge blocks of frozen meat at a cold store in Northern Ireland, Freeza Foods, which had been quarantined by officials suspicious of its labelling and state of packaging, were found to contain 80% horse.
(4) More than 40 people known to have come into contact with her have been quarantined.
(5) Quarantines appeared to be effective in restricting the VEE virus activity to south Texas.
(6) A one month quarantine period for incoming stock was established, and only gI-seronegative pigs were admitted to the herd.
(7) They also confirmed there was no guarantee that the fund will not supplant existing National Health and Medical Research Council funding – which is not quarantined.
(8) Barbara Shaw, the Alice Springs-based anti-Intervention campaigner, speaks of how welfare quarantining particularly rankles with Indigenous people who remembered the not-so-distant past: “There are a lot of people out there who, when they were young fellas, they only got paid rations.
(9) Pham’s dog, held in quarantine in Dallas, has also tested negative for Ebola .
(10) Pertinent themes in the history of responses to epidemic disease in the United States in the past two hundred years include an initial underestimation of the severity of the epidemic; the prevalence of fear and anxiety; flight, denial, and scape-goating as a result of fear; efforts to quarantine and isolate carriers and the sick; the assertion of rational policies by coalitions of business, government, and medical leaders; the recruitment of a special cadre of physicians to treat the sick; the similarity of responses to both epidemic and endemic infectious diseases; and the high cost of epidemics, which is shared by government, philanthropy, and private individuals.
(11) It provides a measure of relief and reassurance.” Five of the students who had been under quarantine or monitoring returned to school on Monday, and the remaining students will be back in school by Tuesday, Dallas Independent School District superintendent Mike Miles said Monday.
(12) He was unable to embrace her because of the quarantine restrictions.
(13) Conventional approaches to public health stemming from epidemics of the 19th century included mandatory screening, isolation, quarantine, contact tracing, and breaking patient confidentiality.
(14) In Brisbane during October 1988 one larva of the exotic dengue vector Aedes albopictus (Skuse) was collected by quarantine officers from a consignment of used vehicle tyres imported from Asia.
(15) Can we help my dad to come?’ And they fixed his papers to come to this country,” said Duncan’s brother Wilfred Smallwood, whose son, Oliver Smallwood, remains in quarantine with the rest of the household that hosted Duncan before he was diagnosed with Ebola .
(16) It was recommended to extend the quarantine areas as well as the radius of ring vaccination and to prolong the period of quarantine.
(17) We recommend that virus detection software be installed on personal computers where the interchange of diskettes among computers is necessary, that write-protect tabs be placed on all program master diskettes and data diskettes where data are being read and not written, that in the event of a computer virus outbreak, all available diskettes be quarantined and scanned by virus detection software, and to facilitate quarantine and scanning in an outbreak, that diskettes be stored in organized files.
(18) Immediately after beginning to feel ill and discovering he was running a slight fever, the cameraman quarantined himself and sought medical advice.
(19) The rarity of Marburg and Ebola virus transmission, decreasing use of imported African monkeys, and quarantine efforts have presumably been responsible for the lack of additional episodes until 1989, when a new filovirus related to Ebola was isolated from quarantined monkeys in Reston, Virginia.
(20) The system of monitoring, quarantine and isolation was established to protect those who cared for Mr Duncan as well as the community at large by identifying any potential ebola cases as early as possible and getting those individuals into treatment immediately.” Duncan travelled from Liberia to the US on 19 September to join his girlfriend, Louise Troh, the mother of his son, Karsiah.