(a.) Binding in law or conscience; imposing duty or obligation; requiring performance or forbearance of some act; -- often followed by on or upon; as, obedience is obligatory on a soldier.
Example Sentences:
(1) It is important to note that the proposed mechanism is not obligatory for androgen or other steroid hormone action.
(2) However, besides these obligatory alterations a high inter- and intraindividual variability of structural aspects is found in MS lesions.
(3) The presence of the other islet cell-types may be obligatory for these appropriate responses.
(4) From the derived cell flux in these compartments we suggest that 1) many more pre-B cells are produced than needed by the peripheral B cell pool; 2) if TdT is an obligatory stage in B cell genesis, there must be at least two cell cycles in the pre-B cell compartment; 3) if it is not, the TdT+ stage may be bypassed, with HIS24+TdT-Ig- cells perhaps feeding directly into the pre-B cell compartment.
(5) Neither cytochrome a nor cytochrome c appears to be an obligatory intermediate in cyanide-sensitive nicotinamide adenine dinucleotide oxidation in B. subtilis.
(6) Thus, the results of this study indicate that retinal is an obligatory intermediate in the hepatic production of retinoic acid from retinol and that cytosolic and microsomal retinol dehydrogenases play a key role in this process.
(7) Thus, even though LPS is a potent inducer of IFN-beta in murine macrophages, class I IFN expression may not be an obligatory intermediate event in the LPS-driven activation of ISRE binding activity.
(8) The four hosts (Mollusc -- Crustacean -- Odonat -- Amphibian) are obligatory in the life cycle for it is impossible to infect the Insects directly with the cecariae or the frog (tadpoles as well as adults) with the mesocercariae.
(9) The synergistic actions of E2 and either AA, the obligatory precursor of PGF2 alpha, or A23187, an enhancer of AA release from phospholipid stores, point to a stimulatory effect of E2 on prostaglandin synthase activity.
(10) No wt-1 expression was detected at any stage of tooth development showing that wt-1 is not obligatory for regulation of Egr-1 expression.
(11) These findings show that class switch by deletion of DNA regions in mature plasma cells is not obligatory for the secretion of immunoglobulin classes other than IgM.
(12) Serotonin plays an obligatory role in the initiation and expression of leech feeding behavior by its differential modulation of central neuronal networks and peripheral glands and muscles.
(13) However, in spite of these similarities, they differentially stimulate estrogenic responses that were previously thought to be interrelated and obligatory for full estrogenic action.
(14) These results, together with data from the native proteins, are consistent with obligatory 1-electron transfer between dehydrogenase and ETF possibly involving the exposed dimethylbenzene edge of ETF.
(15) Although Mg2+ is absolutely required for activation of adenylate cyclase by the GTP analogue guanosine 5'-[beta gamma-imido]triphosphate (p[NH]ppG), it is not obligatory for p[NH]ppG-stimulated ADP-ribosylation by cholera toxin.
(16) This suggests that normally the midline floor plate cells do provide guidance cues, but that these cues are not obligatory.
(17) The protein supply recommended for a certain age group should not be obligatory for the individual child.
(18) The results strongly suggest that the obligatory antigen processing event required for helper T cell recognition of alloantigen is simply the insertion of the alloantigen into the same membrane bilayer as the syngeneic Ia restricting element.
(19) This new function is derived by assuming that all chromosome arms except the short arms of acrocentric chromosomes hav an obligatory chiasma, and that the remaining chiasmata are distributed at random; assumptions which may correspond reasonably well to reality.
(20) Its somewhat unique features have attracted widespread interest both nationally and internationally and may be seen as part of an international movement towards obligatory CME in Western Medicine.
Voluntary
Definition:
(v. t.) Proceeding from the will; produced in or by an act of choice.
(v. t.) Unconstrained by the interference of another; unimpelled by the influence of another; not prompted or persuaded by another; done of his or its own accord; spontaneous; acting of one's self, or of itself; free.
(v. t.) Done by design or intention; intentional; purposed; intended; not accidental; as, if a man kills another by lopping a tree, it is not voluntary manslaughter.
(v. t.) Of or pertaining to the will; subject to, or regulated by, the will; as, the voluntary motions of an animal, such as the movements of the leg or arm (in distinction from involuntary motions, such as the movements of the heart); the voluntary muscle fibers, which are the agents in voluntary motion.
(v. t.) Endowed with the power of willing; as, man is a voluntary agent.
(v. t.) Free; without compulsion; according to the will, consent, or agreement, of a party; without consideration; gratuitous; without valuable consideration.
(v. t.) Of or pertaining to voluntaryism; as, a voluntary church, in distinction from an established or state church.
(n.) One who engages in any affair of his own free will; a volunteer.
(n.) A piece played by a musician, often extemporarily, according to his fancy; specifically, an organ solo played before, during, or after divine service.
(n.) One who advocates voluntaryism.
Example Sentences:
(1) "Especially at a time when they are turning down voluntary requests and securing the positions of senior managers."
(2) Voluntary intake and nutritive value of diets selected by goats grazing a shrubland at Marin county, N.L., Mexico were determined.
(3) During ischaemia M1 stretch responses showed a more rapid and pronounced decline than did M2 responses and were abolished before voluntary power was appreciably affected.
(4) Decreased maximal voluntary squeeze pressures were less severe in continent patients with multiple sclerosis than in incontinent patients with multiple sclerosis.
(5) He got away with a lesser charge of voluntary manslaughter and served five years.
(6) Speaking at The Carbon Show in London today, Philippe Chauvancy, director at climate exchange BlueNext, said that the announcement last week that it is to develop China's first standard for voluntary emission reduction projects alongside the government-backed China Beijing Environmental Exchange, could lay the foundations for a voluntary cap-and-trade scheme.
(7) Surface EMGs at rest and at voluntary eyelid opening after eyelid closing were investigated.
(8) Voluntary entropion, which has been reported only once before, was photographically documented in a 12-year-old girl.
(9) Criteria for evaluating the data were scanning pattern (voluntary preferred reading direction) and reading performance.
(10) The atrophies of motor cortex seemed to be responsible for the disorder of voluntary movement.
(11) The Coalition has also been warned about the costs of voluntary grants schemes.
(12) Lloyds said it would achieve many of the job cuts through making less use of contractors and voluntary severance but admitted that some compulsory redundancies may be inevitable.
(13) But there is one hitch: the four-storey building in Hammersmith is already home to more than 20 voluntary groups working with refugees, the homeless, former young offenders and a range of ethnic minorities including Kurds, Iranians and Iraqis – and they will have to move.
(14) The "size principle" is known to dictate the sequence of recruitment of motor neurons during voluntary or reflex activation of muscles.
(15) It is suggested that contracting extrafusal muscle fibres can modulate the discharge pattern of spindle endings and contribute to the variability of discharge during a voluntary contraction.
(16) In erect subjects, voluntary changes of shape at FRC did not change regional volume distribution.
(17) The centrally generated ;effort' or direct voluntary command to motoneurones required to lift a weight was studied using a simple weight-matching task when the muscles lifting a reference weight were weakened.
(18) Both the extensor indicis and the abductor pollicis longus are functional synergists and are under voluntary control of the brain.
(19) So far there have been 50 voluntary redundancies from editorial and a further 82 commercial jobs have been cut.
(20) fbi justified homicide chart Academics and specialists have long been aware of flaws in the FBI numbers, which are based on voluntary submissions by local law enforcement agencies of paperwork known as supplementary homicide reports.