(a.) Pertinaciously adhering to an opinion, purpose, or course; persistent; not yielding to reason, arguments, or other means; stubborn; pertinacious; -- usually implying unreasonableness.
(a.) Not yielding; not easily subdued or removed; as, obstinate fever; obstinate obstructions.
Example Sentences:
(1) The patient was a forty-five-year-old female who had been troubled by obstinate Raynaud's phenomenon for ten years before the definite diagnosis of pulmonary hypertension was made.
(2) The whole proves his introversion, ambivalence, hypersensitivity, obstinancy, anxieties, behavioral anomalies, a life rich in fantasies and his underestimation of his own literary work.
(3) Soon my piano lessons had turned into me, an obstinate 11-year old, demanding that my neighbour teach me ever-more intricate DOS commands.
(4) Peritoneal pseudomyxoma has several main features: it is insidious, recurrent, obstinate and severe.
(5) Adamant avoidance of division of primary clinical responsibility among cooperating specialists and clinician obstinancy when dealing with third parties can help prevent suicides.
(6) When an obstinate irritable colon is present, a diagnostics of neuroses is indicated.
(7) Twenty-two cases 23 eyes with obstinate stromal keratitis treated by combination of traditional Chinese and Western medicines are reported in this paper.
(8) Scores of people, including comedian Mark Thomas and wilderness hiker Cameron McNeish, have become joint owners of an acre of land previously owned by Michael Forbes, the quarryman and salmon netsman who has become Trump's most famous and obstinate opponent.
(9) The results show the possibility that recombinant human interleukin-1 alpha could be of help for treating obstinate infections not successfully treated with antimicrobial agents alone.
(10) "[The officials] have become obstinate – they are seeking just different ways to mistreat my mother and us as her children," he said.
(11) During the first weeks of the rheumatoid arthritis the following symptoms are found: articular syndromes, more frequently in form of obstinate polyarthralgias, mono-oligoarthritis, accompanied by morning rigidity and accelerated BSR as well as impairment of the general condition.
(12) In a study for the recognition of the urodynamics of the detrusor after administration of the anticholinergic drug Mictonorm 14 patients with obstinate urge symptoms were examined.
(13) But these factors become important when patients, particularly debilitated patients, are infected acutely or chronically with some of the more obstinate bacteria.
(14) Back by the obstinately uninflated elephant, Simon Vose clambered in to his van and set off on another callout for his house maintenance business.
(15) These results show the possibility that KW-2228 could be of use in treating obstinate infections not successfully treated with an antimicrobial agent alone.
(16) Instead, the focus has been on the objective question: could an obstinate and prejudiced person have honestly based the comment made by the defendant on the facts on which the defendant commented?
(17) But with a very strong El Niño driving record global temperatures and a huge patch of hot water, known as “the Blob” , hanging obstinately in the north-western Pacific, things look far worse again for 2016.
(18) Such querulous, opinionated persons are obstinate "bellyachers" who "stick to their guns" and imaginary legal positions to the extent of being a general nuisance.
(19) Three years later, he provoked intense controversy with the publication of Haig: The Educated Soldier, which was sharply at odds with the popular view that the first world war had been the supreme example of "mud, blood and futility", with British generals depicted as callous, obstinate and incompetent.
(20) The knowledge of these diseases is a prerequisite to the causal and lasting treatment of patients affected by the obstinate and occasionally even painful symptom of the burning tongue.
Recalcitrant
Definition:
(a.) Kicking back; recalcitrating; hence, showing repugnance or opposition; refractory.
Example Sentences:
(1) Based on the principles of adaptational mutations and genetic exchange of catabolic activities, it becomes possible to select and engineer microorganisms that are suitable for the degradation of recalcitrant compounds.
(2) A prospective, randomized, double-blind, placebo-controlled multicentre study assessed the clinical efficacy and safety of pulsed electromagnetic limb ulcer therapy (PELUT) in the healing of recalcitrant, predominantly venous leg ulcers.
(3) We present a patient whose genital warts were recalcitrant to treatment.
(4) Isotretinoin (Accutane Capsules) is a synthetic vitamin A compound used for treatment of recalcitrant cystic acne.
(5) Such gene cassettes or operons can be transferred into suitable microbial hosts for extending and custom designing the pathways for rapid degradation of recalcitrant compounds.
(6) Of the 30 patients with warts, most of which were recalcitrant, 14 were cured and the remaining 16 showed marked improvement.
(7) This procedure is a simple and effective method for safe office treatment of patients with recalcitrant recurrent erosion.
(8) The thermal cycle sequencing procedures are advantageous because they allow fast and simple semiautomation of the sequencing reaction; make possible the direct DNA sequencing of PCR products, bacterial colonies and phage plaques; require only femtomoles of template DNA; eliminate the requirement of an independent primer annealing step; remove the requirement of denatured plasmids for sequencing double-stranded templates; and use a highly thermostable DNA polymerase for sequencing through potential recalcitrant secondary structure domains and large linear double-stranded DNA templates such as lambda derivatives.
(9) To study the human teratogenicity of this agent, we investigated 154 human pregnancies with fetal exposure to isotretinoin, a retinoid prescribed for severe recalcitrant cystic acne.
(10) The biosynthesis of prostaglandins (PG) in biopsies from 9 patients with recalcitrant psoriasis was studied before, during, and after treatment with 8-methoxy-psoralen and long-wave ultraviolet light (UVA).
(11) The Dec+ mutants had also acquired the capacity to metabolize other recalcitrant branched hydrocarbons such as 3,6-dimethyloctane and 2,6-dimethyldecane.
(12) Levamisole should be tried in recalcitrant chronic candidoses and bacterial infections not responding to specific antibiotic treatment.
(13) Thus, combination therapy is recommended for treatment of recalcitrant cases of bacterial endocarditis caused by N. mucosa.
(14) If the holding phase is sufficiently prolonged, a reduction in the number and complexity of operative procedures needed for recurrent and recalcitrant cases can be expected.
(15) Treatment of associated systemic disorders may improve the ulcers, but lesions may be recalcitrant and persist for months to years.
(16) Cyclosporine, an immunosuppressive drug, is effective in the treatment of recalcitrant psoriasis.
(17) In recalcitrant cases, however, entrapment of the first branch lateral plantar nerve should be suspected.
(18) These autonomous movements were otherwise recalcitrant to therapy and were felt to arise from neural generators intrinsic to the spinal cord.
(19) The effectiveness and tolerance of isotretinoin have been assessed in 72 cases (34 male and 38 female) suffering from papulo-pustular acne with nodulo-cystic component recalcitrant to traditional treatments.
(20) The government’s strategy is clearly based on a deep confidence that it has time, that it won’t be forced back to the polls by a recalcitrant Senate, that it will have years to reach a rapprochement with the angry states and that it will bring down two more budgets before it has to face the voters.