(superl.) Not young; advanced far in years or life; having lived till toward the end of the ordinary term of living; as, an old man; an old age; an old horse; an old tree.
(superl.) Not new or fresh; not recently made or produced; having existed for a long time; as, old wine; an old friendship.
(superl.) Formerly existing; ancient; not modern; preceding; original; as, an old law; an old custom; an old promise.
(superl.) Continued in life; advanced in the course of existence; having (a certain) length of existence; -- designating the age of a person or thing; as, an infant a few hours old; a cathedral centuries old.
(superl.) Long practiced; hence, skilled; experienced; cunning; as, an old offender; old in vice.
(superl.) Long cultivated; as, an old farm; old land, as opposed to new land, that is, to land lately cleared.
(superl.) Worn out; weakened or exhausted by use; past usefulness; as, old shoes; old clothes.
(superl.) More than enough; abundant.
(superl.) Aged; antiquated; hence, wanting in the mental vigor or other qualities belonging to youth; -- used disparagingly as a term of reproach.
(superl.) Old-fashioned; wonted; customary; as of old; as, the good old times; hence, colloquially, gay; jolly.
(superl.) Used colloquially as a term of cordiality and familiarity.
Example Sentences:
(1) A 2.5-month-old child with cyanotic heart disease who required long-term PGE1 infusions; developed widespread periosteal reactions during the course of therapy.
(2) Yet the Tory promise of fiscal rectitude prevailed in England Alexander had been in charge of Labour’s election strategy, but he could not strategise a victory over a 20-year-old Scottish nationalist who has not yet taken her finals.
(3) A 61-year-old man experienced four bouts of pancreatitis in 1 year.
(4) A total of 104 evaluable patients 20-90 years old treated by direct vision internal urethrotomy a.m. Sachse for urethral strictures reported retrospectively via a questionnaire their sexual potency before and after internal urethrotomy.
(5) A 66-year-old woman with acute idiopathic polyneuritis (Landry-Guillain-Barré [LGB] syndrome) had normal extraocular movements, but her pupils did not react to light or accommodation.
(6) Scatchard analyses of binding data obtained with synaptosomal preparations from 17-day-old embryos revealed two T3 binding sites.
(7) A remarkable deterioration of prognosis with increasing age rises the question whether treatment with cytotoxic drugs should be tried in patients more than 60 years old.
(8) A specimen of a very early ovum, 4 to 6 days old, shown in the luminal form of imbedding before any hemorrhage has taken place, confirms that the luminal form of imbedding does occur.
(9) Data collection at the old hospital for comparison, however, was not always reliable.
(10) A leg ulcer in a 52-year-old renal transplant patient yielded foamy histiocytes containing acid-fast bacilli subsequently identified as a Runyon group III Mycobacterium.
(11) The 36-year-old teacher at an inner-city London primary school earns £40,000 a year and contributes £216 a month to her pension.
(12) Eight-week-old virgin untreated female mice were induced to ovulate using equine chorionic gonadotropin (eCG) and human chorionic gonadotropin (hCG), and were then caged with males overnight.
(13) The authors report an ocular luxation of a four-year-old girl after a bicycle accident.
(14) Peak incidence is found among 40 to 49-year-old and 60 to 64-year-old women.
(15) The capillary-adipocyte distances were shorter and the vascularization density was higher in old rats.
(16) Brilliant, old-fashioned speech, from the days before teleprompters became all-dominant.
(17) Though the 54-year-old designer made brief returns to the limelight after his fall from grace, designing a one-off collection for Oscar de la Renta last year , his appointment at Margiela marks a more permanent comeback.
(18) He also deals with the incidence, conservative and surgical treatment of osteo-arthrosis in old age and with the possibilities of its prevention.
(19) Sterile, pruritic papules and papulopustules that formed annular rings developed on the back of a 58-year-old woman.
(20) The first patient, an 82-year-old woman, developed a WPW syndrome suggesting posterior right ventricular preexcitation, a pattern which persisted for four months until her death.
Used
Definition:
(imp. & p. p.) of Use
Example Sentences:
(1) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
(2) These variants may serve as useful gene markers in alcohol research involving animal model studies with inbred strains in mice.
(3) Therefore, these findings may extend the use of platelets as neuronal models.
(4) All transplants were performed using standard techniques, the operation for the two groups differing only as described above.
(5) The resulting dose distribution is displayed using traditional 2-dimensional displays or as an isodose surface composited with underlying anatomy and the target volume.
(6) It was tested for recovery and separation from other selenium moieties present in urine using both in vivo-labeled rat urine and human urine spiked with unlabeled TMSe.
(7) A study revealed that the percentage of active sperm in semen 30 seconds after ejaculation was 10.3% when a nonoxynol 9 latex condom was used as opposed to 55.9% in a nonspermicidal condom.
(8) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(9) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(10) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
(11) Spectral analysis of spontaneous heart rate fluctuations, a powerful noninvasive tool for quantifying autonomic nervous system activity, was assessed in Xenopus Laevis, intact or spinalized, at different temperatures and by use of pharmacological tools.
(12) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(13) Questionnaires were used and the respondent self-designation method measured leadership.
(14) At 36 h postsurgery, RBCs were examined by 23Na-NMR by using dysprosium tripolyphosphate as a chemical shift reagent.
(15) Biochemical, immunocytochemical and histochemical methods were used to study the effect of chronic acetazolamide treatment on carbonic anhydrase (CA) isoenzymes in the rat kidney.
(16) Use of the improved operative technique contributed to reduction in number of complications.
(17) Down and up regulation by peptides may be useful for treatment of cough and prevention of aspiration pneumonia.
(18) Our data suggest that a rational use of surveillance cultures and serological tests may aid in an earlier diagnosis of FI in BMT patients.
(19) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(20) Models able to describe the events of cellular growth and division and the dynamics of cell populations are useful for the understanding of functional control mechanisms and for the theoretical support for automated analysis of flow cytometric data and of cell volume distributions.