(1) The structure of (+)-nortrachelogenin was established as 8(R), 8'(R)-4,4',8'-trihydroxy-3,3'-dimethoxylignan-olid(9, 9') on the basis of spectroscopic evidence and comparison with its enantiomer, (-)-nortrachelogenin.
(2) A fourteen-membered lactone, (R)-(Z,E)-9,11-octadecadien-13-olide, was isolated from extruded abdominal glands of a Neotropical, nymphalid butterfly.
(3) 2-Buten-4-olide, which inhibits vagus nerve activity via the central nervous system, prevented the 2-DG increased [3H] choline uptake and subsequent [3H] ACh synthesis as well as the increase in gastric acid secretion.
(4) Ludartin [3], 8-angeloyloxy-3-hydroxyguaia-3(15),10(14),11(13)-trien-6,12- olide [4], hymenin [5], mexicanin I [6], helenanin [7], and 9-O-desacetylsparthulin-2-O-angelate [8] were found to exhibit protection.
(5) The sugar acids, 3,4-dihydroxybutanoic acid gamma-lactone, 2-buten-4-olide and 2,4,5-trihydroxy pentanoic acid gamma-lactone which were found in blood modulate feeding behavior of rats by modifying neuronal activity in the lateral hypothalamic area [LHA] and the ventromedial hypothalamic nucleus [VMH].
(6) On the other hand, acetylation at high temperature of the 4,6-O-benzylidene derivative of 1 (11) gave the 2,3-unsaturated, six-membered lactone (12), precursor of 2-acetamido-6-acetoxyhexa-2,4-dien-5-olide (14).
(7) macrolactones 12-keto-9(Z)-octadecen-11-olide and 12-keto-9(Z)-octadecen-13-olide.
(8) The involvement of a feeding-related endogenous sugar acid, 2-buten-4-olide (2-B4O) on central regulation of gastric acid secretion, and its antiulcer effects on several gastric and duodenal experimental ulcer models were investigated in rats.
(9) alpha-terpineol, 2-n-heptylpyridine, m-cresol and (A)-6-dodecen-4-olide and the investigation of the stereochemistry of the double bond in (Z)-6-dodecen-4-olide by means of iterative computer analysis are described.
(10) The dehalogenation step in the chlorophenol degradation is the cycloisomerization of the cis,cis-chloromuconic acid to 4-carboxymethylenebut-2-en-4-olide in the ortho fission pathway.
(11) 2-Buten-4-olide (2-B-4-O) has been identified in the serum of fasted rats and proved to act as a feeding suppressant.
(12) 4-Carboxymethyl-4-methylbut-2-en-4-olide (4-methyl-2-enelactone) isomerase, transforming 4-methyl-2-enelactone to 3-methyl-2-enelactone, was purified from a derivative strain of Pseudomonas sp.
(13) In an aqueous extract of fruit bodies of Coprinus comatus 3-octanone, 3-octanol, 1-octen-3-ol, 1-octanol, 2-methyl-2-penten-4-olide, 1-dodecanol and caprylic acid were identified conclusively and n-butyric and isobutyric acids preliminarily.
(14) 3-Octanol, 1-octen-3-ol, 1-octanol and 2-methyl-2-penten-4-olide were the volatiles with the strongest flavour.
(15) The bioassays also led to the previously known related diterpenes, kolavenic acid (2) which has not been reported as a constituent of this plant, and 16 alpha-hydroxy-cleroda-3,13(14)Z-dien-15,16-olide (1) which is previously known to be in this plant.
(16) 4-Phenyl-2,3-dihydroxy-2-buten-4-olide (PDHB) and 4-phenyl-2,3-dioxo-4-butenolide (PDOB) accelerated LA peroxidation in 10% EtOH.
(17) 1H-Indolo[3',2':4,5]pyrido[3,2-b]-2-penten-5-olide (6) and 1H,5H-indolo[3',2'-c]-6,7-dihydro-2-pyridone (7), rigid analogues of methyl 4-ethyl-beta-carboline-3-carboxylate (8) and N-methyl-4-ethyl-beta-carboline-3-carboxamide (9), respectively, were synthesized and their in vitro binding affinities to the central type benzodiazepine receptors were compared.
(18) Select compounds were found to be active at concentrations lower than 5 X 10(-5) M. In particular, the compound 2 alpha-bromo-3 beta-hydroxy-6 beta H-eudesm-11-en-6,13-olide exhibits an extremely low ID50 value at 0.33 X 10(-6) M. Some relationships between chemical structure and cytotoxic activity are suggested, i.e.
(19) Reaction of 1 with hot acetic anhydride-sodium acetate gave a approximately 1:2 mixture of (E)- and (Z)-2-acetamido-6-acetoxyhexa-2,4-dien-4-olide (6-E and 6-Z).
(20) Estrous cycling female Wistar rats were treated ip with 2-buten-4-olide (0, 30 or 100 mg.kg-1.day-1) for 2 weeks.
Olio
Definition:
(n.) A dish of stewed meat of different kinds.
(n.) A mixture; a medley.
(n.) A collection of miscellaneous pieces.
Example Sentences:
(1) These results demonstrated that gC carries O-glycosidically linked oligosaccharides in addition to the N-linked di- and triantennary glycans previously described (F. Serafini-Cessi, F. Dall'Olio, L. Pereira, and G. Campadelli-Fiume, J. Virol.
(2) The other spiders to be reported as causing bites were Hadronyche adelaidensis, Misgolas andrewsi, Aganippe subtristis, Olios calligaster, Isopeda pessleri, Eriophora sp., Phonognatha graeffei, Holoplatys sp., Breda jovialis, Opisthoncus sp., Lycosa sp.
(3) There are too many programmes both on radio and television featuring men shouting at one another ( Today , Newsnight ), and far too few voices and faces belonging to women over the age of 45 (and sticking Edwina Currie, Lulu, Nancy Dell'Olio and Anita Dobson on Strictly feels like the worst kind of sop to me).
(4) Must one take Nancy Dell'Olio as one's fashion icon, or must one tug one's V-neck down to one's belly button and bellow: "Hey!
(5) A beta 1,4-N-acetylgalactosaminyltransferase very similar to that previously described in urine of Sd(a+) individuals (F. Serafini-Cessi, N. Malagolini, and F. Dall'Olio.