(1) The structure of (+)-nortrachelogenin was established as 8(R), 8'(R)-4,4',8'-trihydroxy-3,3'-dimethoxylignan-olid(9, 9') on the basis of spectroscopic evidence and comparison with its enantiomer, (-)-nortrachelogenin.
(2) A fourteen-membered lactone, (R)-(Z,E)-9,11-octadecadien-13-olide, was isolated from extruded abdominal glands of a Neotropical, nymphalid butterfly.
(3) 2-Buten-4-olide, which inhibits vagus nerve activity via the central nervous system, prevented the 2-DG increased [3H] choline uptake and subsequent [3H] ACh synthesis as well as the increase in gastric acid secretion.
(4) Ludartin [3], 8-angeloyloxy-3-hydroxyguaia-3(15),10(14),11(13)-trien-6,12- olide [4], hymenin [5], mexicanin I [6], helenanin [7], and 9-O-desacetylsparthulin-2-O-angelate [8] were found to exhibit protection.
(5) The sugar acids, 3,4-dihydroxybutanoic acid gamma-lactone, 2-buten-4-olide and 2,4,5-trihydroxy pentanoic acid gamma-lactone which were found in blood modulate feeding behavior of rats by modifying neuronal activity in the lateral hypothalamic area [LHA] and the ventromedial hypothalamic nucleus [VMH].
(6) On the other hand, acetylation at high temperature of the 4,6-O-benzylidene derivative of 1 (11) gave the 2,3-unsaturated, six-membered lactone (12), precursor of 2-acetamido-6-acetoxyhexa-2,4-dien-5-olide (14).
(7) macrolactones 12-keto-9(Z)-octadecen-11-olide and 12-keto-9(Z)-octadecen-13-olide.
(8) The involvement of a feeding-related endogenous sugar acid, 2-buten-4-olide (2-B4O) on central regulation of gastric acid secretion, and its antiulcer effects on several gastric and duodenal experimental ulcer models were investigated in rats.
(9) alpha-terpineol, 2-n-heptylpyridine, m-cresol and (A)-6-dodecen-4-olide and the investigation of the stereochemistry of the double bond in (Z)-6-dodecen-4-olide by means of iterative computer analysis are described.
(10) The dehalogenation step in the chlorophenol degradation is the cycloisomerization of the cis,cis-chloromuconic acid to 4-carboxymethylenebut-2-en-4-olide in the ortho fission pathway.
(11) 2-Buten-4-olide (2-B-4-O) has been identified in the serum of fasted rats and proved to act as a feeding suppressant.
(12) 4-Carboxymethyl-4-methylbut-2-en-4-olide (4-methyl-2-enelactone) isomerase, transforming 4-methyl-2-enelactone to 3-methyl-2-enelactone, was purified from a derivative strain of Pseudomonas sp.
(13) In an aqueous extract of fruit bodies of Coprinus comatus 3-octanone, 3-octanol, 1-octen-3-ol, 1-octanol, 2-methyl-2-penten-4-olide, 1-dodecanol and caprylic acid were identified conclusively and n-butyric and isobutyric acids preliminarily.
(14) 3-Octanol, 1-octen-3-ol, 1-octanol and 2-methyl-2-penten-4-olide were the volatiles with the strongest flavour.
(15) The bioassays also led to the previously known related diterpenes, kolavenic acid (2) which has not been reported as a constituent of this plant, and 16 alpha-hydroxy-cleroda-3,13(14)Z-dien-15,16-olide (1) which is previously known to be in this plant.
(16) 4-Phenyl-2,3-dihydroxy-2-buten-4-olide (PDHB) and 4-phenyl-2,3-dioxo-4-butenolide (PDOB) accelerated LA peroxidation in 10% EtOH.
(17) 1H-Indolo[3',2':4,5]pyrido[3,2-b]-2-penten-5-olide (6) and 1H,5H-indolo[3',2'-c]-6,7-dihydro-2-pyridone (7), rigid analogues of methyl 4-ethyl-beta-carboline-3-carboxylate (8) and N-methyl-4-ethyl-beta-carboline-3-carboxamide (9), respectively, were synthesized and their in vitro binding affinities to the central type benzodiazepine receptors were compared.
(18) Select compounds were found to be active at concentrations lower than 5 X 10(-5) M. In particular, the compound 2 alpha-bromo-3 beta-hydroxy-6 beta H-eudesm-11-en-6,13-olide exhibits an extremely low ID50 value at 0.33 X 10(-6) M. Some relationships between chemical structure and cytotoxic activity are suggested, i.e.
(19) Reaction of 1 with hot acetic anhydride-sodium acetate gave a approximately 1:2 mixture of (E)- and (Z)-2-acetamido-6-acetoxyhexa-2,4-dien-4-olide (6-E and 6-Z).
(20) Estrous cycling female Wistar rats were treated ip with 2-buten-4-olide (0, 30 or 100 mg.kg-1.day-1) for 2 weeks.
Slid
Definition:
() imp. & p. p. of Slide.
(imp.) of Slide
() of Slide
Example Sentences:
(1) I remember the way I slid sideways through rows of desks, my arms crossed over my chest.
(2) The unemployment rate among 16- to 24-year-olds slid to 19.3%, from 20.7% in the three months to March.
(3) Gerard Piqué slid in and inexplicably handled Marcelo’s cross.
(4) The defender took a quick throw-in on the right wing in the 17th minute back to Hugo Lloris and, after a comical exchange of passes with the Tottenham goalkeeper, he inadvertently slid the ball back inside to Lee Cattermole, who finished precisely into the bottom corner from 25 yards out.
(5) Then Wigan were level, as Sammon slid between two West Ham defenders to turn home his shot, and all the desire and inspiration drained from Grant's side.
(6) A Federal Aviation Administration spokeswoman, Kathleen Bergen, said the CRJ2 aircraft had landed safely and was turning off the runway on to a taxiway when it slid into the snow.
(7) We trained just a little bit, but Ramires slid and has a muscular injury.
(8) The prosthetic testicle is inserted through an inguinal incision and slid into the scrotum.
(9) After picking up an early booking, Ramos spent the rest of the match apparently chasing another, though it took until the 84th minute for Alejandro Hernández to finally reach to his pocket and and show the second yellow, when Ramos needlessly slid through the back of Luis Suárez.
(10) The graft is slid under this bridge, placed onto the roughened surface of the carpus and pushed under the operculum raised at the base of the 2nd and 3rd metacarpals.
(11) In the 10.40m column, the snails slid downward to a depth of 4m or descended suddenly all the way to the bottom.
(12) Interestingly, honest individuals were initially shielded from taking antisocial decisions – but, with time, even they slid down the slippery, corrupting slope of power.
(13) Cameron Borthwick-Jackson had played Costa onside and slid in desperately to try and intercept, only for his tackle to take the ball away from an on-rushing De Gea and neatly into the striker’s path.
(14) The fighting has often slid into horror and depravity over the past 22 months.
(15) So he slid farther forward and got hold of Rob's waist and pulled him the rest of the way out.
(16) Abe says he wants to raise the number of women in the workforce to revive the economy, which has slid back into recession for the fifth time in seven years.
(17) He's staying at Stoke, who presumably wanted a bit more than the £5m that was slid across the table by QPR suits.
(18) Giggs and Bardsley slid in, with the United man winning the race but not preventing a goal.
(19) Ronald Koeman accused Sadio Mané and Victor Wanyama of “lacking focus” and letting the club down as Saints slid further down the table with a fourth consecutive away defeat.
(20) The study showed that the number of PFCs by the Cunningham slid was greater than that observed by the gel technique of Trump at the same lymphocyte concentration.