(a.) Free of access; not shut up; not closed; affording unobstructed ingress or egress; not impeding or preventing passage; not locked up or covered over; -- applied to passageways; as, an open door, window, road, etc.; also, to inclosed structures or objects; as, open houses, boxes, baskets, bottles, etc.; also, to means of communication or approach by water or land; as, an open harbor or roadstead.
(a.) Free to be used, enjoyed, visited, or the like; not private; public; unrestricted in use; as, an open library, museum, court, or other assembly; liable to the approach, trespass, or attack of any one; unprotected; exposed.
(a.) Free or cleared of obstruction to progress or to view; accessible; as, an open tract; the open sea.
(a.) Not drawn together, closed, or contracted; extended; expanded; as, an open hand; open arms; an open flower; an open prospect.
(a.) Without reserve or false pretense; sincere; characterized by sincerity; unfeigned; frank; also, generous; liberal; bounteous; -- applied to personal appearance, or character, and to the expression of thought and feeling, etc.
(a.) Not concealed or secret; not hidden or disguised; exposed to view or to knowledge; revealed; apparent; as, open schemes or plans; open shame or guilt.
(a.) Not of a quality to prevent communication, as by closing water ways, blocking roads, etc.; hence, not frosty or inclement; mild; -- used of the weather or the climate; as, an open season; an open winter.
(a.) Not settled or adjusted; not decided or determined; not closed or withdrawn from consideration; as, an open account; an open question; to keep an offer or opportunity open.
(a.) Free; disengaged; unappropriated; as, to keep a day open for any purpose; to be open for an engagement.
(a.) Uttered with a relatively wide opening of the articulating organs; -- said of vowels; as, the an far is open as compared with the a in say.
(a.) Uttered, as a consonant, with the oral passage simply narrowed without closure, as in uttering s.
(a.) Not closed or stopped with the finger; -- said of the string of an instrument, as of a violin, when it is allowed to vibrate throughout its whole length.
(a.) Produced by an open string; as, an open tone.
(n.) Open or unobstructed space; clear land, without trees or obstructions; open ocean; open water.
(v. t.) To make or set open; to render free of access; to unclose; to unbar; to unlock; to remove any fastening or covering from; as, to open a door; to open a box; to open a room; to open a letter.
(v. t.) To spread; to expand; as, to open the hand.
(v. t.) To disclose; to reveal; to interpret; to explain.
(v. t.) To make known; to discover; also, to render available or accessible for settlements, trade, etc.
(v. t.) To enter upon; to begin; as, to open a discussion; to open fire upon an enemy; to open trade, or correspondence; to open a case in court, or a meeting.
(v. t.) To loosen or make less compact; as, to open matted cotton by separating the fibers.
(v. i.) To unclose; to form a hole, breach, or gap; to be unclosed; to be parted.
(v. i.) To expand; to spread out; to be disclosed; as, the harbor opened to our view.
(v. i.) To begin; to commence; as, the stock opened at par; the battery opened upon the enemy.
(v. i.) To bark on scent or view of the game.
Example Sentences:
(1) says Gregg Wallace opening the new series of Celebrity MasterChef (Mon-Fri, 2.15pm, BBC1).
(2) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(3) His son, Karim Makarius, opened the gallery to display some of the legacy bequeathed to him by his father in 2009, as well as the work of other Argentine photographers and artists – currently images by contemporary photographer Facundo de Zuviria are also on show.
(4) Blatter requires a two-thirds majority of the 209 voters to triumph in the opening round, with a simple majority required if it goes to a second round.
(5) Clonazepam was added to the treatment of patients with poorly controlled epilepsy in a double-blind trial and an open trial.
(6) By hybridization studies, three plasmids in two forms (open circular and supercoiled) were detected in the strain A24.
(7) It is the only fully-fledged casino to open in the region, outside Lebanon.
(8) Sixty-six patients were followed for 12 months in an open safety study.
(9) The PUP founder made the comments at a voters’ forum and press conference during an open day held at his Palmer Coolum Resort, where he invited the electorate to see his giant robotic dinosaur park, memorabilia including his car collection and a concert by Dean Vegas, an Elvis impersonator.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) An opening wedge osteotomy is then directed posterior-dorsal to anterior-plantar, to effectively plantarflex the posterior aspect of the calcaneus.
(12) … or a theatre and concert hall There are a total of 16 ghost stations on the Paris metro; stops that were closed or never opened.
(13) The decline in the frequency of serious complications was primarily due to a decrease in the proportion of patients with open fractures treated with plate osteosynthesis from nearly 50% to 19%.
(14) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(15) 'The French see it as an open and shut case,' says a Paris-based diplomat.
(16) The White House denied there had been an agreement, but said it was open in principle to such negotations.
(17) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(18) The data indicate greater legitimacy and openness in discussing holocaust-related issues in the homes of ex-partisans than in the homes of ex-prisoners in concentration camps.
(19) He also plans to build a processing facility where tourists can gain firsthand experience of the fisheries industry, and to open a restaurant.
(20) He had been just asked to open their new town hall, in the hope he might donate a Shakespeare statue.
Perforate
Definition:
(v.) To bore through; to pierce through with a pointed instrument; to make a hole or holes through by boring or piercing; to pierce or penetrate the surface of.
(a.) Alt. of Perforated
Example Sentences:
(1) report the complications registered, in particular: lead's displacing 6.2%, run away 0.7%, marked hyperthermya 0.0%, haemorrage 0.4%, wound dehiscence 0.3%, asectic necrosis by decubitus 5%, septic necrosis 0.3%, perforation of the heart 0.2%, pulmonary embolism 0.1%.
(2) Pitlike surface structures seen in negatively stained whole cells and thin sections were correlated with periodically spaced perforations of the rigid sacculus.
(3) Compliance during dehydration was 7.6 and 12.5% change in IFV per millimeter Hg fall in IFP (micropipettes) in skin and muscle, respectively, whereas compliance in subcutis based on perforated capsule pressure was 2.0% change in IFV per millimeter Hg.
(4) The perforant pathway and fimbria fornix were transected to label afferent fibers to NPY-positive cells.
(5) As to complications they recorded in one case mucosal bleeding after gastrofiberoptic polypectomy and in one case a covered perforation of the sigmoid at the site of colonoscopic polypectomy.
(6) By way of major complications, merely one perforation occurred.
(7) Autopsy data of all patients who received EVS and who died (32 patients, 100%) during this period were available to confirm the diagnosis of perforation.
(8) The results of a prospective inquiry into the aspirin taking habits of a consecutive series of 118 patients admitted to a large general hospital with acute perforation of peptic ulcer are presented.
(9) No perforations, stenoses or thermic lesions after wound healing were observed.
(10) Other serious complications were reservoir perforation during catheterisation in 3 and development of stones in the reservoir in 2 patients.
(11) Major reported complications include hemorrhage, perforation, biliary and pancreatic obstruction, and inflammation with intestinal obstruction.
(12) A retrospective study was conducted into 136 patients who had received surgical treatment for perforated gastroduodenal ulcers, with the view to establishing postoperative lethality and morbidity (comparing simple suturing with definitive ulcer surgery).
(13) Three cases of gastroduodenal perforation and one case of ulceration and extreme thinning of the gastric wall occurred in preterm babies treated with dexamethasone for bronchopulmonary dysplasia.
(14) The energy required for perforation from the external surface to the anterior chamber was the same as the energy required for ab interno perforation.
(15) Cholecystokinin (CCK) as the sulfated (CCK-8S) and unsulfated (CCK-8U) octapeptide sequences, and CR 1409 were administered intraventricularly while the action potential (EAP) in the granular cell layer of the hippocampal dentate gyrus evoked by perforant path stimulation was recorded.
(16) At first the prognosis of perforating keratoplasty improved because of better surgical techniques, so that the number of indications increased.
(17) a) To determine the frequency of perforations in latex surgical gloves before, during, and after surgical and dental procedures; b) to evaluate the topographical distribution of perforations in latex surgical gloves after surgical and dental procedures; and c) to validate methods of testing for latex surgical glove patency.
(18) Perforations of the left atrial or ventricular wall and extravasations of contrast medium during transseptal left heart catheterisation or angiocardiography can be eliminated by replacing the normally used transseptal catheters by Pigtail-catheters.
(19) In the cis-trans axis of the Golgi apparatus the following compartments were observed: (a) On the cis face there was a continuous osmiophilic tubular network referred to as the cis element; (b) a cis compartment composed of 3 or 4 NADPase-positive saccules perforated with pores in register forming wells that contained small vesicles; (c) a trans compartment composed of 1 or 2 TPPAse-positive elements underlying the NADPase ones, followed by 1 or 2 CMPase-positive elements that showed a flattened saccular part continuous with a network of anastomotic tubules.
(20) Dairy pipeline cleaners were the single most common causative substance, injuring ten toddlers (mean age 1.6 years), perforating the esophagus in two.