(n.) Originally, a medicine of a thicker consistence than sirup, prepared with opium.
(n.) Any medicine that contains opium, and has the quality of inducing sleep or repose; a narcotic.
(n.) Anything which induces rest or inaction; that which quiets uneasiness.
(a.) Inducing sleep; somniferous; narcotic; hence, anodyne; causing rest, dullness, or inaction; as, the opiate rod of Hermes.
(v. t.) To subject to the influence of an opiate; to put to sleep.
Example Sentences:
(1) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
(2) Opiate agonists and endogenous opioid peptides inhibit electrolyte secretion both in vitro and in vivo.
(3) It appears that tricyclic antidepressants act in a fashion different from opiate drugs that alter the sensory discriminative component of pain.
(4) The results are discussed with reference to the possible mechanism(s) via which injected and endogenous opiates may affect motor performance by attenuating GABA transmission in the nigra.
(5) Pharmacological data suggest that opiates, acting indirectly via the catecholaminergic system, are involved in the inhibition of LH release and the stimulation of PRL secretion.
(6) Such disturbances may be induced by opiates, benzodiazepines, phenothiazines, butyrophenones, ketamine, etomidate, propofol, nitrous oxide, and halogenated inhalation anesthetics as well as by H2-blocking agents such as cimetidine.
(7) From these results, we conclude that opiate peptides are released in response to the suckling stimulus in the cynomolgus monkey and that they mediate the effects of suckling on PRL secretion in both gonadal-intact and agonadal cynomolgus monkeys.
(8) Its potency is 4-5 times greater than that of the opiate antagonist naloxone.
(9) A cost-effective immunoassay for the detection of opiates in urine has been developed using commercial reagents on a centrifugal analyser.
(10) Drugs used to promote food intake and weight gain, such as cyproheptadine, amitriptyline, clonidine and opiate antagonists, have provided disappointing results.
(11) An alternative approach, which correlates the structure-activity data of opiate compounds with that of the enkephalins, is described and shown to produce a model consistent with the available structure-activity data.
(12) However, opiate treatment is not a new therapeutic concept in psychiatry.
(13) The inhibitory response was not decreased by treatment with atropine, hexamethonium, yohimbine or naloxone, suggesting that muscarinic, nicotinic, alpha 2 adrenergic or opiate receptors were not being stimulated.
(14) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(15) We report that exposure of rat spinal cord-dorsal root ganglion cocultured neurons to kappa-opiate agonist is accompanied by a 60-70% reduction in the level of the alpha i subunit of GTP-binding proteins.
(16) Cerebrospinal fluid (CSF) opiate activity has been found to be elevated in two studies.
(17) PBEir increased with both opiates immediately after initiation of CPB and remained so during the rest of the study.
(18) Diclofenac is an alternative to opiates in the management of postoperative pain.
(19) On the other hand, if the tissue-derived opiates were from prodynorphin, only Leu-enkephalin should be found.
(20) Analysis of patient questionnaires suggests more enthusiasm for patient-controlled analgesia, but in this study, it was difficult to clearly demonstrate any significant advantage for pain management or amount of opiate administered.
Opium
Definition:
(n.) The inspissated juice of the Papaver somniferum, or white poppy.
Example Sentences:
(1) The only entirely original stage work from this period was the spectacular one-man show Needles And Opium in 1991, which intermingled stories of love and addiction from the lives of Jean Cocteau and Miles Davis with an account of the meltdown of one of Lepage's own long-term relationships.
(2) Social changes going on in the society were reflected in choice of substance forms by younger people as compared to their elders (e.g., cigarettes vs pipes or cigars, heroin vs opium, manufactured vs village-produced alcohol).
(3) American frustrations burst into the open in October 2009 when serving and retired officials told the New York Times Karzai was a key player in Afghanistan's illegal opium trade, which helps fund the Taliban insurgency, while on the CIA payroll.
(4) A transformation of the corrupt economy could take up to two decades, and opium production is likely to climb beyond 2013's worrying levels before it falls again, said Jean-Luc Lemahieu, outgoing head of the UN office on drugs and crime in Afghanistan .
(5) Athletic elitism, the glorification of the human body, has succeeded religion as Marx's opium of the people.
(6) Cannabis and opium use has been in Nepal for centuries and in the past they did not pose much of a problem.
(7) In Henley, he encountered with interest the bookshop-owning lesbians who had taken opium with Cocteau, and a prim, elderly lady who had, in her youth, urinated regularly upon pioneering sexologist Havelock Ellis.
(8) But the ACMD research clearly found that the majority of people were not “parked” on opium substitution treatment for long periods of time, with only 10-15% receiving treatment for more than five years.
(9) With lots of water and fertile land, Sangin is perfect for growing the poppies currently being harvested for their opium sap.
(10) Subjects with a positive family history of opium use had an earlier age of onset than the subjects without a family history of opium use.
(11) Two ethnic groups in Laos were compared: the Hmong (or Meo), a tribal group with access to opium in their homes; and the Lao, a peasant people with more limited access, usually in opium dens.
(12) The time-course of changes in vegetative tests was studied in 47 men suffering from stage II opium dependence.
(13) Fifty-six addicted "world travelers" were studied at a treatment facility for opium addicts in Laos.
(14) Cash crops have diversified and replaced the former opium fields; the economy is moving away from a subsistence and cash economy to a mostly cash economy.
(15) They may well also be driving the Taliban effort in Helmand, since control of the opium-rich province would hand a major political advantage to whichever leader achieved it.
(16) Naltrexone blocked opioid-induced euphoria and decreased the craving for opium, but it did not inhibit drug usage.
(17) These studies contribute to the evidence that different cytochrome P-450-dependent mono-oxygenase systems are involved in the O- and N-dealkylation of opium alkaloids.
(18) Opium poppy latex contains a group of laticifer-specific, low-molecular-weight polypeptides called major latex proteins (MLPs).
(19) Communities raising opium poppy as a cash crop had highest crude rates of addiction (7.0-9.8 addicts per 100 people).
(20) The British prosecuted two opium wars in the cause of freedom to export and sell the produce of the East India Company's Bengal factories.