(n.) Originally, a medicine of a thicker consistence than sirup, prepared with opium.
(n.) Any medicine that contains opium, and has the quality of inducing sleep or repose; a narcotic.
(n.) Anything which induces rest or inaction; that which quiets uneasiness.
(a.) Inducing sleep; somniferous; narcotic; hence, anodyne; causing rest, dullness, or inaction; as, the opiate rod of Hermes.
(v. t.) To subject to the influence of an opiate; to put to sleep.
Example Sentences:
(1) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
(2) Opiate agonists and endogenous opioid peptides inhibit electrolyte secretion both in vitro and in vivo.
(3) It appears that tricyclic antidepressants act in a fashion different from opiate drugs that alter the sensory discriminative component of pain.
(4) The results are discussed with reference to the possible mechanism(s) via which injected and endogenous opiates may affect motor performance by attenuating GABA transmission in the nigra.
(5) Pharmacological data suggest that opiates, acting indirectly via the catecholaminergic system, are involved in the inhibition of LH release and the stimulation of PRL secretion.
(6) Such disturbances may be induced by opiates, benzodiazepines, phenothiazines, butyrophenones, ketamine, etomidate, propofol, nitrous oxide, and halogenated inhalation anesthetics as well as by H2-blocking agents such as cimetidine.
(7) From these results, we conclude that opiate peptides are released in response to the suckling stimulus in the cynomolgus monkey and that they mediate the effects of suckling on PRL secretion in both gonadal-intact and agonadal cynomolgus monkeys.
(8) Its potency is 4-5 times greater than that of the opiate antagonist naloxone.
(9) A cost-effective immunoassay for the detection of opiates in urine has been developed using commercial reagents on a centrifugal analyser.
(10) Drugs used to promote food intake and weight gain, such as cyproheptadine, amitriptyline, clonidine and opiate antagonists, have provided disappointing results.
(11) An alternative approach, which correlates the structure-activity data of opiate compounds with that of the enkephalins, is described and shown to produce a model consistent with the available structure-activity data.
(12) However, opiate treatment is not a new therapeutic concept in psychiatry.
(13) The inhibitory response was not decreased by treatment with atropine, hexamethonium, yohimbine or naloxone, suggesting that muscarinic, nicotinic, alpha 2 adrenergic or opiate receptors were not being stimulated.
(14) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(15) We report that exposure of rat spinal cord-dorsal root ganglion cocultured neurons to kappa-opiate agonist is accompanied by a 60-70% reduction in the level of the alpha i subunit of GTP-binding proteins.
(16) Cerebrospinal fluid (CSF) opiate activity has been found to be elevated in two studies.
(17) PBEir increased with both opiates immediately after initiation of CPB and remained so during the rest of the study.
(18) Diclofenac is an alternative to opiates in the management of postoperative pain.
(19) On the other hand, if the tissue-derived opiates were from prodynorphin, only Leu-enkephalin should be found.
(20) Analysis of patient questionnaires suggests more enthusiasm for patient-controlled analgesia, but in this study, it was difficult to clearly demonstrate any significant advantage for pain management or amount of opiate administered.
Optate
Definition:
(v. i.) To choose; to wish for; to desire.
Example Sentences:
(1) In nursing, a feminist perspective requires an uncompromising questioning of the forces that divide us from one another, the ethics of our actions, and our co-optation into the unhealthy environment of the current health care system.
(2) Thirty-eight ICUs were chosen by co-optation rather than by randomization.
(3) All three possibilities: co-optation, subordination and nationalization are problematic as far as chiropractic is concerned.
(4) Beijing cannot assume it can adopt its old strategies like co-optation to deal with this new generation of democrat inside the legislature and also outside.” Jason Ng, the author of Umbrellas in Bloom, a book about Hong Kong’s protest generation, predicted political fireworks as highly politicised youngsters picked up the mantle from traditional mainstream democracy figures, known as the pan-democrats.
(5) The very high hepatic stricture may present an almost insoluble problem and the "mucosal graft" of Rodney Smith is the optative operation.