(a.) Pertaining to the origin or beginning; preceding all others; first in order; primitive; primary; pristine; as, the original state of man; the original laws of a country; the original inventor of a process.
(a.) Not copied, imitated, or translated; new; fresh; genuine; as, an original thought; an original process; the original text of Scripture.
(a.) Having the power to suggest new thoughts or combinations of thought; inventive; as, an original genius.
(a.) Before unused or unknown; new; as, a book full of original matter.
(n.) Origin; commencement; source.
(n.) That which precedes all others of its class; archetype; first copy; hence, an original work of art, manuscript, text, and the like, as distinguished from a copy, translation, etc.
(n.) An original thinker or writer; an originator.
(n.) A person of marked eccentricity.
(n.) The natural or wild species from which a domesticated or cultivated variety has been derived; as, the wolf is thought by some to be the original of the dog, the blackthorn the original of the plum.
Example Sentences:
(1) Our results suggest that the peripheral sensitivity to hypoxia declined more than that to CO2, implying a peripheral chemoreceptor origin for hypoxic ventilatory decline.
(2) These immunocytochemical studies clearly demonstrated that cells encountered within the fibrous intimal thickening in the vein graft were inevitably smooth muscle cell in origin.
(3) The nuclear origin of the Ha antigen was confirmed by the speckled nuclear immunofluorescence staining pattern given by purified antibody to Ha obtained from a specific immune precipitate.
(4) The origin of the aorta and pulmonary artery from the right ventricle is a complicated and little studied congenital cardiac malformation.
(5) The origins of aging of higher forms of life, particularly humans, is presented as the consequence of an evolved balance between 4 specific kinds of dysfunction-producing events and 4 kinds of evolved counteracting effects in long-lived forms.
(6) These cells contained organelles characteristic of the maturation stage ameloblast and often extended to the enamel surface, suggesting a possible origin from the ameloblast layer.
(7) We conclude that chloramphenicol resistance encoded by Tn1696 is due to a permeability barrier and hypothesize that the gene from P. aeruginosa may share a common ancestral origin with these genes from other gram-negative organisms.
(8) Typological and archaeological investigations indicate that the church building represents originally the hospital facility for the lay brothers of the monastery, which according to the chronicle of the monastery was built in the beginning of the 14th century.
(9) Plasma NPY correlated better with plasma norepinephrine than with epinephrine, indicating its origin from sympathetic nerve terminals.
(10) Interadjudicator agreement was stronger on 'originality' than on 'aesthetic pleasingness'.
(11) One rare case of blind-ending branch originating in the upper third of the ureter are described.
(12) It is my desperate hope that we close out of town.” In the book, God publishes his own 'It Getteth Better' video and clarifies his original writings on homosexuality: I remember dictating these lines to Moses; and afterward looking up to find him staring at me in wide-eyed astonishment, and saying, "Thou do knowest that when the Israelites read this, they're going to lose their fucking shit, right?"
(13) As the requirements to store and display these images increase, the following questions become important: (a) What methods can be used to ensure that information given to the physician represents the originally acquired data?
(14) The condition is compared to extrahepatic and intrahepatic biliary atresia of man and evidence is presented for regarding this case to be one of extrahepatic origin.
(15) The position of the cyst supports the theory that branchial cysts are congenital in origin.
(16) heterografts of GW-39, a CEA-producing colonic tumor of human origin, was demonstrated in radioimmunoassay using radioiodinated CEA purified from GW-39.
(17) The committee reviewed the history, original intent, current purpose, and effectiveness of meetings held on the unit; when problems were identified, suggestions for change were formulated.
(18) The relative strength of the progressions varies with excitation wavelength and this, together with the absence of a common origin, indicates the existence of two independent emitting states with 0-0' levels separated by either 300 or 1000 cm-1.
(19) Sickle and normal discocytes both showed membrane elasticity with reversion to original cell shape following release of the cell from its aspirated position at the pipette tip.
(20) With respect to family environment, a history of sexual abuse was associated with perceptions that families of origin had less cohesion, more conflict, less emphasis on moral-religious matters, less emphasis on achievement, and less of an orientation towards intellectual, cultural, and recreational pursuits.
Primordial
Definition:
(a.) First in order; primary; original; of earliest origin; as, primordial condition.
(a.) Of or pertaining to the lowest beds of the Silurian age, corresponding to the Acadian and Potsdam periods in American geology. It is called also Cambrian, and by many geologists is separated from the Silurian.
(a.) Originally or earliest formed in the growth of an individual or organ; as, a primordial leaf; a primordial cell.
(n.) A first principle or element.
Example Sentences:
(1) In contrast, in primordial follicles, FSH was restricted to the germ cell but was present in both the oocyte cytoplasm and germinal vesicle.
(2) Renal arteriography is therefore alone capable of answering two primordial questions: "Must surgery be undertaken and when operating, what surgical tactics to adopt".
(3) This primordial role explains the wide variety of tissues, ranging from the central and peripheral nervous system to the vascular system, that are affected by FGF during the late embryonic, neonatal, and adult phases of development.
(4) Indirect immunofluorescence studies with four monoclonal antibodies raised against carp spermatozoa revealed that monoclonal antibody WCS 29 stained the outer membranes of primordial germ cells in larvae from 3 days after fertilization.
(5) After the treatment in toto of the embryos from various species of Anura by cAMP, the number of primordial germ cells (PGC) in genital ridges is strongly reduced; the most part of the PGC are found in the endoderm.
(6) Mouse lymphocytes and STO fibroblasts were negative, whereas F9 teratocarcinoma cells, intestinal epithelial cells, and rat fetal primordial germ cells were all found to be highly positive for APase activity, in agreement with published results on APase localization in these cells.
(7) This sequence of events suggests that receptor formation may be induced by innervation of primordial cells within the epidermis.
(8) Laparoscopic directed ovarian biopsies show primordial follicles in one and a corpus luteum in the other.
(9) Plastic responses in leaf form resulting from ontogenetic or external influences are initiated very early in primordial development and are brought about by effects on the rate and direction of cell division and expansion in different regions of the primordium.
(10) The primordial ratio was supposed to shift to the modern one guided by the action of primitive nucleotides.
(11) Evidence suggests that cAMP production is not a primordial step in the response to androgen since dibutyryl cAMP did not mimick the androgenic effect, theophylline did not potentiate the response and alpha,beta-methylene ATP, which competitively inhibits adenyl cyclase, failed to alter the androgenic effect.
(12) In the ooplasm the transosome takes part in the development of primordial yolk granules.
(13) Moreau de Tours's classical studies about haschisch had pointed out to a rich symptomatology: visual and auditive hallucinations preceded by the "primordial effect": "the dissociation of ideas".
(14) The resulting space is not homologous with the primordial amniotic cavity; instead, it is a transitory tropho-epiblastic cavity.
(15) In embryos with 6.5-6.7 mm NRL, a part of the primordial proper esophagus extended to the dorsal side of the primordial stomach.
(16) Besides this areas of the primordial germinogen cell generation are found among the cells lining the system of labyrinths and channels of the yolk sac tumour.
(17) It is concluded that exposure of B6 mice to a single dose of MC results in atresia of oocytes in primordial and small primary follicles.
(18) Primordial germ cells (PGCs), which formed in 78% of cases when the presumptive ventral half to the embryo was cultured, occurred in only 48% of cases when the two ventral vegetal blastomeres were cultured alone.
(19) Sympathetic neurotransmitters have been shown to be present in the ovary of the rat during early postnatal development and to affect steroidogenesis before the ovary becomes responsive to gonadotropins, and before the first primordial follicles are formed.
(20) Gonadal biopsy was done on the patients, which disclosed no evidence of primordial follicles in one and severe reduction in the other.