(a.) Pertaining to the origin or beginning; preceding all others; first in order; primitive; primary; pristine; as, the original state of man; the original laws of a country; the original inventor of a process.
(a.) Not copied, imitated, or translated; new; fresh; genuine; as, an original thought; an original process; the original text of Scripture.
(a.) Having the power to suggest new thoughts or combinations of thought; inventive; as, an original genius.
(a.) Before unused or unknown; new; as, a book full of original matter.
(n.) Origin; commencement; source.
(n.) That which precedes all others of its class; archetype; first copy; hence, an original work of art, manuscript, text, and the like, as distinguished from a copy, translation, etc.
(n.) An original thinker or writer; an originator.
(n.) A person of marked eccentricity.
(n.) The natural or wild species from which a domesticated or cultivated variety has been derived; as, the wolf is thought by some to be the original of the dog, the blackthorn the original of the plum.
Example Sentences:
(1) Our results suggest that the peripheral sensitivity to hypoxia declined more than that to CO2, implying a peripheral chemoreceptor origin for hypoxic ventilatory decline.
(2) These immunocytochemical studies clearly demonstrated that cells encountered within the fibrous intimal thickening in the vein graft were inevitably smooth muscle cell in origin.
(3) The nuclear origin of the Ha antigen was confirmed by the speckled nuclear immunofluorescence staining pattern given by purified antibody to Ha obtained from a specific immune precipitate.
(4) The origin of the aorta and pulmonary artery from the right ventricle is a complicated and little studied congenital cardiac malformation.
(5) The origins of aging of higher forms of life, particularly humans, is presented as the consequence of an evolved balance between 4 specific kinds of dysfunction-producing events and 4 kinds of evolved counteracting effects in long-lived forms.
(6) These cells contained organelles characteristic of the maturation stage ameloblast and often extended to the enamel surface, suggesting a possible origin from the ameloblast layer.
(7) We conclude that chloramphenicol resistance encoded by Tn1696 is due to a permeability barrier and hypothesize that the gene from P. aeruginosa may share a common ancestral origin with these genes from other gram-negative organisms.
(8) Typological and archaeological investigations indicate that the church building represents originally the hospital facility for the lay brothers of the monastery, which according to the chronicle of the monastery was built in the beginning of the 14th century.
(9) Plasma NPY correlated better with plasma norepinephrine than with epinephrine, indicating its origin from sympathetic nerve terminals.
(10) Interadjudicator agreement was stronger on 'originality' than on 'aesthetic pleasingness'.
(11) One rare case of blind-ending branch originating in the upper third of the ureter are described.
(12) It is my desperate hope that we close out of town.” In the book, God publishes his own 'It Getteth Better' video and clarifies his original writings on homosexuality: I remember dictating these lines to Moses; and afterward looking up to find him staring at me in wide-eyed astonishment, and saying, "Thou do knowest that when the Israelites read this, they're going to lose their fucking shit, right?"
(13) As the requirements to store and display these images increase, the following questions become important: (a) What methods can be used to ensure that information given to the physician represents the originally acquired data?
(14) The condition is compared to extrahepatic and intrahepatic biliary atresia of man and evidence is presented for regarding this case to be one of extrahepatic origin.
(15) The position of the cyst supports the theory that branchial cysts are congenital in origin.
(16) heterografts of GW-39, a CEA-producing colonic tumor of human origin, was demonstrated in radioimmunoassay using radioiodinated CEA purified from GW-39.
(17) The committee reviewed the history, original intent, current purpose, and effectiveness of meetings held on the unit; when problems were identified, suggestions for change were formulated.
(18) The relative strength of the progressions varies with excitation wavelength and this, together with the absence of a common origin, indicates the existence of two independent emitting states with 0-0' levels separated by either 300 or 1000 cm-1.
(19) Sickle and normal discocytes both showed membrane elasticity with reversion to original cell shape following release of the cell from its aspirated position at the pipette tip.
(20) With respect to family environment, a history of sexual abuse was associated with perceptions that families of origin had less cohesion, more conflict, less emphasis on moral-religious matters, less emphasis on achievement, and less of an orientation towards intellectual, cultural, and recreational pursuits.
Transcribe
Definition:
(v. t.) To write over again, or in the same words; to copy; as, to transcribe Livy or Tacitus; to transcribe a letter.
Example Sentences:
(1) RNA transcribed in vitro from the early region of bacteriophage T3 or T7 was translated by cytoplasmic ribosomes which synthesized protein in cell-free systems prepared from mammalian cells and wheat germ.
(2) The gene, which is located at chromosome XIII, is transcribed as a mRNA of about 2.7 kilobases, and the amount of message has been found to increase 3- to 4-fold during the culture.
(3) RNA preparations were reverse-transcribed, amplified by a polymerase chain reaction (PCR), and separated by electrophoresis.
(4) Early after infection, the E3 promoter is used to make mainly mRNAs a and h. Late after infection, the E3 promoter appears to be shut off and the major late promoter is used to make mainly mRNAs d and e. The late L4 mRNA 3' end site is not used early even though early E3 pre-mRNAs transcribe through the L4 RNA 3' end site.
(5) Thus, hyp does not appear to affect metastable variation but does affect the level of transcription of the pilA gene in the ON (transcribed) mode.
(6) MDR1-containing amplicons may include a number of additional transcribed genes that do not appear to contribute to multidrug resistance.
(7) In vivo, ribosomal RNA of Saccharomyces cerevisiae is transcribed from the light strand of gamma DNA.
(8) Each of the two spliced molecules contains a 5'-terminal leader sequence transcribed from a DNA segment with an estimated length of 60 to 110 nuvleotides.
(9) Sequences representing the entire TIR are transcribed into poly(A)+ mRNA at both early and late times in the infection.
(10) VZV TK templates were linearized at internal restriction sites and RNAs transcribed from these templates directed the synthesis of polypeptides with sizes consistent with the colinearity of the VZV TK gene.
(11) Oligodeoxynucleotides related to the non-transcribed DNA strands can effectively inhibit the RNA synthesis catalyzed by E. coli RNA polymerase.
(12) To identify the molecular defect in a patient with the intermediate form of the disease, arylsulfatase B mRNA from his fibroblasts was reverse-transcribed, amplified by the polymerase chain reaction, and subcloned.
(13) Similar sequence periodicities are found in the internal control regions of other genes transcribed by RNA polymerase III, and also in the SV40 promoter and a monkey gene region to which the transcription factor Sp1 binds.
(14) Nevertheless, XA is transcribed into a stable 2.6-kb polyadenylated RNA that is expressed uniquely in the adrenal gland.
(15) To determine which enzymes are responsible for the processing cleavages of ribosomal RNA transcripts in Escherichia coli, we constructed a mutant strain lacking RNAase III and containing a thermolabile RNAase P. At the nonpermissive temperature, this strain accumulates a novel "19S" RNA species which contains 17S precursor rRNA sequences covalently linked to tRNA sequences transcribed from the ribosomal RNA spacer region between the 16S and the 23S rRNA cistrons.
(16) RNA transcribed by RNA polymerase II on denatured DNA was only large RNA around 28S.
(17) Expression of the N-methyl-D-aspartate receptor gene during long-term administration of competitive and non-competitive NMDA antagonists was studied in rat brain using antisense cRNA transcribed from reverse transcriptase-polymerase chain reaction (RT-PCR)-generated rat NMDA receptor cDNA.
(18) In addition, the transcriptional behaviour of this tRNALeuCUG gene in various in vitro systems is described and it seems that, although the gene is transcribed in all test systems, the very A + T-rich 5'-flanking sequence of this particular gene may be somewhat inhibitory to transcription in vitro.
(19) A combination of techniques for reverse transcribing mRNA into cDNA and the incorporation of 32P-gamma ATP into the polymerase chain reaction (PCR)-generated fragments allowed us to detect beta 2-AR mRNA in surgically excised thyroid specimens.
(20) A new repetitive DNA region was identified in the non-transcribed spacer of human rDNA, namely a long (4.6 kb) sequence motif (Xbal element) was present in two copies.