What's the difference between osteoclast and osteoplast?
Osteoclast
Definition:
(n.) A myeloplax.
(n.) An instrument for performing osteoclasis.
Example Sentences:
(1) A novel staining procedure for enumerating osteoclasts on neonatal mouse calvaria with the vital fluorescent dye acridine orange is described.
(2) Light microscopic autoradiography after labeling of the cultures with tritiated thymidine showed that both RA and 1,25-(OH)2D3 induced osteoclast differentiation from proliferating and postmitotic precursors.
(3) We have previously shown that multinucleated cells (MNC) with many features of the osteoclast phenotype form in long term human marrow cultures.
(4) Osteoclasts dissolve bone mineral by the vectorial secretion of hydrogen ion at their osseous attachment site.
(5) Superoxide dismutase (SOD) inhibited the accumulation of formazan by the isolated osteoclasts.
(6) Addition of extracellular Ca2+ (5 mM CaCl2), a potent osteoclast inhibitor, increased [Ca2+]i in all osteoclasts, but 10(-6) M salmon calcitonin (sCT) did so only in a subpopulation of osteoclasts.
(7) Osteoclasts were isolated from the long bones of neonatal rabbits and cultured on devitalized bovine bone slices for 8, 24, 48 and 72 h with and without prostaglandin E2 (PGE2) (10(-6) M).
(8) Marrow macrophages, at various stages of in vitro maturation, also possess lysozyme mRNA but in amounts approximately two to four times lower than osteoclasts.
(9) The use of diphosphonates (bisphosphonates), a group of potent osteoclast inhibitors, is discussed in some detail.
(10) Dimethylamiloride (100 microM) inhibited bone resorption by 80% and 65% when added at t = 0 or 1 hr after osteoclast adherence, but was without effect when added at t = 3 or 6 hr.
(11) These results provide strong evidence for the osteoclastic nature of the giant cells in this variant of the MFH.
(12) Since the osteoclast plays an important role in the resorption and remodeling of bone in these middle ear diseases, the source, physiology, and local control of these cells are of prime importance in investigating the pathophysiology of these diseases.
(13) The effects of interleukin-1 did not appear to be related to osteoclast precursor proliferation, since hydroxyurea (which inhibits DNA synthesis in these cultures) had no effect on the response of calvaria calavaria increases osteoclast to interleukin-1.
(14) These results indicate that CT activates PKC in osteoclasts and that this activation, like the activation of cAMP-dependent protein kinase, leads to an inhibition of bone resorption.
(15) Quantitative time-lapse videomicroscopy showed that the CT-induced retraction of osteoclasts also involved activation of the PKC pathway and could therefore be induced by phorbol esters.
(16) Thus, the resorption-antagonizing capacities of EHDP, Cl2MDP and APD reflect metabolic inhibition, with selectivity for the osteoclast resulting from high affinity binding to bone mineral.
(17) NBT staining was detected only in osteoclasts in cultures of resorbing bones.
(18) Band 5 represents the only tartrate-resistant form and is present in bone osteoclasts and in human alveolar macrophages (AMs).
(19) These results suggest that osteoclast resorbs bone by secreting protons through vacuolar H(+)-ATPase.
(20) Hypercalcemia in this model is mediated in part by the effects of PTH-rP to increase osteoclastic bone resorption.
Osteoplast
Definition:
(n.) An osteoblast.
Example Sentences:
(1) Massive osteoplastic bone tumor in hepatocellular carcinoma is very rare.
(2) The types of metastasis expansion in the bones were determined radiologically: the most frequent--osteolytic, less frequent--mixed, and the osteoplastic type (prostate cancer, gall-bladder cancer, and pancreas cancer).
(3) Biopsy was performed in seven patients harbouring osteolytic and osteoplastic lesions of the cervical (3 cases), thoracic (3 cases) and lumbar spine (1 case).
(4) During osteoplastic surgery of the maxillary sinus routinely performed by the author in more than 700 cases since 1973 a piece of bone (the "Bone Lid") including the attached mucosa is cut out of the anterior wall of the maxillary sinus in such a fashion that it serves perfectly to close the opening again as a free graft at the end of the operation.
(5) Unpleasant symptoms such as facial neuralgia and discomfort, were reduced to half after osteoplastic reconstruction of the anterior wall of the maxillary sinus.
(6) Only complete opening combined with complete reconstruction serves really eradicating the pathology completely as well as full reconstruction of the middle ear and the external canal; this means osteoplastic epitympanotomy.
(7) The method of choice for the treatment was the osteoplastic trepanation with a removal of the haematoma.
(8) Surgically, we preferred the transethmoidal route and in some cases the lateral osteoplastic approach.
(9) Nasofrontal duct reconstruction offers more direct access to the ethmoid cell system than osteoplastic flap obliteration.
(10) A rare but distressing complication of frontal embossment was managed after osteoplastic flap surgery.
(11) Patients were treated with a variety of procedures including cranialization (42%), osteoplastic flap and fat obliteration (30%), open reduction and internal fixation of the anterior wall (20%), osteoplastic flap and sinus ablation (6%), and intersinus septectomy (1%).
(12) Osteoplastic trephination and encephalotomy is the principal surgical method.
(13) Surgical interference within the blood supply to the inner ear was responsible for metaplastic bone, and damage to the endosteum by surgery or disease caused osteoplastic bone.
(14) Treatments of PA-III-affected bones with Cl2MDP and x-rays immobilized both osteolytic and osteoplastic processes.
(15) The operative approach and findings of 250 osteoplastic frontal sinusotomy operations performed from 1956 through 1972 at the Massachusetts Eye and Ear Infirmary are reviewed.
(16) This is a report on two cases of an extensive absorption of bone following reimplantation of an osteoplastic flap of the cranial vault.
(17) Those identified as producing mechanical complications clinically, or a 'hot' bone scan by radionuclide study, were regarded as appropriate for osteoplastic frontal sinusectomy for removal of the osteoma; three cases were approached in this way.
(18) Resection trepanation of the skull was carried out in 55 patients, osteoplastic in 23.
(19) Histologically, the tumor was composed of hepatocellular carcinoma, cholangiocarcinoma, and sarcomatous portions, including spindle-shaped, pleomorphic, and osteoplastic varieties.
(20) In the osteoplastic approach the superior and posterior segment of the ear canal wall is temporarily removed.