(a.) Being on the extreme external part; farthest outward; as, the outermost row.
Example Sentences:
(1) Immunohistochemical studies support earlier reports of a rich nerve supply to the posterior longitudinal ligament, a less developed innervation of the anterior ligament and the outermost annular ring, and a total lack of innervation in deeper parts of the intervertebral disc.
(2) A marked, reversible swelling of the outermost layer of the stratum granulosum was observed during short circuiting of the skin compared to the homogeneous appearance of the epithelium under open circuit conditions.
(3) With an ultrathin section preparation of strain ST67P conjugated with ferritin-labelled rabbit anti-homologous strain serum, numerous ferritin granules surrounding the outermost layer of large capsule were electronmicro-scopically demonstrated.
(4) The outermost strands are consistently parallel to the differentiated segment of the plasma membrane, which is invariably associated with surface projections.
(5) Instead there is a complex, tight layer of cells, the interface layer, composed in the innermost portion of the dura mater (the dural border cells) and the outermost portion of the arachnoid (the arachnoid barrier layer).
(6) Sequential removal of layers of the walls of fresh specimens of the gastro-intestinal tract showed the following correlation between the sonographic and histological findings: the innermost and outermost highly echogenic lines correspond to incident and exit echoes.
(7) When there was retraction space, the role of the outermost cells of a nest diminished or disappeared.
(8) What these factors are is as yet not known; however, it is clear that autoantibodies found in high frequency in SS, specifically anti-Ro and anti-La, are associated with HLA class II alleles, found at the HLA-DQA1 and DQB1 loci, which have in common the presence of specific amino acid residues that are found in the second hypervariable region of the first (outermost) domain.
(9) Through such routes, material of texture and density similar to that of the outermost cell wall layer appears to be deposited extracellularly.
(10) The polygonal cells in the outermost layer of the epidermis, though rich in phospholipid contain small amounts of cholesterol and its esters.
(11) As development progresses, immunofluorescence also appears, first, in the outermost zone of the retina and then in the plexiform layers.
(12) Therefore, neurons in the outermost layers of reaggregates, mostly consisting of amacrine cells, were studied with cell-attached recording.
(13) It is concluded that the 193 nm photons have such a shallow penetration depth, being limited to the outermost epithelial cells, that classical photokeratitis occurs from the fluorescence emitted at the corneal epithelial absorption site.
(14) Cellular actin was concentrated in the outermost thin cytoplasmic layer and in microvilli.
(15) The innermost ciliar of this zone were shorter than the outermost.
(16) Collecting ducts in the outermost portion of the inner stripe of the outer medulla and cells of the juxtaglomerular apparatus also expressed A1 adenosine receptor mRNA.
(17) Mineral and fluoride concentration changes in the outermost layers of bovine enamel (depth less than 1 micron) were measured after demineralization in unbuffered hydroxyethylcellulose gels of pH = 5.4 with an intrinsic fluoride concentration of about 0.02 ppm.
(18) Three distinct spore coats were detected, the outermost of which was composed of seven layers.
(19) In unaffected intima and in fatty streaks, the cells with lipid inclusions were found predominantly in the outermost intimal layer including the connective tissue and in part of the median hyperplastic layer.
(20) The outermost cuticulin layer of the cuticle in instars II-VI is elevated to form a dense mat of epicuticular hairs.
Utmost
Definition:
(a.) Situated at the farthest point or extremity; farthest out; most distant; extreme; as, the utmost limits of the land; the utmost extent of human knowledge.
(a.) Being in the greatest or highest degree, quantity, number, or the like; greatest; as, the utmost assiduity; the utmost harmony; the utmost misery or happiness.
(n.) The most that can be; the farthest limit; the greatest power, degree, or effort; as, he has done his utmost; try your utmost.
Example Sentences:
(1) Differentiation between these two types of lesions is of utmost importance since the surgical approach will be different.
(2) In order to achieve guineaworm eradication in 1990s, the Guineaworm Eradication Programme (GWEP) should operate with utmost efficiency; and needs to be concurrently evaluated for timely corrective measures.
(3) The pH of the extraction buffer was of the utmost importance, since it was demonstrated that a pH greater than 5 would give rise to false signals.
(4) Whereas live Toxoplasma "vaccines" may be effective in sheep and goats, the eventual preparation of a killed vaccine capable of inducing long-term protection is of the utmost importance.
(5) Despite advantages and technological advances in the techniques of dental casts and ceramics attachment to metal, plastic materials for crown and bridge facetting are still of utmost importance for prosthetic procedures.
(6) * * * Stalker, meanwhile, having made his decision, pursued Tape 042 with the utmost vigour.
(7) Early recognition of the major peroxisomal disorders in which functional peroxisomes are virtually absent, leading to a generalised impairment of peroxisomal functions, is of utmost importance, as this will enable the prenatal diagnosis of these severe diseases in future pregnancies.
(8) It is incumbent on the US, Britain and France to do their utmost to help the country win the peace.
(9) We conclude that the stimulation of Pk-C is of utmost importance for OL regeneration.
(10) However, it is of utmost importance that the institutes in "Eastern Europe" establish these standards as soon as possible in order to be competitive and to be able to join research-projects with "Western" universities - a necessary source of income.
(11) A consultant knowledgeable in the problems of the spinal cord injured can be of utmost benefit especially in the labor and delivery process.
(12) Intubation, artificial ventilation, fluid administration (electrolyte-solution) are of utmost importance for their survival and to reduce the frequency of major complications.
(13) As such, we treat any such allegations with the utmost seriousness and we will be contacting Jess to offer to discuss her concerns in full.” Sutton, in his own statement, said: “I wholeheartedly deny that I said or did anything other than act with complete professionalism in my dealings with Jess.
(14) Incidence of renal hydatid cyst is rare and its diagnosis should be made with the utmost care and after subjecting the patient to intensive investigations to exclude other pathologies.
(15) Both numbering systems initiate at the utmost 5' terminus of mRNA synthesis; this 5' initiator nucleotide is assigned 1.
(16) He fulfilled a difficult role in a progressive and compassionate way … he has done his utmost to transform the CPS's record on rape and domestic violence, delivering improved conviction rates for both.
(17) This is of the utmost importance, both epidemiologically and from the individual patient's point of view, and is a prerequisite in preventing the spread of HIV infection.
(18) This may be partly due to excessive patient fear according to the general belief that the heart is the utmost important part of life.
(19) Vaginal scanning of the ovaries and the uterus is a diagnostic and monitoring tool of utmost importance in assisted conception.
(20) In severe cases where hemorrhages play so large a role, albeit infrequently, the specific action of iron in interference with coagulation mechanisms is of the utmost importance.