(v. t.) To grow out of or away from; to grow too large, or too aged, for; as, to outgrow clothing; to outgrow usefulness; to outgrow an infirmity.
Example Sentences:
(1) Further management of the congenital cases was based on the experience that children outgrow this disorder; periodic dilatation may augment the natural process.
(2) Our findings lead us to support a conservative attitude regarding surgery, at least if only mild symptoms are present, If the patients can be satisfactorily treated medically, they seem to outgrow their symptoms in early childhood.
(3) Vegetative cells outgrowing from glycerol-induced myxospores were regularly pleomorphic, a condition that persisted through the first cell division.
(4) Small tumor fragments were transferred into culture flasks and cultured until a confluent monolayer was formed by the outgrowing cells.
(5) Chinese hamster V79 multicell spheroids growing in tissue culture exhibit many of the same properties as solid tumors outgrowing their blood supply, including the spontaneous development of both noncycling and hypoxic cell populations expected to be resistant to many chemotherapeutic agents.
(6) In the long-term experiments, with the lower TNF doses, in situ evidence of regrowth was observed (outgrowing zones in the nodules) on about the 40th day of treatment, and nodule recovery was confirmed by the resumption of DNA synthesis measured on the 50th day of treatment.
(7) Whereas the intramembranous particle number in glial pseudopodia is only slightly lower than in their perikaryal plasmalemma, the number of particles in outgrowing axons increases about eightfold from the periphery towards the perikaryon.
(8) The sequence encoding the most efficient trans-activation-responsive region did not outgrow others.
(9) More efficient glucose uptake enabled a mutant to outgrow its parent and caused a decrease in the steady-state glucose concentration in the chemostat.
(10) The outgrowing serotonergic fibers from the mesencephalic raphe graft showed a hyperinnervation pattern in the cerebellar cortex adjacent to the graft.
(11) Parents were the first to suspect the hearing loss in 48 cases but more often than not were told that the child would outgrow it or was too young to test.
(12) These findings suggest that the plasmalemma of the outgrowing nerve, and especially of the growth cone, is immature and that maturation is accompanied by the insertion of intramembranous particles.
(13) 146:430-432, 1981) we isolated three genes involved in Bacillus subtilis spore outgrowth by screening the library by hybridization with labeled RNA from outgrowing spores in the presence of an excess of unlabeled vegetative RNA.
(14) Spores of the mutant synthesized no DNA when germinated at high temperature, although an outgrowing cell appeared.
(15) Only the inner surface of the vitelline membrane has this growth-promoting potential, which markedly and progressively declines during incubation in ovo because of systemic factors rather than because of a direct influence by the outgrowing yolk sac-serosal membrane.
(16) Fluorescence immunohistochemistry revealed the presence of the integrin beta 1-chain on the outgrowing neurites.
(17) Major contributors to the outgrowing axon's environment are the lumbosacral (LS) somites which give rise to limb muscle cells and the LS somatopleural mesoderm which gives rise to limb connective tissues.
(18) Most children do outgrow their respiratory symptoms but not the susceptibility of their airways to allergens.
(19) In the presence of inhibitors affecting membrane potential, vegetative cells were as sensitive to chloroquine as outgrowing spores.
(20) These results indicate that serotonergic and dopaminergic neurons located within the mesencephalic raphe graft clearly differed from each other in their ability to extend their processes into the host cerebellum, which provides further evidence for the existence of specific interactions between outgrowing serotonergic fibers and their terminal fields (targets).
Outgrowth
Definition:
(n.) That which grows out of, or proceeds from, anything; an excrescence; an offshoot; hence, a result or consequence.
Example Sentences:
(1) Dibutyryl cyclic AMP (dbcAMP) treatment of Neuro 2A neuroblastoma cells induces cell differentiation and neurite outgrowth.
(2) Histochemical and immunocytochemical staining of the outgrowths with reagents that depict epithelial, myoepithelial, and lactating alveolar cells (peanut lectin alone, monoclonal and polyclonal antibodies to rat caseins) indicate similar cell compositions and arrangements for all outgrowths irrespective of their source; these are also similar to the mammary glands of the perphenazine-stimulated or lactating hosts.
(3) This study demonstrates that a second classical neurotransmitter, dopamine, can act to suppress regenerative neurite outgrowth.
(4) Salt concentrations slightly lower than those providing inhibition tended to extend spore outgrowth time at low temperatures.
(5) Urban ambulance systems emerged in the second half of the 19th century as an outgrowth of military experiences in both Europe and America.
(6) Adhesion to a substrate results in outgrowth of the cells and monolayer formation, even when extensive cell damage had occurred.
(7) These results suggest that purified laminin can facilitate and guide process outgrowth of 5-HT, DA and NE neurons during early developmental stage, but does not induce sprouting on these same fiber types in the adult brain.
(8) These data suggest that the induction of tau and MAP1 in response to NGF promotes microtubule assembly and that these factors are therefore key regulators of neurite outgrowth.
(9) However, whereas a critical value of N-CAM expression is required for increased neurite outgrowth, with small increases above this value having substantial effects, N-cadherin promotes neurite outgrowth in a highly linear manner.
(10) Outgrowth of neurites from neuronal cells was promoted by precoating the metal surface with either laminin or neurite promotion factor.
(11) Previous work from our laboratory had shown that goldfish retinal fragments explanted onto a polylysine substratum 1 to 2 weeks following optic nerve crush exhibit a striking clockwise pattern of neuritic outgrowth.
(12) The 33 kDa C-terminal cell and heparin-binding fragment of FN, in particular, is a strong promoter of CNS neurite outgrowth.
(13) Spontaneous outgrowth of immortalized Epstein-Barr virus (EBV) infected B-cell clones will occur from cultures of peripheral blood mononuclear cells (PBMNCs) of some persons with a history of EBV infection.
(14) The time of axonal outgrowth and the location of the cells in the developing embryo were determined by filling RS neurons retrogradely with horseradish peroxidase from their growing axons over a series of developmental stages.
(15) We have, therefore, developed a tool that allows us to measure microtubule polymerization equilibria out the neurites of cells in culture, which will allow us to test hypotheses that factors which affect neurite outgrowth do so by means of effects on microtubule polymerization equilibria.
(16) Molecular characterization of such genes could lead to the identification of molecules critical in axonal outgrowth and guidance in higher organisms.
(17) Recombinant F-spondin promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro.
(18) Synchrony was documented by nuclear staining and fluorescence microscopy, and by determining the variation of the buoyant density of the cells during outgrowth.
(19) Extraction of the recombinant proteins from inclusion bodies by guanidinium chloride, followed by two column chromatography steps, produced high yields of pure CNTF that supported survival and neurite outgrowth from embryonic chick ciliary neurons in culture.
(20) Reducing the inoculum to 10(4) delayed but did not prevent spore outgrowth and toxin release at pH levels below 4.6.