(1) While estradiol levels were equivalent in these two groups, the rise in LH after ovariectomy was prevented by the immediate administration in the pseudo-intact rats, while the augmented plasma LH levels present three weeks following ovariectomy were only reduced by 50% as a result of delayed estradiol treatment.
(2) Decreased levels of receptors for estradiol-17beta, progesterone, and prolactin were found in the tumors remaining after ovariectomy while treatment with the dose (24 mug) of RU 16117, efficient to inhibit tumor growth, has a similar inhibitory effect on the levels of estradiol-17beta and prolactin receptors.
(3) Neonatal ovariectomy raised 3H-estradiol concentrations in all tissues, except hippocampus and anterior pituitary, suggesting an increase in nonspecifically bound hormone.
(4) The osteopenic effects of prednisolone and ovariectomy were additive and independent.
(5) Estrous cycles were not disrupted by removal of the autogenous ovaries 8 wk after the grafting, indicating that grafted ovaries began functioning before or within days after ovariectomy.
(6) Both experiments were conducted using an animal model in which pulsatile secretion of gonadotropin-releasing hormone (GnRH) and endogenous secretion of ovarian steroids were eliminated by ovariectomy during seasonal anestrus and treatment with Silastic implants which maintained a luteal-phase level of serum progesterone.
(7) While the production of material rich in cysteine increases after ovariectomy (Dürnberger et al., 1978), the fine structure of the cells is essentially unchanged.
(8) In submandibular glands, 1 to 4 weeks after ovariectomy, no changes were observed in percentages of the acinar, intercalated duct, and granular convoluted tubular areas occupying photomicrographs.
(9) The results demonstrated that both oestradiol and tamoxifen induced a temporary growth delay, whereas ovariectomy of the host had no effect on the growth of the tumour.
(10) A similar effect was detected in them after combined adrenal- and ovariectomy.
(11) After ovariectomy, LH-beta mRNA levels increased 2- to 2.5-fold, while alpha mRNA levels increased 2.5-fold 6 and 10 days after ovariectomy.
(12) Within 6 h of ovariectomy in adult rats with 4-day estrous cycles, plasma FSH titers were significantly elevated above those of sham-operated controls at all stages of the estrous cycle, whereas plasma LH concentrations were raised by ovariectomy only during diestrus day 2, proestrus or estrus.
(13) Following unilateral ovariectomy in the rat, the remaining ovary undergoes rapid compensatory changes including an increase in the number of antral follicles (follicular activation) and an increase in ovarian weight (compensatory ovarian hypertrophy).
(14) However, ovariectomy induces female beta-cell degeneration similar to that in the males.
(15) Morphological alterations in the shape of germinal centres was noted after ovariectomy in adult and immature mice.
(16) In spite of the weak feedback response of the neonatal rats to ovariectomy, diethylstilbestrol suppressed the basal pituitary gonadotropin concentrations and the specific LH and FSH beta-chain mRNAs (p < 0.01-0.05).
(17) In uterus, ER mRNA increased 3- to 6-fold after ovariectomy, and returned to intact levels within 24 h of E2 replacement.
(18) Ovariectomy, on the other hand, depressed, whereas chronic administration of estradiol 17-beta enhanced the pressor response to the thromboxane mimic, but had no effect on the response to angiotensin II.
(19) A total of 35 menstruating women undergoing ovariectomy were randomly divided into five groups of 7 patients each, receiving a 4-week treatment with oral clonidine, lisuride and sodium valproate, transdermal 17 beta-estradiol, or placebo.
(20) Thyroidectomy did not alter the concentration of serum IR-GnRH and IR-TRH in Ovx rats on days 70 and 90 post-ovariectomy.
Ovariotomy
Definition:
(n.) The operation of removing one or both of the ovaries; oophorectomy.
Example Sentences:
(1) In each group 16 females had ovariotomies on dioestrus II between 16 and 17 hours.
(2) A significant decrease in early receptivity was noted following bilateral ovariotomy on dioestrus II from 4 to 5 pm.
(3) Conservative treatment is only permissible if one is absolutely sure that the contro-lateral ovary is normal, and if there is the slightest doubt ovariotomy should be carried out to perform a biopsy.